Review: could Enbrel cause Stevens-johnson Syndrome?


Summary

Stevens-johnson syndrome is found among people who take Enbrel, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Methotrexate, and have Rheumatoid arthritis . We study 257,190 people who have side effects while taking Enbrel from FDA and social media. Among them, 163 have Stevens-johnson syndrome. Find out below who they are, when they have Stevens-johnson syndrome and more.

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Enbrel

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. (latest outcomes from Enbrel 245,876 users)

Stevens-johnson Syndrome

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe) has been reported by people with breathing difficulty, hypotension, pleural effusion, respiratory distress, staphylococcal infection (latest reports from 29,579 Stevens-johnson syndrome patients).

On Aug, 22, 2016

257,190 people reported to have side effects when taking Enbrel.
Among them, 163 people (0.06%) have Stevens-johnson Syndrome


Number of reports submitted per year:

Could Enbrel cause Stevens-johnson syndrome?

Time on Enbrel when people have Stevens-johnson Syndrome *:

  • < 1 month: 32.94 %
  • 1 - 6 months: 37.65 %
  • 6 - 12 months: 2.35 %
  • 1 - 2 years: 10.59 %
  • 2 - 5 years: 11.76 %
  • 5 - 10 years: 2.35 %
  • 10+ years: 2.35 %

Gender of people who have Stevens-johnson Syndrome when taking Enbrel *:

  • female: 70.55 %
  • male: 29.45 %

Age of people who have Stevens-johnson Syndrome when taking Enbrel *:

  • 0-1: 0.0 %
  • 2-9: 0.98 %
  • 10-19: 10.78 %
  • 20-29: 5.88 %
  • 30-39: 15.69 %
  • 40-49: 10.78 %
  • 50-59: 19.61 %
  • 60+: 36.27 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (86 people)
  • Psoriasis (15 people)
  • Psoriatic Arthropathy (13 people)
  • Osteoporosis (10 people)
  • Still's Disease Adult Onset (8 people)

Top co-used drugs for these people *:

  • Methotrexate (39 people)
  • Prednisolone (23 people)
  • Isoniazid (22 people)
  • Folic Acid (16 people)
  • Prednisone (13 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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