Humira and Withdrawal syndrome - from FDA reports


Summary

Withdrawal syndrome is found among people who take Humira, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Methotrexate, and have Pain . We study 358,739 people who have side effects while taking Humira from FDA. Among them, 68 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.

What to expect?

If you take Humira and have Withdrawal syndrome, find out what symptoms you could have in 1 year or longer.

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Humira

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. (latest outcomes from Humira 360,599 users)

Withdrawal Syndrome

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, back pain, muscle spasticity (latest reports from 13,481 Withdrawal syndrome patients).

On Feb, 11, 2017

358,739 people reported to have side effects when taking Humira.
Among them, 68 people (0.02%) have Withdrawal Syndrome


Number of reports submitted per year:

Could Humira cause Withdrawal syndrome?

Time on Humira when people have Withdrawal Syndrome *:

  • < 1 month: 15.38 %
  • 1 - 6 months: 38.46 %
  • 6 - 12 months: 23.08 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 7.69 %
  • 5 - 10 years: 15.38 %
  • 10+ years: 0.0 %

Gender of people who have Withdrawal Syndrome when taking Humira *:

  • female: 65.15 %
  • male: 34.85 %

Age of people who have Withdrawal Syndrome when taking Humira *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.25 %
  • 20-29: 16.67 %
  • 30-39: 20.83 %
  • 40-49: 8.33 %
  • 50-59: 22.92 %
  • 60+: 25.0 %

Top conditions involved for these people *:

  • Pain (20 people, 29.41%)
  • Crohn's Disease (18 people, 26.47%)
  • Rheumatoid Arthritis (15 people, 22.06%)
  • Depression (12 people, 17.65%)
  • Psoriasis (8 people, 11.76%)

Top co-used drugs for these people *:

  • Methotrexate (13 people, 19.12%)
  • Lyrica (11 people, 16.18%)
  • Celebrex (7 people, 10.29%)
  • Xanax (6 people, 8.82%)
  • Fluoxetine (6 people, 8.82%)

Top other side effects for these people *:

  • Feeling Abnormal (16 people, 23.53%)
  • Diarrhea (15 people, 22.06%)
  • Depression (15 people, 22.06%)
  • Pain (14 people, 20.59%)
  • Dizziness (14 people, 20.59%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Withdrawal syndrome when taking Humira?

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