Review: could Folic Acid cause Melasma?


Melasma is reported only by a few people who take Folic Acid. We study 104,382 people who have side effects while taking Folic acid from FDA and social media. Among them, 2 have Melasma. Find out below who they are, when they have Melasma and more.

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Folic Acid

Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. (latest outcomes from Folic acid 105,359 users)


Melasma (the mask of pregnancy when present in pregnant women) is a tan or dark skin discoloration) has been reported by people with birth control, heavy or prolong menstrual bleeding, depression, multiple sclerosis, hormone replacement therapy (latest reports from 577 Melasma patients).

On Oct, 23, 2016

104,382 people reported to have side effects when taking Folic Acid.
Among them, 2 people (0.0%) have Melasma

Number of reports submitted per year:

Could Folic acid cause Melasma?

Age of people who have Melasma when taking Folic Acid *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 50 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 50 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (1 person, 50.00%)
  • Migraine (1 person, 50.00%)
  • Hypersensitivity (1 person, 50.00%)

Top co-used drugs for these people *:

  • Methotrexate (2 people, 100.00%)
  • Multi-Vitamins (1 person, 50.00%)
  • Flonase (1 person, 50.00%)
  • Enbrel (1 person, 50.00%)
  • Alendronate Sodium (1 person, 50.00%)

Top other side effects for these people *:

  • Synovitis (1 person, 50.00%)
  • Injection Site Erythema (1 person, 50.00%)
  • Dental Caries (1 person, 50.00%)
  • Bone Marrow Oedema (1 person, 50.00%)
  • Arthroscopy (1 person, 50.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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