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Review: could Gabapentin cause Depression?





Summary: Depression is found among people who take Gabapentin, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months, also take medication Zometa, and have Pain.

We study 36,957 people who have side effects while taking Gabapentin from FDA and social media. Among them, 1,550 have Depression. Find out below who they are, when they have Depression and more.

You are not alone: join a mobile support group for people who take Gabapentin and have Depression >>>

Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. (latest outcomes from Gabapentin 39,518 users)

Depression

Depression has been reported by people with quit smoking, multiple sclerosis, pain, osteoporosis, acne.(latest reports from Depression 254,062 patients)

On Dec, 14, 2014: 36,957 people reported to have side effects when taking Gabapentin. Among them, 1,550 people (4.19%) have Depression.

Trend of Depression in Gabapentin reports

Time on Gabapentin when people have Depression * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Depression24.29%27.68%16.95%11.86%12.99%5.08%1.13%

Age of people who have Depression when taking Gabapentin * :

0-12-910-1920-2930-3940-4950-5960+
Depression0.00%0.07%0.44%3.03%11.61%24.11%33.21%27.51%

Severity of Depression when taking Gabapentin ** :

leastmoderateseveremost severe
Depression6.25%50.00%33.33%10.42%

How people recovered from Depression ** :

while on the drugafter off the drugnot yet
Depression3.57%35.71%60.71%

Top conditions involved for these people * :

  1. Pain (283 people, 18.26%)
  2. Depression (275 people, 17.74%)
  3. Anxiety (170 people, 10.97%)
  4. Hypertension (158 people, 10.19%)
  5. Multiple sclerosis (143 people, 9.23%)

Top co-used drugs for these people * :

  1. Zometa (293 people, 18.90%)
  2. Aspirin (280 people, 18.06%)
  3. Neurontin (244 people, 15.74%)
  4. Cymbalta (243 people, 15.68%)
  5. Aredia (209 people, 13.48%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Depression while taking Gabapentin?

You are not alone! Join a mobile support group:
- support group for people who take Gabapentin and have Depression
- support group for people who take Gabapentin
- support group for people who have Depression

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Drugs in real world that are associated with:

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Can you answer these questions (Ask a question):

  • Does anyone else have peripheral neuropathy? anyone have pn with lichen sclerosus? i have pain in hands, feet and face.
    Pain much worse at end of day and when I overdo. Sleep difficult - but essential! Feel so much better if I get 6+ hours. At the moment, very distressed by swollen lips (mostly inside mouth) and tissue surrounding eyes. I'm sure I have some arthritis in my fingers and toes. I also have had lichen sclerosus on my skin for nearly 20 years. Have had the PN for 15 years or so. I'm afraid that the medications can actually make the condition worse. If anyone has any suggestions, I'm all ears!
    Reply
  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
    Reply
  • Has anyone been helped by taking lexapro and wellbutrin?
    I am the mom of a 22 year old who is trying to get through college and can't seem to find the right meds for depression. She is taking Lexapro and I am wondering if adding Wellbutrin will help.
    Reply
  • Effect of zoloft and vitamin d on seborrheic keratoses
    Has anyone noted a change in their seborrheic keratoses after taking Zoloft?
    Any changes after taking Vitamin D either 5000 IU daily or 50000 IU weekly
    Reply
  • Can anyone comment on recurrent depressions in fall and spring
    for many years i suffer depression twice a year spring and fall
    Reply

More questions for: Gabapentin, Depression

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  • Cough and gabapentin
    Have chronic cough for 6 yr's at least.3 yr's ago it got bad enough to seek doc. Help. Took all the tests . Tried to tell me I had asthma,copd, ect. Put me on sprivia, symbicort, singular, helped a little for awhile. Long story short. Went to one doc. He asked me some questions about my cough. Figured out it usually started with a tickle on the left side of my throat. And he put me on gabapentin 300mg. 3 times Aday. Which is for nerve damage. It took about 7days to see some change. And about 35days To stop the chronic cough. I still cough once in awhile. But no chronic coughing. Now I am going to try and see if I can stop the other med,s one at a time and see what happens
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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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