Review: could Flexeril cause Aggression?


Aggression is found among people who take Flexeril, especially for people who are female, 40-49 old , have been taking the drug for 2 - 5 years, also take medication Chantix, and have Anxiety . We study 17,048 people who have side effects while taking Flexeril from FDA and social media. Among them, 122 have Aggression. Find out below who they are, when they have Aggression and more.

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Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 19,420 users)


Aggression has been reported by people with fever, agitation, weakness, drowsiness, fatigue (latest reports from 31,640 Aggression patients).

On Aug, 25, 2016

17,048 people reported to have side effects when taking Flexeril.
Among them, 122 people (0.72%) have Aggression

Number of reports submitted per year:

Could Flexeril cause Aggression?

Time on Flexeril when people have Aggression *:

  • < 1 month: 14.29 %
  • 1 - 6 months: 7.14 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 7.14 %
  • 2 - 5 years: 35.71 %
  • 5 - 10 years: 21.43 %
  • 10+ years: 14.29 %

Gender of people who have Aggression when taking Flexeril *:

  • female: 57.85 %
  • male: 42.15 %

Age of people who have Aggression when taking Flexeril *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.97 %
  • 20-29: 16.83 %
  • 30-39: 14.85 %
  • 40-49: 30.69 %
  • 50-59: 21.78 %
  • 60+: 12.87 %

Severity if Aggression when taking Flexeril **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 100 %
  • most severe: 0.0 %

Top conditions involved for these people *:

  • Anxiety (34 people)
  • Depression (33 people)
  • Smoking Cessation Therapy (29 people)
  • Pain (28 people)
  • Fibromyalgia (13 people)

Top co-used drugs for these people *:

  • Chantix (32 people)
  • Xanax (25 people)
  • Vicodin (25 people)
  • Paxil (22 people)
  • Ativan (21 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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