Review: could Gleevec cause Nephrolithiasis?


Summary

Nephrolithiasis is found among people who take Gleevec, especially for people who are male, 40-49 old , have been taking the drug for 1 - 6 months, also take medication Zometa, and have Chronic myeloid leukaemia . We study 24,330 people who have side effects while taking Gleevec from FDA and social media. Among them, 117 have Nephrolithiasis. Find out below who they are, when they have Nephrolithiasis and more.

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Gleevec

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). (latest outcomes from Gleevec 25,077 users)

Nephrolithiasis

Nephrolithiasis (calculi in the kidneys) has been reported by people with multiple sclerosis, osteoporosis, rheumatoid arthritis, high blood pressure, crohn's disease (latest reports from 22,991 Nephrolithiasis patients).

On Nov, 26, 2016

24,330 people reported to have side effects when taking Gleevec.
Among them, 117 people (0.48%) have Nephrolithiasis


Number of reports submitted per year:

Could Gleevec cause Nephrolithiasis?

Time on Gleevec when people have Nephrolithiasis *:

  • < 1 month: 25.0 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 8.33 %
  • 1 - 2 years: 8.33 %
  • 2 - 5 years: 8.33 %
  • 5 - 10 years: 8.33 %
  • 10+ years: 8.33 %

Gender of people who have Nephrolithiasis when taking Gleevec *:

  • female: 35.09 %
  • male: 64.91 %

Age of people who have Nephrolithiasis when taking Gleevec *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 5.77 %
  • 20-29: 3.85 %
  • 30-39: 9.62 %
  • 40-49: 30.77 %
  • 50-59: 21.15 %
  • 60+: 28.85 %

Top co-used drugs for these people *:

  • Zometa (18 people, 15.38%)
  • Rocephin (12 people, 10.26%)
  • Compazine (12 people, 10.26%)
  • Aredia (12 people, 10.26%)
  • Singulair (11 people, 9.40%)

Forecasts by ePatient.care (You can know it earlier! Forecast new symptoms and undetected conditions when you take Gleevec, learn more)

Potential co-existing conditions

  • Chronic Myeloid Leukaemia (47 people, 40.17%)
  • Osteoporosis (11 people, 9.40%)
  • Gastrointestinal Stromal Tumour (9 people, 7.69%)

Potential co-existing symptoms

  • Nausea (30 people, 25.64%)
  • Fatigue (28 people, 23.93%)
  • Pain (25 people, 21.37%)
  • Back Pain (24 people, 20.51%)
  • Diarrhea (22 people, 18.80%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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