Gabapentin and Serotonin syndrome - from FDA reports


Summary

Serotonin syndrome is found among people who take Gabapentin, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Fentanyl, and have Pain . We study 83,679 people who have side effects while taking Gabapentin from FDA. Among them, 283 have Serotonin syndrome. Find out below who they are, when they have Serotonin syndrome and more.

What to expect?

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Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. (latest outcomes from Gabapentin 89,164 users)

Serotonin Syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, insomnia (latest reports from 9,744 Serotonin syndrome patients).

On Feb, 02, 2017

83,679 people reported to have side effects when taking Gabapentin.
Among them, 283 people (0.34%) have Serotonin Syndrome


Number of reports submitted per year:

Could Gabapentin cause Serotonin syndrome?

Time on Gabapentin when people have Serotonin Syndrome *:

  • < 1 month: 81.25 %
  • 1 - 6 months: 6.25 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 12.5 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Serotonin Syndrome when taking Gabapentin *:

  • female: 66.04 %
  • male: 33.96 %

Age of people who have Serotonin Syndrome when taking Gabapentin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.84 %
  • 20-29: 6.28 %
  • 30-39: 19.67 %
  • 40-49: 22.59 %
  • 50-59: 16.74 %
  • 60+: 33.89 %

Top conditions involved for these people *:

  • Pain (94 people, 33.22%)
  • Depression (81 people, 28.62%)
  • Neuralgia (36 people, 12.72%)
  • Muscle Spasms (15 people, 5.30%)
  • Anaesthesia (15 people, 5.30%)

Top co-used drugs for these people *:

  • Fentanyl (37 people, 13.07%)
  • Ondansetron (36 people, 12.72%)
  • Omeprazole (34 people, 12.01%)
  • Cymbalta (32 people, 11.31%)
  • Clonazepam (31 people, 10.95%)

Top other side effects for these people *:

  • Confusional State (51 people, 18.02%)
  • Tremor (34 people, 12.01%)
  • Arrhythmias (31 people, 10.95%)
  • Agitation (29 people, 10.25%)
  • Fever (27 people, 9.54%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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