Review: could Hydroxyurea cause Sickle cell anaemia with crisis?
Summary: Sickle cell anaemia with crisis is found among people who take Hydroxyurea, especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months, also take medication Exjade, and have Sickle cell anaemia.
We study 3,287 people who have side effects while taking Hydroxyurea from FDA and social media. Among them, 112 have Sickle cell anaemia with crisis. Find out below who they are, when they have Sickle cell anaemia with crisis and more.
You are not alone: join a mobile support group for people who take Hydroxyurea and have Sickle cell anaemia with crisis >>>
Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. (latest outcomes from 3,377 Hydroxyurea users)
Sickle cell anaemia with crisis
Sickle cell anaemia with crisis (sickle cell anaemia have painful episodes) has been reported by people with sickle cell anaemia, iron overload, pain, blood iron increased, constipation. (latest reports from 1,725 Sickle cell anaemia with crisis patients)
On Feb, 12, 2015: 3,287 people reported to have side effects when taking Hydroxyurea. Among them, 112 people (3.41%) have Sickle Cell Anaemia With Crisis.
Time on Hydroxyurea when people have Sickle cell anaemia with crisis * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Sickle cell anaemia with crisis||0.00%||100.00%||0.00%||0.00%||0.00%||0.00%||0.00% |
Gender of people who have Sickle cell anaemia with crisis when taking Hydroxyurea * :
|Sickle cell anaemia with crisis||68.18%||31.82% |
Age of people who have Sickle cell anaemia with crisis when taking Hydroxyurea * :
|Sickle cell anaemia with crisis||0.00%||1.15%||9.20%||29.89%||29.89%||22.99%||6.90%||0.00% |
Severity of Sickle cell anaemia with crisis when taking Hydroxyurea ** :
How people recovered from Sickle cell anaemia with crisis ** :
Top conditions involved for these people * :
- Sickle cell anaemia (57 people, 50.89%)
- Iron overload (34 people, 30.36%)
- Pain (19 people, 16.96%)
- Nausea (13 people, 11.61%)
- Pulmonary hypertension (10 people, 8.93%)
Top co-used drugs for these people * :
- Exjade (84 people, 75.00%)
- Folic acid (83 people, 74.11%)
- Oxycontin (16 people, 14.29%)
- Percocet (15 people, 13.39%)
- Dilaudid (14 people, 12.50%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Sickle Cell Anaemia With Crisis while taking Hydroxyurea?
You are not alone! Join a mobile support group:
- support group for people who take Hydroxyurea and have Sickle Cell Anaemia With Crisis
- support group for people who take Hydroxyurea
- support group for people who have Sickle Cell Anaemia With Crisis
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- Hydroxyurea and pomegranate juice
sorry for my bad english.
i am a retired physician, specialist in i.medicine & gastroenterology.
have essencial thrombocythemia since year 2000.
mild hypercholesterolemia once treated wiht symvastatin 20 mg/day.
during a certain time i began to take 100 cc of pomegranate juice/3 times per week. before that my platelets were +/- stable at 400-450.000 y also my cholesterol at normal.
after a few weeks of drinking pomegranate juice suddenly found: platelets fell to 300.000 and there was a leucopenia with absolute leucocytes count 1.7.
also the cholesterol ldl and total fell to levels that never had before. at this stage stoped pomegranate juice and stoped hydrea and after more or les normalization began again hydrea when al the blood values return to a normal or higher level.
I think that there is, probably, an interaction between hyderea and also smvastatin with pomegranate juice.
for an unrelated cause i stoped symvastatin a few months ago. no i have a problem again with platelets that are high (480.000) and leucopenia (perhaps myelofibrosis ?). since a week we lowered de hydrea and i again began taking 100 cc of pomegranate juice twice a week. i have an appointment to my hematologist in 4 weeks and will do blood tests.
alfredo leiser md, holon, israel
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Comments from related studies:
From this study (5 months ago):
starting chemotherapy, was told to get off hydroxurea before and during treatment. Started treatment 5 days ago and am suffering now. Major pain in chest wall lower back
From this study (5 months ago):
I am tired but my eyes seem to be darker underneath. I look like I do if I'm unwell. I eat well and I haven't had alcohol since April and I don't smoke. My bloods are due again this Thursday. I started on 2 tablets then went to 3 now I'm back on 2 as my bloods were low on last test. My psoriasis have dotted about a bit since but I know they will all come back again if I stop with the tablets. That's what I want to do but I don't want that old body back, I am a new person now. Since taking hydroxycarbamide I have had a few very bad sore throats also.
Thanks for your help
From this study (7 months ago):
In 2003 after a routine blood test was discovered with the desease.Have had to use both drugs and have only been able to get platelets count below 700, Since then I have developed foot ulcer and excessive sweating.I am also very tired and sometimes feels like I cant go another moment.
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