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Review: could Gabapentin cause Tardive dyskinesia?

Summary: Tardive dyskinesia could be caused by Gabapentin, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take Metoclopramide, and have Gastrooesophageal reflux disease.

We study 36,656 people who have side effects while taking Gabapentin from FDA and social media. Among them, 151 have Tardive dyskinesia. Find out below who they are, when they have Tardive dyskinesia and more.

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Gabapentin

Gabapentin (latest outcomes from 39,166 users) has active ingredients of gabapentin. It is often used in pain.

Tardive dyskinesia

Tardive dyskinesia (a disorder that involves involuntary movements) (latest reports from 92,476 patients) has been reported by people with indigestion, abdominal distension, bipolar disorder, depression, gastrointestinal disorder.

On Apr, 10, 2014: 36,743 people reported to have side effects when taking Gabapentin. Among them, 151 people (0.41%) have Tardive Dyskinesia. They amount to 0.16% of all the 92,428 people who have Tardive Dyskinesia on eHealthMe.

Trend of Tardive dyskinesia in Gabapentin reports

Time on Gabapentin when people have Tardive dyskinesia * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Tardive dyskinesia33.33%0.00%66.67%0.00%0.00%0.00%0.00%

Age of people who have Tardive dyskinesia when taking Gabapentin * :

0-12-910-1920-2930-3940-4950-5960+
Tardive dyskinesia0.00%0.00%1.75%1.75%0.88%26.32%21.93%47.37%

Severity of Tardive dyskinesia when taking Gabapentin ** :

n/a

How people recovered from Tardive dyskinesia ** :

n/a

Top conditions involved for these people * :

  1. Gastrooesophageal reflux disease (45 people, 29.80%)
  2. Bipolar disorder (17 people, 11.26%)
  3. Anxiety (14 people, 9.27%)
  4. Psychotic disorder (13 people, 8.61%)
  5. Affective disorder (12 people, 7.95%)

Top co-used drugs for these people * :

  1. Metoclopramide (71 people, 47.02%)
  2. Nexium (49 people, 32.45%)
  3. Lipitor (43 people, 28.48%)
  4. Aspirin (37 people, 24.50%)
  5. Omeprazole (36 people, 23.84%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Gabapentin, Tardive dyskinesia

You can also:

On eHealthMe, Gabapentin (gabapentin) is often used for pain. Find out below the conditions Gabapentin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Gabapentin used for and how effective is it:

Other drugs that are used to treat the same conditions:

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Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (13 months ago):

  • Kevin Peters Ph.d on Mar, 4, 2013:

    Sammy, I'm a white 45 male; just wanted to agree on that Klonopin remark. When I was 21 I had my second kidney transplant which was a BAD issue all together, at any rate the hospital did not include my medications taken at home after my surgery. I went thru the worst hallucinations and jerking and seizures you could ever possibly imagine. This went on for almost 3 1/2 weeks before we decided to have me taken OUT of the hospital and relocated before they ended up taking my life. Then the whole staff of paychology including the chief of psychiatry cane in my room to see what they could do, Finallu. During one of my few moments of clarity the C.O.F after blaming me if talking "drugs" prior to my transplant listened to my word of telling him the meds I was on before being admitted. After asking when was the last time I had received my Klonopin and me not knowing, he then reviewed the charts, and didn't see me receiving this med once. He stormed out of the room of about 9 docs and came back in with two Klonopin; for the first time in almost 4 weeks and after three surgeries the first 72 hours I was hospitalized, I was sleeping like a baby, for about 49 hours with NO MORE hallucinations, or seizures or jerking! I finally got out of there without a kidney since that kidney was supposed to go to another man named the same as I in a different city! I do take Xanax and probably always will. The half life on Klonopin is much different hence one if its dangers, Nevwr Ever stop this drug cold! I've been on dialysis 25 1/2 years now and suffered from intense skin cancers, but have fought and done all I can do to live a normal as possible life, working full time except when I'm in yet another surgery, over 32 general anesthetic procedures since 1987. I was the youngest boy-man to ever be on the USA soccer team ready to play in the Korea 1988 Olympics. What a change in life.....
    All the Best,
    K. Peters

    Reply

    chris on Jun, 4, 2011:

    i have been taking clonzepam and trazedone and my speech is a very hoarse voice, I am wondering if if my speech problem is from these drugs's side effects.

    Reply

    TwoDimes on Apr, 15, 2012:

    Upon occasion, I, too, have become hoarse and from the use of Klonopin. I was VERY hoarse when I tried to cold turkey off of 4mgs of Klonopin. I am now down to 1.5mgs per day and, still, (as I said, upon occasion, I become hoarse. I am sure that the use of Klonopin is the causative factor. - TwoDimes -

    Reply

    SammySushi on Jul, 10, 2012:

    Omigosh, never cold turkey clonopin, esp that high of a dose. My dad had a major seizure and hallucinations doing so.

    Reply

    Christophe on Nov, 13, 2012:

    Hello,
    I suffer from Hypothyroidism, High Cholesterol & Cancer survivor because of Zyprexa use and previously being prescribed Carbamezapine causing Thyroid damage. My best advice to you if you don't want Hypothyroidism is have regular blood tests, Thyroid damage can be undetected for up to 5 years with no symptoms found on regular blood tests prematurally. Make sure you buy iodised salt to use on food when eating this will help reduce your risk of getting Hypothyroidism. two signs of Hypothyriodism which the Carbamezapine & Zyprexa medication boxes labels wont tell you is if your face becomes puffed up, red or sun sensitive while taking these medications this is a sign of Hypothyroidism. It wont be found on your blood test but later on it could appear out of the blue. The other sign to look for is baldness or hair loss on your head, this is another symptom. I hope these comments will help you. You have to weight up the benefits and negatives taking medications if you decide to take these medicines or not. It depends on how you cope with the drug side effects.
    from Christophe

    Reply

    AUDREY on Dec, 16, 2012:

    STARTED TAKING DILTIAZEM 60 MG AND I AM VERY CONSTIPATED. 70 YEARS OLD, HEART SURGERY A FAST HEART RATE....

    Reply

    Sonya on Feb, 24, 2013:

    You definately need to take a stool softener...straining during defication can cause major problems in people with cardiac problems.

    Reply

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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- Gabapentin side effects

 

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- Tardive Dyskinesia

 

 

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