Review: could Gentamicin cause Clostridium Difficile Colitis?


Summary

Clostridium difficile colitis is found among people who take Gentamicin, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Metronidazole, and have Pneumonia . We study 7,436 people who have side effects while taking Gentamicin from FDA and social media. Among them, 37 have Clostridium difficile colitis. Find out below who they are, when they have Clostridium difficile colitis and more.

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Gentamicin

Gentamicin has active ingredients of gentamicin sulfate. It is often used in endocarditis. (latest outcomes from Gentamicin 10,360 users)

Clostridium Difficile Colitis

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) has been reported by people with death, drug ineffective, agranulocytosis, abdominal pain, disease recurrence (latest reports from 5,907 Clostridium difficile colitis patients).

On Sep, 18, 2016

7,436 people reported to have side effects when taking Gentamicin.
Among them, 37 people (0.5%) have Clostridium Difficile Colitis


Number of reports submitted per year:

Could Gentamicin cause Clostridium difficile colitis?

Time on Gentamicin when people have Clostridium Difficile Colitis *:

  • < 1 month: 84.21 %
  • 1 - 6 months: 15.79 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Clostridium Difficile Colitis when taking Gentamicin *:

  • female: 40.54 %
  • male: 59.46 %

Age of people who have Clostridium Difficile Colitis when taking Gentamicin *:

  • 0-1: 5.88 %
  • 2-9: 2.94 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 11.76 %
  • 50-59: 26.47 %
  • 60+: 52.94 %

Top conditions involved for these people *:

  • Pneumonia (7 people, 18.92%)
  • Urine Output Decreased (6 people, 16.22%)
  • Prophylaxis (6 people, 16.22%)
  • Insomnia (6 people, 16.22%)
  • Clostridial Infection (4 people, 10.81%)

Top co-used drugs for these people *:

  • Metronidazole (14 people, 37.84%)
  • Morphine (10 people, 27.03%)
  • Omeprazole (9 people, 24.32%)
  • Ipratropium Bromide (9 people, 24.32%)
  • Albuterol (9 people, 24.32%)

Top other side effects for these people *:

  • Septic Shock (10 people, 27.03%)
  • Renal Failure (9 people, 24.32%)
  • Pneumonia (8 people, 21.62%)
  • Convulsion (8 people, 21.62%)
  • Pulmonary Oedema (7 people, 18.92%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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