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Review: could Fluconazole cause Depression?

Summary: Depression could be caused by Fluconazole, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Zometa, and have Pain.

We study 19,804 people who have side effects while taking Fluconazole from FDA and social media. Among them, 497 have Depression. Find out below who they are, when they have Depression and more.

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Fluconazole

Fluconazole (latest outcomes from 20,430 users) has active ingredients of fluconazole. It is often used in vaginal yeast infection.

Depression

Depression (latest reports from 1,140,778 patients) has been reported by people with quit smoking, multiple sclerosis, pain, pain relief by acupuncture, acupuncture and pain.

On Apr, 13, 2014: 19,803 people reported to have side effects when taking Fluconazole. Among them, 497 people (2.51%) have Depression. They amount to 0.04% of all the 1,146,434 people who have Depression on eHealthMe.

Trend of Depression in Fluconazole reports

Time on Fluconazole when people have Depression * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Depression55.77%15.38%0.00%1.92%23.08%3.85%0.00%

Age of people who have Depression when taking Fluconazole * :

0-12-910-1920-2930-3940-4950-5960+
Depression0.00%2.11%4.22%9.37%11.71%20.84%22.01%29.74%

Severity of Depression when taking Fluconazole ** :

n/a

How people recovered from Depression ** :

n/a

Top conditions involved for these people * :

  1. Pain (65 people, 13.08%)
  2. Multiple myeloma (55 people, 11.07%)
  3. Depression (53 people, 10.66%)
  4. Metastases to bone (36 people, 7.24%)
  5. Anxiety (36 people, 7.24%)

Top co-used drugs for these people * :

  1. Zometa (152 people, 30.58%)
  2. Cephalexin (126 people, 25.35%)
  3. Dexamethasone (124 people, 24.95%)
  4. Prednisone (118 people, 23.74%)
  5. Ambien (114 people, 22.94%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Fluconazole, Depression

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On eHealthMe, Fluconazole (fluconazole) is often used for vaginal yeast infection. Find out below the conditions Fluconazole is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Fluconazole used for and how effective is it:

Other drugs that are used to treat the same conditions:

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Could your condition cause it?

Comments from related studies:

  • From this study (2 days ago):

  • I have so many problems and take so many medicines I am trying to find out what works what doesn't what interacts which drugs are necessary - 2 years ago had bilateral total knee replacement -- trying to quit smoking, did quit for about a year then started up part time

    Reply

  • From this study (5 days ago):

  • Recently Dxd w/ toxic multinodular goiter/hyperthyroidism. Fibromyalgia for 20+ years. Had to titrate off Savella 100 mg. BID due to hyperthyroidism. Now all above symptoms have worsened. Because thyroid blood work was in normal range ( although I had been on low iodine diet for 2 months, which should keep in normal range) endocrinologist said see me in six months! No instructions, no explanations. Can't find much about Plummer's online! Had bad reaction during uptake scan & ER said due to RAI. If levels had been high on blood work following scan results, Dr wanted to do RAI Ablation. I am a.) Afraid of worse reaction; b.) Ablation not working, having to be repeated; c.) Ultimately having to have thyroid removed surgically.
    I need to know my options! What should I be doing now? Anger and aggression, plus crying all the time are taking over my life. Savella was like a miracle drug for my fibromyalgia, but since it was an SNRI I am wondering how much of my problems is from stopping that. I did titrate off professionally, but had been on it over 3 years. Also wondering if it, hyperthyroidism or both are reason I am on four bp meds as cardiologist says heart is healthy. No history of stroke or seizures.
    Is there anyone out there who can give me direction? Every day is worse. Also having injections in c- spine to determine if neurological surgery w/ help w/ spinal cord compression. First was done Monday.
    Eyes also not focusing! Fibromyalgia or hyperthyroidism? Dr says I have 20/20 in each eye individually & field vision test okay. Still can't see TV or anything up close such as cosmetic needs for face! Nothing helps close vision. Glasses will help distance clear enough for now.

    Reply

  • From this study (5 days ago):

  • Sarcoidosis caused complete heart block. Pacemaker implanted in December 2009 but for the past two years I have had palpitations caused by around 3.7 million ectopic heartbeats per year.

    Sarcoidosis also in lungs and eyes. Extended use of Pred Forte caused development of cataracts, one of which has been removed and I am awaiting the second operation.

    Breathlessness is caused by lack of oxygen entering the bloodstream and my ongoing heart problems

    Rarely able to sleep properly due to pain, sleeping for about 20 minutes at a time when I become so exhausted that the pain can't keep me awake

    Muscle and joint pain have made me weak and clumsy.Pain is felt all over, from head to toes along with muscle cramps and intense burning sensation to skin on lower legs.

    ACE levels fluctuate but average 110 - 150.

    Blood pressure on average is 150 / 78 - no treatment given

    I also take Nefopam Hydrochloride (Acupan) for pain but this drug is not on the list.

    Immobility, fatigue and constant pain have left me very depressed ad harbouring thoughts of suicide. My 15 year old granddaughter has lived with me since the death of my daughter 11 years ago and it is my hope that I will live long enough to see her settled in college and independent after which the only thing I have to look forward to is to end my own suffering.

    Reply

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More questions for: Fluconazole, Depression

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More reviews for: Fluconazole, Depression

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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