Review: could Humira cause Osteoarthritis?
Summary: Osteoarthritis is found among people who take Humira, especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years, also take medication Methotrexate, and have Rheumatoid arthritis.
We study 136,021 people who have side effects while taking Humira from FDA and social media. Among them, 784 have Osteoarthritis. Find out below who they are, when they have Osteoarthritis and more.
You are not alone: join a mobile support group for people who take Humira and have Osteoarthritis >>>
Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. (latest outcomes from 136,734 Humira users)
Osteoarthritis (a joint disease caused by cartilage loss in a joint) has been reported by people with osteoporosis, osteopenia, rheumatoid arthritis, high blood pressure, pain. (latest reports from 35,027 Osteoarthritis patients)
On Jan, 31, 2015: 136,006 people reported to have side effects when taking Humira. Among them, 784 people (0.58%) have Osteoarthritis.
Time on Humira when people have Osteoarthritis * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Gender of people who have Osteoarthritis when taking Humira * :
Age of people who have Osteoarthritis when taking Humira * :
Severity of Osteoarthritis when taking Humira ** :
How people recovered from Osteoarthritis ** :
Top conditions involved for these people * :
- Rheumatoid arthritis (736 people, 93.88%)
- Hypertension (205 people, 26.15%)
- Pain (189 people, 24.11%)
- Psoriatic arthropathy (132 people, 16.84%)
- Vitamin supplementation (95 people, 12.12%)
Top co-used drugs for these people * :
- Methotrexate (376 people, 47.96%)
- Folic acid (207 people, 26.40%)
- Prednisone (179 people, 22.83%)
- Aspirin (83 people, 10.59%)
- Celebrex (83 people, 10.59%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Do you have Osteoarthritis while taking Humira?
You are not alone! Join a mobile support group:
- support group for people who take Humira and have Osteoarthritis
- support group for people who take Humira
- support group for people who have Osteoarthritis
Drugs in real world that are associated with:
Could your condition cause:
Can you answer these questions (Ask a question):
- Is it safe to take biotin and humira to gether?
I would like to add biotin to my daily med. schedule. I want to make sure there are no interactions
- Is it safe to take zocalo if you are taking humora and methotrexate
Is it safe to take all three of these together? I need to know if there is any adverse side effects of taking these drugs at the same time?
- Does humira cause bad common warts and how to get rid of them, tried dcp treatment, still the same
really bad warts on hands, have tried wart off and been to dermatologist and been using dcp treatment, no change to warts
- Does anyone experience heart palpitations causedby their acid reflux ? (2 answers)
I have had acid reflux/Gerd for 4 years + Was not believed that symptoms were real for a while as had no heartburn and a diagnosis of Fibromyalgia which even now some medics think is imaginary...it's NOT!!! Following a demeester score of 45 ( very high confirmation of acid reflux) and discovery of a large hiatal hernia, ( a classic physical cause of acid reflux) I had hernia repair operation and LINX anti reflux surgery. Throughout the four years a major symptom of my acid reflux were heart palpatations. They started at the same time I started with reflux and cleared up after the surgery. I have been reflux free palpitation free and antacid free for four months. then I was put on Gabapentin for back spasm and the reflux returned along with the palpitations. Medics keep insisting this is just anxiety yet eat a food that gives me reflux also starts the palps which is the indicator of the reflux as I do not have heartburn. Comes on when relaxing and eating watching tv ( no anxiety present) and when I am sleeping peacefully ( no anxiety present) my heart wakes me up and fires off into tachycardia. Recently a doctor has said it is now known that acid reflux irritates the nerves in the solar plexus area and that triggers the palps. Anyone else experienced this? Are there any studies on it at all? Thanks all.
- Is there a support group in the us for people with insulinomas? (1 answer)
SUPPORT GROUP IN UNITED STATES!!!
Hi, the only support group that I've been able to find for people with insulinomas is located in the UK... just wondering if there is one in the US. I had pancreatic surgery to remove my first insulinoma in 2012, we're thinking there's another because I'm still having problems with hypoglycemia... if anyone know anything, PLEASE CONTACT ME!!! :)
I know there can't just be a support group here for FERRETS!!! people are kind of important... I hate this song, but "Don't worry, BE HAPPY" is okay, I guess... I'm trying to force it upon myself. Things will get BETTER!!!
More questions for: Humira, Osteoarthritis
You may be interested at these reviews (Write a review):
- My friend died of sepsis while having taken humera for a year.
My friend said she didn't feel good but was still active until about 20 hours before her death in the ICU on a ventilator from sepsis. She was just 55. This is a horror story. People are devastated.
- Had nms in 2005, will trileptal increase chance of recurrence?
In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
- Humira: my experience
I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.
I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(
I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.
I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.
My MD is going to get me onto another injectable that I take monthly. I forget its name.
- Sepsis hallucinations misdiagnosed
I was admitted to the hospital at 10 p.m., with a total bowel blockage caused by scar-tissue adhesions. I had first gone to the ER at 3 a.m. that morning, but the ER doc misdiagnosed my condition as constipation. I was in extreme pain and also too weak to tell my husband when he first came home that I needed to return to the ER. By the time I returned, I became violently nauseated, and vomited repeatedly. Then a gastro-nasal tube was forced down my nose and into my stomach. I began hallucinating at approximately 5 p.m. the following day. I did not realize I was hallucinating, and thought my experiences were real. Some were quite coherent, such as believing there was a book sitting on table at home with a photo on the front showing a sculpture in white marble of a woman's hands holding the Bible, with barbed wire wrapped around her hands. I thought the sculpture had won the Nobel prize, and the book was the biography of the sculptor, whose mother had gone to extraordinary lengths to keep him safe from the Nazis. Some may actually have occurred during dreams, and were wildly improbable, but I don't recall ever going to sleep. At one point, I thought I was at a rest stop on the NJ turnpike, and saw the Nobel-winning sculptor there, working on a wood sculpture. The sculptor turned out to be the maintenance man on the hospital floor. I pulled out the naso-gastral tube three times, but was unaware that I had done so, although I do remember believing that I was buried beneath peat moss and feeling suffocated as I clawed my way out. I also thought I was at a party being given by a law firm which had sold its building to a school for gifted children, but I (also a lawyer) had been deposited there by my nurse and her boyfriend, who were supposed to have taken me to the OR. Some scenes from a book I had been reading made their way into my delusions, which were so real to me that I actually called some of the people involved later on and asked if the events had really happened. The hallucinations began before surgery and continued afterward. When I awoke from anesthesia, I thought the hospital staff was painting the doors to my upstairs bathroom, a project I'd been involved with before the blockage struck. I asked them how they knew what colors to use. They thought I was joking, and confirmed that they had gotten the colors right. Finally a neurologist was summoned, and I told her I was on the passenger ramp at La Guardia airport (instead of in a hospital in NC), and that I'd been born in Havana, Cuba (instead of Baltimore, MD.) I believed myself to be a member of the ruling party in Cuba (pre-Castro) and during an outdoor ceremony, an earthquake had struck, causing ancient monuments to come tumbling down. Later, I was bobbing in harbor waters near a huge ocean liner, with plastic bottles and other detritus floating by. The foregoing are only a small sample of the multitude of hallucinations. Occasionally, I was only an observer of astonishing events, but usually I was a participant. I recognized my husband and friends, but told them about many of these events, believing they had happened. The neurologist diagnosed clonazepam withdrawal. My other doctors later said this was unlikely, as I took clonazepam in small amounts on an erratic schedule, and was not dependent on the drug, although my prescription called for 3 mg. daily. Physician friends said my symptoms were more likely the result of sepsis. I did contract a urinary-tract infection from the catheter, and was being given antibiotics. Additionally, the nature of my underlying condition, and the delay in diagnosis and treatment, may have contributed to the sepsis. Hallucinations occur in only a very small percentage of sepsis sufferers, and in only a small percentage of those withdrawing suddenly from clonazepam. However, I do fit the profile of those who do experience hallucinations with sepsis, being female and aged 62 at the time of this description. After the three-day period, I returned to normal, although believing that my hallucinations had been real persisted for some days afterward. I recovered quickly from the surgery, although the pain persisted for a while, and I was walking easily (dragging my IV with me) through the hospital halls. This was the ONLY symptom I had. Not all the hallucinations were unpleasant -- in fact, they were highly interesting -- but they were incredibly complex. I still remember all the details, better than I remember what actually happened yesterday. Except for the urinary-tract infection, I had no other adverse effects from hospitalization -- no fever, chills, nausea, sweating, headaches, trembling or anything of that kind. The bowel blockage and the surgery were of course not fun, but in a way the hallucinations were fascinating. My own feeling, and that of the doctors who know me and my medical issues, is that my experiences were caused by sepsis, not clonazepam withdrawal, and the antibiotics I was given are probably what saved me.
- Non effective for pain effective for positive nausea (1 response)
Have been taking this product for a little over a month and the nausea is getting worse but the pain is not. This seems to be causing more problems. This side effect occurs with or without food, and with or without a full glass of water.
More reviews for: Humira, Osteoarthritis
Comments from related studies:
From this study (2 years ago):
VickiL on Jul, 8, 2011:
Let me be the 1st female to develop osteoarthritis while taking interferon treatments. I have been off treatments since 5/27/2011, and my pain keeps getting worse. Joints are freezing up, I can hardly walk or use my hands at times. No pain in back or hips, just feet, hands knees, & shoulders. I hate to say this, but had I known it would be this bad, I think I would have taken my chances with the hepatitis c. My GP is treating me with NSAIDS, but they don't seem to be working. Where do I go from here?
Kim on Oct, 2, 2012:
Vicki I am so sorry to read about what you have been through. I just finished my Intron treatment about a week ago. The arthritis symptoms have started for me also and they are severe. I wondered if your doctors have found anything that helps. I am having a hard time finding information which I am sure you already know. Since we seem to be two of a kind I would love to hear from you. I hope that you are doing better and feeling a little better. You can contact me on this thread. I am looking forward to hearing from you.
Cass on Nov, 7, 2012:
Vickil and Kim, You are not alone; I stopped taking inteferon and ribasphere on 6/23/12. After experiencing severe joint and muscle pain all over, I tested positive for rheumatoid arthritis in late September. I am being referred to a rheumatologist. RA has been identified as a potential side effect of inteferon. I pray relief for all sufferers of this condition.
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