Review: could Hydrochlorothiazide cause Frequent Headaches?


Frequent headaches is found among people who take Hydrochlorothiazide, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Lisinopril, and have Hypertension . We study 67,289 people who have side effects while taking Hydrochlorothiazide from FDA and social media. Among them, 2,882 have Frequent headaches. Find out below who they are, when they have Frequent headaches and more.

You are not alone

Join a support group for people who take Hydrochlorothiazide and have Frequent headaches >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. (latest outcomes from Hydrochlorothiazide 68,026 users)

Frequent Headaches

Frequent headaches has been reported by people with breathing difficulty, pain, chest pain, fatigue, stress and anxiety (latest reports from 209,297 Frequent headaches patients).

On Aug, 24, 2016

67,289 people reported to have side effects when taking Hydrochlorothiazide.
Among them, 2,882 people (4.28%) have Frequent Headaches

Number of reports submitted per year:

Could Hydrochlorothiazide cause Frequent headaches?

Time on Hydrochlorothiazide when people have Frequent Headaches *:

  • < 1 month: 24.21 %
  • 1 - 6 months: 17.89 %
  • 6 - 12 months: 11.58 %
  • 1 - 2 years: 14.74 %
  • 2 - 5 years: 15.79 %
  • 5 - 10 years: 9.47 %
  • 10+ years: 6.32 %

Gender of people who have Frequent Headaches when taking Hydrochlorothiazide *:

  • female: 72.91 %
  • male: 27.09 %

Age of people who have Frequent Headaches when taking Hydrochlorothiazide *:

  • 0-1: 0.04 %
  • 2-9: 0.08 %
  • 10-19: 0.51 %
  • 20-29: 0.89 %
  • 30-39: 5.13 %
  • 40-49: 16.95 %
  • 50-59: 26.36 %
  • 60+: 50.04 %

Severity if Frequent Headaches when taking Hydrochlorothiazide **:

  • least: 9.3 %
  • moderate: 58.14 %
  • severe: 25.58 %
  • most severe: 6.98 %

How people recovered from Frequent Headaches **:

  • while on drug: 0.0 %
  • after off the drug: 21.43 %
  • not yet: 78.57 %

Top conditions involved for these people *:

  • Hypertension (723 people)
  • Depression (259 people)
  • Pain (195 people)
  • Rheumatoid Arthritis (175 people)
  • Blood Cholesterol Increased (146 people)

Top co-used drugs for these people *:

  • Lisinopril (508 people)
  • Aspirin (427 people)
  • Atenolol (357 people)
  • Lipitor (290 people)
  • Synthroid (264 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Frequent headaches when taking Hydrochlorothiazide?

Browse all side effects of Hydrochlorothiazide

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Frequent headaches

Frequent headaches

Could your condition cause Frequent headaches

Frequent headaches

Can you answer these questions?

More questions for: Hydrochlorothiazide, Frequent headaches

You may be interested in these reviews

More reviews for: Hydrochlorothiazide, Frequent headaches

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.