Review: could Gabapentin cause Depression?


Summary

Depression is found among people who take Gabapentin, especially for people who are female, 50-59 old , have been taking the drug for 1 - 6 months, also take medication Zometa, and have Depression . We study 51,418 people who have side effects while taking Gabapentin from FDA and social media. Among them, 1,950 have Depression. Find out below who they are, when they have Depression and more.

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Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Gabapentin 83,499 users)

Depression

Depression has been reported by people with suicidal ideation, pain, drug ineffective, insomnia, fatigue (latest reports from 355,810 Depression patients).

On Sep, 15, 2016

51,418 people reported to have side effects when taking Gabapentin.
Among them, 1,950 people (3.79%) have Depression


Number of reports submitted per year:

Could Gabapentin cause Depression?

Time on Gabapentin when people have Depression *:

  • < 1 month: 25.24 %
  • 1 - 6 months: 27.67 %
  • 6 - 12 months: 14.56 %
  • 1 - 2 years: 11.17 %
  • 2 - 5 years: 13.59 %
  • 5 - 10 years: 6.31 %
  • 10+ years: 1.46 %

Gender of people who have Depression when taking Gabapentin *:

  • female: 63.32 %
  • male: 36.68 %

Age of people who have Depression when taking Gabapentin *:

  • 0-1: 0.06 %
  • 2-9: 0.19 %
  • 10-19: 0.9 %
  • 20-29: 3.68 %
  • 30-39: 10.9 %
  • 40-49: 22.82 %
  • 50-59: 31.98 %
  • 60+: 29.46 %

Severity if Depression when taking Gabapentin **:

  • least: 4.76 %
  • moderate: 44.44 %
  • severe: 39.68 %
  • most severe: 11.11 %

How people recovered from Depression **:

  • while on drug: 2.27 %
  • after off the drug: 29.55 %
  • not yet: 68.18 %

Top conditions involved for these people *:

  • Depression (333 people, 17.08%)
  • Pain (316 people, 16.21%)
  • Multiple Sclerosis (204 people, 10.46%)
  • Anxiety (203 people, 10.41%)
  • Hypertension (175 people, 8.97%)

Top co-used drugs for these people *:

  • Zometa (332 people, 17.03%)
  • Cymbalta (289 people, 14.82%)
  • Neurontin (255 people, 13.08%)
  • Aspirin (254 people, 13.03%)
  • Lyrica (237 people, 12.15%)

Top other side effects for these people *:

  • Anxiety (725 people, 37.18%)
  • Pain (625 people, 32.05%)
  • Fatigue (442 people, 22.67%)
  • Nausea (372 people, 19.08%)
  • Insomnia (357 people, 18.31%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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