Review: could Estradiol cause Skin Lesion?


Skin lesion is found among people who take Estradiol, especially for people who are female, 50-59 old , have been taking the drug for 5 - 10 years, also take medication Humira, and have Hormone replacement therapy . We study 5,938 people who have side effects while taking Estradiol from FDA and social media. Among them, 172 have Skin lesion. Find out below who they are, when they have Skin lesion and more.

You are not alone

Join a support group for people who take Estradiol and have Skin lesion >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Estradiol has active ingredients of estradiol. It is often used in hormone replacement therapy. (latest outcomes from Estradiol 6,585 users)

Skin Lesion

Skin lesion has been reported by people with breathing difficulty, erythema multiforme, thrombocytopenia, itching, diarrhea (latest reports from 186,667 Skin lesion patients).

On Aug, 28, 2016

5,938 people reported to have side effects when taking Estradiol.
Among them, 172 people (2.9%) have Skin Lesion

Number of reports submitted per year:

Could Estradiol cause Skin lesion?

Time on Estradiol when people have Skin Lesion *:

  • < 1 month: 13.33 %
  • 1 - 6 months: 26.67 %
  • 6 - 12 months: 6.67 %
  • 1 - 2 years: 6.67 %
  • 2 - 5 years: 6.67 %
  • 5 - 10 years: 26.67 %
  • 10+ years: 13.33 %

Gender of people who have Skin Lesion when taking Estradiol *:

  • female: 97.08 %
  • male: 2.92 %

Age of people who have Skin Lesion when taking Estradiol *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.81 %
  • 30-39: 5.65 %
  • 40-49: 17.74 %
  • 50-59: 46.77 %
  • 60+: 29.03 %

Severity if Skin Lesion when taking Estradiol **:

  • least: 0.0 %
  • moderate: 77.78 %
  • severe: 11.11 %
  • most severe: 11.11 %

How people recovered from Skin Lesion **:

  • while on drug: 0.0 %
  • after off the drug: 11.11 %
  • not yet: 88.89 %

Top conditions involved for these people *:

  • Hormone Replacement Therapy (31 people)
  • Rheumatoid Arthritis (30 people)
  • Pain (16 people)
  • Depression (16 people)
  • Hypertension (13 people)

Top co-used drugs for these people *:

  • Humira (30 people)
  • Folic Acid (21 people)
  • Prednisone (18 people)
  • Aspirin (17 people)
  • Synthroid (16 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Skin lesion when taking Estradiol?

Browse all side effects of Estradiol

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Skin lesion

Skin lesion

Could your condition cause Skin lesion

Skin lesion

Can you answer these questions?

More questions for: Estradiol, Skin lesion

You may be interested in these reviews

More reviews for: Estradiol, Skin lesion

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.