Review: could Humira cause Withdrawal syndrome?
Summary: Withdrawal syndrome is found among people who take Humira, especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months, also take medication Lyrica, and have Pain.
We study 135,973 people who have side effects while taking Humira from FDA and social media. Among them, 24 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.
You are not alone: join a mobile support group for people who take Humira and have Withdrawal syndrome >>>
Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. (latest outcomes from Humira 136,693 users)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, muscle spasticity, back pain.(latest reports from Withdrawal syndrome 9,186 patients)
On Dec, 12, 2014: 135,973 people reported to have side effects when taking Humira. Among them, 24 people (0.02%) have Withdrawal Syndrome.
Time on Humira when people have Withdrawal syndrome * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Withdrawal syndrome||0.00%||50.00%||16.67%||0.00%||0.00%||33.33%||0.00% |
Gender of people who have Withdrawal syndrome when taking Humira * :
|Withdrawal syndrome||75.00%||25.00% |
Age of people who have Withdrawal syndrome when taking Humira * :
|Withdrawal syndrome||0.00%||0.00%||0.00%||15.00%||45.00%||10.00%||25.00%||5.00% |
Severity of Withdrawal syndrome when taking Humira ** :
How people recovered from Withdrawal syndrome ** :
Top conditions involved for these people * :
- Pain (14 people, 58.33%)
- Depression (8 people, 33.33%)
- Ankylosing spondylitis (6 people, 25.00%)
- Rheumatoid arthritis (6 people, 25.00%)
- Acne (4 people, 16.67%)
Top co-used drugs for these people * :
- Lyrica (10 people, 41.67%)
- Methotrexate (7 people, 29.17%)
- Gabapentin (5 people, 20.83%)
- Neurontin (5 people, 20.83%)
- Triamhexal (5 people, 20.83%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Withdrawal Syndrome while taking Humira?
You are not alone! Join a mobile support group:
- support group for people who take Humira and have Withdrawal Syndrome
- support group for people who take Humira
- support group for people who have Withdrawal Syndrome
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Could your condition cause:
Can you answer these questions (Ask a question):
- Can humira be stooped while herpes outbreak
(Asked by a 28 year old woman who has Blood Checkw For Herpes Level, and takes Humira)
I am waiting for blood results for herpes level screeing. I am worry that they will not give me humira or it will delay first injection. Do I wil have it anyway or if virus level is too high they will not give it to me?
- Does humira adversely interact with casodex
(Asked by a 71 year old man who has Prostate Cancer Recurrent, and takes Humira, Casodex)
Humira for ankalosing spondilytis and casodex for prostate cancer
- Has anyone had problems with blood work eg. elevated levels of lymphocytes?
(Asked by a 50 year old woman who has Ankylosing Spondylitis, and takes Vitamin D, Humira)
Had further blood work done and nothing showed up? tested for viral infections mono hiv cmv toxoplasmosis all neg. surface immunophenotyping by flow cytometry done nothing there any answers here?
- I am on humira and methotrexate for the last 6 years and have previously had oestomylelitis and i am now suffering with pain in the same ankle has anybody had a recurrence of bone infection whilst on (1 answer)
(Asked by a 54 year old woman who has Osteomyelitis Chronic, Psoriatic Arthritis, and takes Methotrexate, Humira)
I have been on Humira and Methotrexate for about 5 year's and have had previously had ostiomylius in my left Ankle . I have been suffering with pain and swelling in the same Ankle and I have had a bone scan which shows activity in the bone and I am waiting to hear what happens next but I have no fever so I am sort of hoping that it won't be a bone infection .So has anybody else had oestomylelitis with out a fever. Would be grateful for any feed back thankyou .
- Do all rheumatoid arthritis drugs cause shortness of breath or panic?
(Asked by a 68 year old woman who has Lung Disease - Rheumatoid Arthritis, and takes Enbrel, Humira, Methotrexate, Orencia)
Took methotrexate from 2007 until 2011 and caused shortness of breath. Switched to Humira, better on pain and then Enbrel. All caused shortness of breath and was hospitalized. I have lung damage and on oxygen 24/7. Taking infusion therapy, but get severe panic attacks. Can't tolerate the pain of RA, but medications side affects are even worse.
More questions for: Humira, Withdrawal syndrome
You may be interested at these reviews (Write a review):
- My friend died of sepsis while having taken humera for a year.
(Posted by a 50 year old woman who has Psoriasis, and takes Humira)
My friend said she didn't feel good but was still active until about 20 hours before her death in the ICU on a ventilator from sepsis. She was just 55. This is a horror story. People are devastated.
- Lorazepam nearly killed me during cancer treatment
(Posted by a 66 year old woman who has Insomnia, Bowel Movement Irregularity, Withdrawal Syndrome, and takes Wellbutrin Sr, Prozac, Lorazepam)
Day 31 of cold turkey and I want to die. It is a roller coaster from body tics and sweats to rage and crying in one day. I felt so good the 4h day of c/t. It was like before my cancer diagnosis. My bowels are better off Lorazepam. I threw up during bowel movements from the pain. Off Lorazepam first normal bowel movement in over 2 years. Stomach so damaged by Lorazepam that I have absolutely no appetite. I force myself to eat. Neuropathy in hands nearly gone. Feet are better but slower. Lymphedema that appeared after one year on Lorazepam is now gone. I have full range of motion.
- Humira: my experience
(Posted by a 66 year old man who has Ankylosing Spondylitis, Reiter's Syndrome, Psoriatic Arthritis, and takes Methotrexate Preservative Free, Enbrel, Humira)
I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.
I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(
I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.
I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.
My MD is going to get me onto another injectable that I take monthly. I forget its name.
- Transient global amnesia
(Posted by a 58 year old woman who has Transient Global Amnesia, and takes Humira)
Having been on Humira for 12 months with full clearing of all symptoms of severe plaque psoriasis, I am a little unnerved by this episode. I was out clearing a substantial amount of snow from one of our decks. I remember being at the half way mark, and the next thing I remember is being on the way to emerge with my husband. Apparently we were in for lunch, and I lost focus when I went to the kitchen to make apot of tea. I commented on something I had taken out for dinner, but thought he had done so. He started to question me About the previous two days in which we had had a house full of company, and I didn't recall any of it. I now recall all of the weekend, but have no recollection of about a two and a half hour period prior to the arrival at emerg. Now, one day later, that memory is still non existent.
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