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Review: could Flexeril cause Restless legs syndrome (Restless leg syndrome)?





Summary: Restless legs syndrome is found among people who take Flexeril, especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years, also take medication Neurontin, and have Pain.

We study 14,466 people who have side effects while taking Flexeril from FDA and social media. Among them, 101 have Restless legs syndrome. Find out below who they are, when they have Restless legs syndrome and more.

You are not alone: join a mobile support group for people who take Flexeril and have Restless legs syndrome >>>

Flexeril

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 16,445 users)

Restless legs syndrome

Restless Legs Syndrome (a powerful urge to move your legs) has been reported by people with restless leg syndrome, osteoporosis, depression, high blood pressure, pain.(latest reports from Restless Legs Syndrome 16,008 patients)

On Dec, 14, 2014: 14,466 people reported to have side effects when taking Flexeril. Among them, 101 people (0.70%) have Restless Legs Syndrome.

Trend of Restless legs syndrome in Flexeril reports

Time on Flexeril when people have Restless legs syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Restless legs syndrome14.29%14.29%0.00%42.86%14.29%14.29%0.00%

Gender of people who have Restless legs syndrome when taking Flexeril * :

FemaleMale
Restless legs syndrome89.22%10.78%

Age of people who have Restless legs syndrome when taking Flexeril * :

0-12-910-1920-2930-3940-4950-5960+
Restless legs syndrome0.00%0.00%0.00%3.37%3.37%13.48%46.07%33.71%

Severity of Restless legs syndrome when taking Flexeril ** :

leastmoderateseveremost severe
Restless legs syndrome14.29%57.14%28.57%0.00%

How people recovered from Restless legs syndrome ** :

while on the drugafter off the drugnot yet
Restless legs syndrome0.00%33.33%66.67%

Top conditions involved for these people * :

  1. Pain (37 people, 36.63%)
  2. Muscle spasms (32 people, 31.68%)
  3. Restless legs syndrome (24 people, 23.76%)
  4. Depression (24 people, 23.76%)
  5. Upper respiratory tract infection (20 people, 19.80%)

Top co-used drugs for these people * :

  1. Neurontin (44 people, 43.56%)
  2. Prilosec (32 people, 31.68%)
  3. Ativan (31 people, 30.69%)
  4. Coumadin (28 people, 27.72%)
  5. Celebrex (27 people, 26.73%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Restless Legs Syndrome while taking Flexeril?

You are not alone! Join a mobile support group:
- support group for people who take Flexeril and have Restless Legs Syndrome
- support group for people who take Flexeril
- support group for people who have Restless Legs Syndrome

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  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    (Asked by a 34 year old woman who has Muscle Tightness, Muscle Contractions Involuntary, Ptsd, Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension, Anxiety Disorder, Depression, Bulimia, Exhaustion, Fatigue, Lethargy, Tiredness, Weariness, ADHD, and takes Nuvigil, Prozac, Flexeril, Topamax, Xanax, Adderall 30)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • What can i do to help my wife who is on ambien and sometimes has horrible restless leg syndrome?
    (Asked by a 25 year old woman who has ADD, Restless Leg Syndrome, Insomnia, and takes Adderall, Ambien)
    She will take her meds like a hour and a half before actually going to sleep. The Zambian that is and sometimes she has uncontrolled restless leg syndrome. She has to move them a certain way and everything. This last time it lasted a hour and a half. I was just wondering if there is anything I could do to belp.?
  • Why would i get copd since i never smoked?
    (Asked by a 62 year old woman who has Rheumatoid Arthritis, PBC, AIH, Asthma, and takes Vitamin D, Calcium Carbonate, Anturol, Morphine Sulfate, Levothyroxine Sodium, Pyridium, Cyclobenzaprine Hydrochloride, Azathioprine, Proair Hfa, Advair Diskus 250/50, Combivent)
    I have several autoimmune disorders, I was shocked to get the COPD diagnosis since I have never smoked but I had second hand smoke first 23 years of my life.
    My doctor said my Autoimmune Hepatitis and Primary Biliary Cholingitis set me up for COPD.
  • Has abilify affected your ability to make good decisions?
    (Asked by a 73 year old woman who has Tachycardia, Depression, Fibromyalgia, Anemia, Barrett's Esophagus, Temporal Arteritis, Restless Leg Syndrome, Disautonomia, Autoimmune Retinopathy, Polymyalgia Rheumatica, Myasthenia Gravis, Addison's Disease, and takes Abilify)
    My husband and I are 73. We had a paid off home and money in the bank until the past 3 years. We have made some terrible decisions and now we are practically penniless. We couldn't understand why we had made such bad decisions and let someone talk us into losing our money. We have also been on Abilify about the same amoount of time and I noticed that the commercials say a side affect can be lack of judgement or something to that effect. Has anyone else had this happen?
  • My sister has a past addiction to morphine. is solonpas addictive?
    (Asked by a 45 year old woman who has Depression, Restless Leg Syndrome, Arthritis In Lower Back, Mild Brain Damage From Suicide Attempt, PTSD)
    I take of my baby sister, because in 2010 she tried to take her life with drugs, alcohol and. Cocaine. She complains of pain in her lower back, due to an injury in 1998, which led to surgery, which led to her addictiction to Morphine. She was diagnosed with Arthritis in her back where she had surgery. She's not allowed anything stronger than an extra strength Tylenol, Alleve and Advil.

    My question would be "Is Solonpas comparable to the OTC pain meds and is it addictive?"

More questions for: Flexeril, Restless legs syndrome

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  • I wish i had never taken ambien
    (Posted by a 43 year old woman who has Fibromyalgia, and takes Savella, Lyrica, Synthroid, Effexor, Tramadol, Duragesic-50, Flexeril, Ambien)
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.
  • Pristiq, epilim, sifrol, immovane, valium, mobic
    (Posted by a 41 year old woman who has Congenital Scoliosis, Claustrophobia, Flashbacks And Nightmares, Anxiety Disorder, Restless Legs Syndrome, Depression, and takes Mobic, Pramipexole Dihydrochloride, Diazepam, Valproate Sodium, Pristiq )
    I started out with mild burnout depression in 2009 and was put on a low dose of Lexapro, which picked me up fantastically. I had been given low (2mg) Valium before for muscle relaxant purposes due to my scoliosis complications. Both these worked well. Then in 2010 I was drugged and raped and almost suffocated by my flatmate. I plummeted after 3 days of numb shock, into the deep dark abyss of major depression, and became fearful about everything. I couldn't enter a shop if there was a queue of men in there for example. Finding myself with complete lack of motivation, neglecting housework, making mistakes constantly at work, I returned to the doctor. He doubled my Lexapro dose. I went back as instructed and was not feeling any better and could not cope with how I felt, so he sent to a psychiatrist. The psychiatrist added Epilim ie pramipexole hyrochloride (low dose) for mood balance, upped the Valium ie daizepam, to 5mg, and prescribed Immovane for my insomnia and terrifying nightmares. Time went on, and I built a tolerance to Lexapro, so he put me on Pristique 200 and Epilim 200. Then I had to have both those doubled (400 each) and I take them twice a day. I have had NO negative side effects at all, and they work excellently for me. As for the restless legs syndrome, that was diagnosed before I was on these medications. The Sifrol had to be increased too as I was told it had to have time to gradually build up in my system. It makes a great difference to my quality of sleep and how my legs feel the next day.
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    (Posted by a 56 year old man who has Major Depressive Disorder, Restless Leg Syndrome, Lactose Intolerance)
    After taking my first dose of Clonazapam, it seemed my lactose intolerance flared up for 24 hours or more. Flatulence all through the period and watery stool in the morning. Does anyone else find their lactose intolerance triggered by the lactose in Clonazapam?
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    Ten years ago, I was not optimist about my future. Today, I am full of hope, wonder, energy, and excitement. I believe we have the ability to heal ourselves, but we must be diligent in our pursuit of knowledge, persistent and strong in our will to make lifestyle changes, and patient that results will come as long as we are doing all the right things. By the way, giving up foods I had eaten my entire life was not difficult at all once I did it long enough to realize the tremendous benefits of not eating them.
  • Savella & synthroid hell! (3 responses)
    (Posted by a 47 year old woman who has Hypermetanephrinemia, Insomnia, Palpitations, Hyperhidrosis, and takes Flexeril, Dilaudid, Morphine Sulfate, Fentanyl, Synthroid, Savella)
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