Review: could Humira cause Withdrawal syndrome?
Summary: Withdrawal syndrome is found among people who take Humira, especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months, also take medication Lyrica, and have Pain.
We study 136,021 people who have side effects while taking Humira from FDA and social media. Among them, 24 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.
You are not alone: join a mobile support group for people who take Humira and have Withdrawal syndrome >>>
Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. (latest outcomes from 136,734 Humira users)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, muscle spasticity, back pain. (latest reports from 9,228 Withdrawal syndrome patients)
On Feb, 11, 2015: 136,006 people reported to have side effects when taking Humira. Among them, 24 people (0.02%) have Withdrawal Syndrome.
Time on Humira when people have Withdrawal syndrome * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Withdrawal syndrome||0.00%||50.00%||16.67%||0.00%||0.00%||33.33%||0.00% |
Gender of people who have Withdrawal syndrome when taking Humira * :
|Withdrawal syndrome||75.00%||25.00% |
Age of people who have Withdrawal syndrome when taking Humira * :
|Withdrawal syndrome||0.00%||0.00%||0.00%||15.00%||45.00%||10.00%||25.00%||5.00% |
Severity of Withdrawal syndrome when taking Humira ** :
How people recovered from Withdrawal syndrome ** :
Top conditions involved for these people * :
- Pain (14 people, 58.33%)
- Depression (8 people, 33.33%)
- Ankylosing spondylitis (6 people, 25.00%)
- Rheumatoid arthritis (6 people, 25.00%)
- Acne (4 people, 16.67%)
Top co-used drugs for these people * :
- Lyrica (10 people, 41.67%)
- Methotrexate (7 people, 29.17%)
- Gabapentin (5 people, 20.83%)
- Neurontin (5 people, 20.83%)
- Triamhexal (5 people, 20.83%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Do you have Withdrawal Syndrome while taking Humira?
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- support group for people who take Humira and have Withdrawal Syndrome
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- support group for people who have Withdrawal Syndrome
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You may be interested at these reviews (Write a review):
- My friend died of sepsis while having taken humera for a year.
My friend said she didn't feel good but was still active until about 20 hours before her death in the ICU on a ventilator from sepsis. She was just 55. This is a horror story. People are devastated.
- Lorazepam nearly killed me during cancer treatment
Day 31 of cold turkey and I want to die. It is a roller coaster from body tics and sweats to rage and crying in one day. I felt so good the 4h day of c/t. It was like before my cancer diagnosis. My bowels are better off Lorazepam. I threw up during bowel movements from the pain. Off Lorazepam first normal bowel movement in over 2 years. Stomach so damaged by Lorazepam that I have absolutely no appetite. I force myself to eat. Neuropathy in hands nearly gone. Feet are better but slower. Lymphedema that appeared after one year on Lorazepam is now gone. I have full range of motion.
- Humira: my experience
I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.
I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(
I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.
I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.
My MD is going to get me onto another injectable that I take monthly. I forget its name.
- Transient global amnesia
Having been on Humira for 12 months with full clearing of all symptoms of severe plaque psoriasis, I am a little unnerved by this episode. I was out clearing a substantial amount of snow from one of our decks. I remember being at the half way mark, and the next thing I remember is being on the way to emerge with my husband. Apparently we were in for lunch, and I lost focus when I went to the kitchen to make apot of tea. I commented on something I had taken out for dinner, but thought he had done so. He started to question me About the previous two days in which we had had a house full of company, and I didn't recall any of it. I now recall all of the weekend, but have no recollection of about a two and a half hour period prior to the arrival at emerg. Now, one day later, that memory is still non existent.
More reviews for: Humira, Withdrawal syndrome
Comments from related studies:
From this study (1 week ago):
motoboy on Jan, 29, 2015:
I've recently stopped taking ibuprofen after many years of taking it daily. I take between 800 to 1500 mg a day, mostly before bed to sleep. I have had a lot of sport injuries do it was for joint pain. It's been about a week since taking any and I'm getting really bad headaches. Can't seem to find this as a withdrawal issue... any one else experience this? Thanks!
From this study (2 weeks ago):
Bloody mucus from nose, head hurt worse when bending.....just all round sick
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