Review: could Enbrel cause Stevens-johnson syndrome (Erythema multiforme)?
Summary: Stevens-johnson syndrome is found among people who take Enbrel, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Methotrexate, and have Rheumatoid arthritis.
We study 174,980 people who have side effects while taking Enbrel from FDA and social media. Among them, 142 have Stevens-johnson syndrome. Find out below who they are, when they have Stevens-johnson syndrome and more.
You are not alone: join a mobile support group for people who take Enbrel and have Stevens-johnson syndrome >>>
Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. (latest outcomes from 175,543 Enbrel users)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe) has been reported by people with convulsion, high blood pressure, epilepsy, ill-defined disorder, bipolar disorder. (latest reports from 27,933 Stevens-johnson syndrome patients)
On Mar, 1, 2015: 174,980 people reported to have side effects when taking Enbrel. Among them, 142 people (0.08%) have Stevens-johnson Syndrome.
Time on Enbrel when people have Stevens-johnson syndrome * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Stevens-johnson syndrome||41.12%||32.71%||1.87%||7.48%||14.02%||0.93%||1.87% |
Gender of people who have Stevens-johnson syndrome when taking Enbrel * :
|Stevens-johnson syndrome||74.84%||25.16% |
Age of people who have Stevens-johnson syndrome when taking Enbrel * :
|Stevens-johnson syndrome||0.00%||0.00%||14.02%||8.41%||10.28%||14.02%||24.30%||28.97% |
Severity of Stevens-johnson syndrome when taking Enbrel ** :
How people recovered from Stevens-johnson syndrome ** :
Top conditions involved for these people * :
- Rheumatoid arthritis (77 people, 54.23%)
- Still's disease adult onset (18 people, 12.68%)
- Psoriatic arthropathy (16 people, 11.27%)
- Arthritis (14 people, 9.86%)
- Psoriasis (13 people, 9.15%)
Top co-used drugs for these people * :
- Methotrexate (49 people, 34.51%)
- Prednisolone (31 people, 21.83%)
- Isoniazid (27 people, 19.01%)
- Folic acid (20 people, 14.08%)
- Sol-melcort (18 people, 12.68%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Do you have Stevens-johnson Syndrome while taking Enbrel?
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- support group for people who take Enbrel and have Stevens-johnson Syndrome
- support group for people who take Enbrel
- support group for people who have Stevens-johnson Syndrome
Drugs in real world that are associated with:
Could your condition cause:
Can you answer these questions (Ask a question):
- Anyone experence colon cancer on enbrel?
I used Enbrel for about 9 years and developed colon cancer. There is no family history and the particular DNA of the cancer was highly unusual for colon cancer. Has anyone else experienced colon cancer after long term Enbrel use?
- Electrolyte imbalance due to diarrhea caused by enbrel
Electrolyte loss caused by the diarrhea side effect treatment or resolving this problem
- Can i connect by email with other patients that have hypoglycemia and stevens-johnson syndrome? (1 answer)
I have had hypoglycemia since childhood, and I have managed it easily until just this weekend. I got S-J two years ago from Bactrim. As I have healed from S-J very slowly and painfully, I was exercising hard, and working hard and slipped a little on not eating enough protein. I started dropping into sugar blackouts and it scared the crap out of me! Still working at being able to eat enough to straighten out low sugar levels. Any suggestions helpful, Thanks, Leann
- Is there a heath warning with a person taking enbrel being around a person with histoplasmosis?
The person taking enbrel is there a risk facator being around a person with histoplasmosis?
- Do i need to temporarily stop taking my enbrel and methotrexate (that i take every week) while i am on azithromycin for severe cold symptoms? (1 answer)
i have RA and take Enbrel and methotrexate every week. i am currently taking azithromycin, tussicaps and dexamethasone to treat a severe cold, cough, sore throat, etc. My question is should i stop taking the ra meds until my antibiotics and steroids are done? Or should i just continue as normal, don't want to get sicker than i already am!!!! thanks
More questions for: Enbrel, Stevens-johnson syndrome
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- Etanercept and irritability
I have been on Etanercept for 8 years for Psoriasis. Previous to this I was on
Methotrexate, Cyclosporine, Retinodes and ACTH injections.Since being on 25mg twice a week I have been 98% clear.The only side effect to date is "Irritability" which lasts about 24hrs.
This Drug has been my saving grace.
- Humira: my experience
I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.
I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(
I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.
I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.
My MD is going to get me onto another injectable that I take monthly. I forget its name.
- Vasculitis from enbrel
I have deep scars on my legs from vasculitis. This was caused by Enbrel. Initially no one would connect the two: per my rheumatologist 'no one has ever reported vasculitis as a side effect of enbrel.' (2003)
I had to suspend the enbrel for 8 weeks in preparation for complex abdominal surgery. The vasculitis started to heal. Several weeks after the surgery I resumed enbrel and the vasculitis returned by the second or third enbrel shot. The Dr was reluctantly willing to concede that 'it may have been the enbrel.'
The vasculitis was horrific. I've never felt so much pain, pain that wasn't abated in the least by pain medicine. My dermatologist describe it as being equivalent to a third degree burn: the skin dies, nerves start to regenerate but aren't protected by the dermis.
The scars look like I had flesh torn from my legs that didn't quite 'fill in.'
Rheumatologists are too pushy about these biological medicines. They brush past even the most serious side effects. Anything for mobility... I'd prefer not to skip to dialysis sessions or treatment for other organ failure!
More reviews for: Enbrel, Stevens-johnson syndrome
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