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Review: could Hydroxyzine cause Restless legs syndrome (Restless leg syndrome)?

Summary: Restless legs syndrome is found among people who take Hydroxyzine, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Hydroxyzine hcl, and have Restless leg syndrome. We study 8,492 people who have side effects while taking Hydroxyzine from FDA and social media. Among them, 30 have Restless legs syndrome. Find out below who they are, when they have Restless legs syndrome and more.

You are not alone: join a support group for people who take Hydroxyzine and have Restless legs syndrome >>>

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Hydroxyzine

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. (latest outcomes from 9,117 Hydroxyzine users)

Restless legs syndrome

Restless legs syndrome (a powerful urge to move your legs) has been reported by people with osteoporosis, depression, pain, high blood pressure, stress and anxiety. (latest reports from 17,510 Restless legs syndrome patients)

On Apr, 30, 2015: 8,489 people reported to have side effects when taking Hydroxyzine. Among them, 30 people (0.35%) have Restless Legs Syndrome.

Trend of Restless legs syndrome in Hydroxyzine reports

Time on Hydroxyzine when people have Restless legs syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Restless legs syndrome50.00%50.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Restless legs syndrome when taking Hydroxyzine * :

FemaleMale
Restless legs syndrome81.48%18.52%

Age of people who have Restless legs syndrome when taking Hydroxyzine * :

0-12-910-1920-2930-3940-4950-5960+
Restless legs syndrome0.00%0.00%0.00%8.33%4.17%16.67%8.33%62.50%

Severity of Restless legs syndrome when taking Hydroxyzine ** :

leastmoderateseveremost severe
Restless legs syndrome0.00%50.00%50.00%0.00%

How people recovered from Restless legs syndrome ** :

while on the drugafter off the drugnot yet
Restless legs syndrome33.33%0.00%66.67%

Top conditions involved for these people * :

  1. Restless legs syndrome (9 people, 30.00%)
  2. General anaesthesia (6 people, 20.00%)
  3. Gastrooesophageal reflux disease (4 people, 13.33%)
  4. Insomnia (3 people, 10.00%)
  5. Anxiety (2 people, 6.67%)

Top co-used drugs for these people * :

  1. Hydroxyzine hcl (11 people, 36.67%)
  2. Propofol (9 people, 30.00%)
  3. Sufentanil (8 people, 26.67%)
  4. Pramipexole (8 people, 26.67%)
  5. Droperidol (8 people, 26.67%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Restless Legs Syndrome while taking Hydroxyzine?

 

You are not alone! Join a support group on :
- support group for people who take Hydroxyzine and have Restless Legs Syndrome
- support group for people who take Hydroxyzine
- support group for people who have Restless Legs Syndrome

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Comments from related studies:

  • From this study (9 months ago):

  • This drug does not help a person with social anxiety and or panic disorder. I was tired for the first couple of days but couldn't sleep due to restless leg. Now, after three weeks of taking it, I'm up til 2am. Does not help me sleep. I feel restless and tired/awake.

    Reply

    Thomas Mofield on Sep, 1, 2014:

    The FDA has approved Ambien (Zolpidem) as an off label treatment for restless leg syndrome. Ambien is a sedative and is used to help you sleep.

    A word of caution: Although zolpidem is used as an off label treatment for restless leg, sometimes it will make little difference, and sometimes it can make it worse (this is rare though). Give it a shot. Hope you get some restful sleep.

    I sometimes get restless leg, the only thing that helps me (oddly enough) is to sleep with my feet uncovered. I don't know why this works, but it does for me.

    Reply

  • From this study (2 years ago):

  • Frustrated with weight gain, fatigue and overall pain. I want to know which is causing weight gain. I also feel horrible most of the time.

    Reply

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