Enbrel and Stevens-johnson syndrome - from FDA reports


Summary

Stevens-johnson syndrome is found among people who take Enbrel, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Methotrexate, and have Rheumatoid arthritis . We study 375,857 people who have side effects while taking Enbrel from FDA. Among them, 191 have Stevens-johnson syndrome. Find out below who they are, when they have Stevens-johnson syndrome and more.

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Enbrel

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. (latest outcomes from Enbrel 377,262 users)

Stevens-johnson Syndrome

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe) has been reported by people with high blood pressure, convulsion, epilepsy, bipolar disorder, fever (latest reports from 34,801 Stevens-johnson syndrome patients).

On Jan, 23, 2017

375,857 people reported to have side effects when taking Enbrel.
Among them, 191 people (0.05%) have Stevens-johnson Syndrome


Number of reports submitted per year:

Could Enbrel cause Stevens-johnson syndrome?

Time on Enbrel when people have Stevens-johnson Syndrome *:

  • < 1 month: 31.25 %
  • 1 - 6 months: 37.5 %
  • 6 - 12 months: 2.08 %
  • 1 - 2 years: 9.38 %
  • 2 - 5 years: 10.42 %
  • 5 - 10 years: 5.21 %
  • 10+ years: 4.17 %

Gender of people who have Stevens-johnson Syndrome when taking Enbrel *:

  • female: 69.94 %
  • male: 30.06 %

Age of people who have Stevens-johnson Syndrome when taking Enbrel *:

  • 0-1: 0.0 %
  • 2-9: 0.78 %
  • 10-19: 10.94 %
  • 20-29: 5.47 %
  • 30-39: 13.28 %
  • 40-49: 11.72 %
  • 50-59: 20.31 %
  • 60+: 37.5 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (99 people, 51.83%)
  • Psoriasis (19 people, 9.95%)
  • Psoriatic Arthropathy (16 people, 8.38%)
  • Osteoporosis (10 people, 5.24%)
  • Ankylosing Spondylitis (10 people, 5.24%)

Top co-used drugs for these people *:

  • Methotrexate (44 people, 23.04%)
  • Prednisolone (23 people, 12.04%)
  • Isoniazid (22 people, 11.52%)
  • Folic Acid (16 people, 8.38%)
  • Prednisone (13 people, 6.81%)

Top other side effects for these people *:

  • Rashes (27 people, 14.14%)
  • Psoriasis (13 people, 6.81%)
  • Drug Eruption (12 people, 6.28%)
  • Rheumatoid Arthritis (11 people, 5.76%)
  • Fever (11 people, 5.76%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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