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Review: could Gleevec cause Nephrolithiasis (Kidney stones)?





Summary: Nephrolithiasis is found among people who take Gleevec, especially for people who are male, 10-19 old, have been taking the drug for 1 - 6 months, also take medication Methotrexate, and have Prophylaxis.

We study 20,254 people who have side effects while taking Gleevec from FDA and social media. Among them, 84 have Nephrolithiasis. Find out below who they are, when they have Nephrolithiasis and more.

You are not alone: join a mobile support group for people who take Gleevec and have Nephrolithiasis >>>

Gleevec

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). (latest outcomes from Gleevec 20,439 users)

Nephrolithiasis

Nephrolithiasis (calculi in the kidneys) has been reported by people with multiple sclerosis, osteoporosis, high blood pressure, rheumatoid arthritis, pain.(latest reports from Nephrolithiasis 14,308 patients)

On Nov, 28, 2014: 20,254 people reported to have side effects when taking Gleevec. Among them, 84 people (0.41%) have Nephrolithiasis.

Trend of Nephrolithiasis in Gleevec reports

Time on Gleevec when people have Nephrolithiasis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Nephrolithiasis18.18%45.45%18.18%0.00%9.09%9.09%0.00%

Gender of people who have Nephrolithiasis when taking Gleevec * :

FemaleMale
Nephrolithiasis22.79%77.21%

Age of people who have Nephrolithiasis when taking Gleevec * :

0-12-910-1920-2930-3940-4950-5960+
Nephrolithiasis0.00%0.00%46.05%1.32%7.89%17.11%15.79%11.84%

Severity of Nephrolithiasis when taking Gleevec ** :

n/a

How people recovered from Nephrolithiasis ** :

n/a

Top conditions involved for these people * :

  1. Prophylaxis (35 people, 41.67%)
  2. Chronic myeloid leukaemia (33 people, 39.29%)
  3. Gastrointestinal stromal tumour (10 people, 11.90%)
  4. Osteoporosis (10 people, 11.90%)
  5. Malignant soft tissue neoplasm (9 people, 10.71%)

Top co-used drugs for these people * :

  1. Methotrexate (35 people, 41.67%)
  2. Zantac (35 people, 41.67%)
  3. Mercaptopurine (35 people, 41.67%)
  4. Bactrim (35 people, 41.67%)
  5. Cyclophosphamide (35 people, 41.67%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Nephrolithiasis while taking Gleevec?

You are not alone! Join a mobile support group:
- support group for people who take Gleevec and have Nephrolithiasis
- support group for people who take Gleevec
- support group for people who have Nephrolithiasis

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