Flexeril and Dependence - from FDA reports


Dependence is found among people who take Flexeril, especially for people who are female, 40-49 old also take medication Xanax, and have Back pain. This review analyzes which people have Dependence with Flexeril. It is created by eHealthMe based on reports of 23,592 people who have side effects when taking Flexeril from FDA, and is updated regularly.

What to expect?

If you take Flexeril and have Dependence, find out what symptoms you could have in 1 year or longer.

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On May, 03, 2017

23,592 people reported to have side effects when taking Flexeril.
Among them, 47 people (0.2%) have Dependence

Number of reports submitted per year:

Could Flexeril cause Dependence?

Gender of people who have Dependence when taking Flexeril *:

  • female: 85.11 %
  • male: 14.89 %

Age of people who have Dependence when taking Flexeril *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 25.0 %
  • 30-39: 25.0 %
  • 40-49: 37.5 %
  • 50-59: 12.5 %
  • 60+: 0.0 %

Top conditions involved for these people *:

  • Back Pain (17 people, 36.17%)
  • Stress And Anxiety (13 people, 27.66%)
  • Pain (11 people, 23.40%)
  • Migraine (9 people, 19.15%)
  • Restless Leg Syndrome (8 people, 17.02%)

Top co-used drugs for these people *:

  • Xanax (21 people, 44.68%)
  • Lortab (20 people, 42.55%)
  • Stadol (18 people, 38.30%)
  • Valium (16 people, 34.04%)
  • Ambien (16 people, 34.04%)

Top other side effects for these people *:

  • Stress And Anxiety (25 people, 53.19%)
  • Depression (25 people, 53.19%)
  • Drug Withdrawal Syndrome (19 people, 40.43%)
  • Agitation (12 people, 25.53%)
  • Mood Swings (11 people, 23.40%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Dependence when taking Flexeril?


Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 26,564 users)


Dependence has been reported by people with migraine, quit smoking, depression, pain, stress and anxiety (latest reports from 5,497 Dependence patients).

Browse all side effects of Flexeril

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Drugs that are associated with Dependence


Could your condition cause Dependence


Related studies

What would happen?

Forecast new side effects and undetected conditions when you take Flexeril and have Dependence.

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