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Review: could Gabapentin cause Depression?

We study 36,857 people who have side effects while taking Gabapentin from FDA and social media. Among them, 1,486 have Depression. Find out below who they are, when they have Depression and more.

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Gabapentin

Gabapentin (latest outcomes from 39,406 users) has active ingredients of gabapentin. It is often used in neuralgia.

Depression

Depression (latest reports from 1,148,155 patients) has been reported by people with quit smoking, multiple sclerosis, pain, osteoporosis, high blood pressure.

On Sep, 11, 2014: 36,857 people reported to have side effects when taking Gabapentin. Among them, 1,546 people (4.19%) have Depression.

Trend of Depression in Gabapentin reports

Time on Gabapentin when people have Depression * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Depression24.86%27.17%16.76%12.14%13.29%5.20%0.58%

Age of people who have Depression when taking Gabapentin * :

0-12-910-1920-2930-3940-4950-5960+
Depression0.00%0.07%0.45%3.04%11.65%24.11%33.23%27.45%

Severity of Depression when taking Gabapentin ** :

leastmoderateseveremost severe
Depression4.55%50.00%34.09%11.36%

How people recovered from Depression ** :

while on the drugafter off the drugnot yet
Depression4.17%37.50%58.33%

Top conditions involved for these people * :

  1. Pain (282 people, 18.24%)
  2. Depression (272 people, 17.59%)
  3. Anxiety (169 people, 10.93%)
  4. Hypertension (158 people, 10.22%)
  5. Multiple sclerosis (143 people, 9.25%)

Top co-used drugs for these people * :

  1. Zometa (293 people, 18.95%)
  2. Aspirin (280 people, 18.11%)
  3. Neurontin (244 people, 15.78%)
  4. Cymbalta (243 people, 15.72%)
  5. Aredia (209 people, 13.52%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Depression while taking Gabapentin?

Get connected! Join a mobile support group:
- group for people who take Gabapentin and have Depression
- group for people who take Gabapentin
- group for people who have Depression

Comments from related studies:

  • From this study (1 month ago):

  • My most severe symptoms would be the shortness of breath, muscle weakness and this chronic pain under my left rib that goes around to my back and up to my shoulder blade. Occasionally that pain will go to my left chest, clavicle and jaw. But all of my pain is on the left side. I have degenerative disc disease and spinal stenosis too. Chronic headaches are dizziness are awful and debilitating.

    Reply

  • From this study (2 months ago):

  • Was prescribed gabapentin 7 yr ago for left fibula fracture and foot dislocation. Severe foot nerve pain.both ankles have been swelling for years.was told by Dr's it was chronic edema from injury. But never explained why in both ankles? ? In last month my feet and calves have became severely red like red Sox . itching burning pain different from nerve damage.now pain up in calves.and in behind legs. Symptoms are identical to stevens johnson syndrome I'm seeing from research. My PCP didn't know what it is and wanted a mri.im scared and worried. I am going to get of gabapentin ASAP .need my Dr to find alternative medicine and ween off . hoping that it's curable or will go away.

    Reply

  • From this study (3 months ago):

  • Increased dreaming and sleepwalking on neurontin. Found it affects me like clockwork. I must take it by 7pm in order to get up by 6am; otherwise I'm too woozy to drive even by 8am. Trying to make sure I took it early enough, I've taken at 6pm, but I wake up at 5am (I'm not a morning person!) like a like went off in my head! The swelling in my ankles is common with amlodipine and since I am still on the medication, it continues, but is not severe enough to give up the solution to migraines. I used to exercise on a good routine before migraines set in, but after a year before finding a solution, I lost the routine, gained 20 pounds back (I'd lost 40 over the previous couple of years), and lack motivation to get back to it. Depression has come back--I've battled it since childhood-- and returned to using desipramine after trying just about everything else. It's not as bad, but I attribute the weight gain and lack of motivation to depression. I'm currently taking 100 mg and can tell improvement, but broke down in odd crying spell at Church service yesterday for no real reason--just touched, but tears wouldn't stop. The neurontin was supposed to help with fatigue, but I tried to taper off and found my mind racing at night so went back on it; I definitely talk and walk in my sleep on it--taking 1600 mg at night.

    Reply

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More reviews for: Gabapentin, Depression

On eHealthMe, Gabapentin (gabapentin) is often used for pain. Find out below the conditions Gabapentin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Gabapentin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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