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Review: could Hydroxyzine cause Restless legs syndrome?

We study 8,449 people who have side effects while taking Hydroxyzine from FDA and social media. Among them, 30 have Restless legs syndrome. Find out below who they are, when they have Restless legs syndrome and more.

Stay connected: join a mobile support group for people who take Hydroxyzine and have Restless legs syndrome >>>

Hydroxyzine

Hydroxyzine (latest outcomes from 9,070 users) has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety.

Restless legs syndrome

Restless legs syndrome (a powerful urge to move your legs) (latest reports from 68,696 patients) has been reported by people with restless leg syndrome, osteoporosis, depression, high blood pressure, pain.

On Aug, 18, 2014: 8,448 people reported to have side effects when taking Hydroxyzine. Among them, 30 people (0.36%) have Restless Legs Syndrome. They amount to 0.04% of all the 67,957 people who have Restless Legs Syndrome on eHealthMe.

Trend of Restless legs syndrome in Hydroxyzine reports

Time on Hydroxyzine when people have Restless legs syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Restless legs syndrome50.00%50.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Restless legs syndrome when taking Hydroxyzine * :

FemaleMale
Restless legs syndrome81.48%18.52%

Age of people who have Restless legs syndrome when taking Hydroxyzine * :

0-12-910-1920-2930-3940-4950-5960+
Restless legs syndrome0.00%0.00%0.00%8.33%4.17%16.67%8.33%62.50%

Severity of Restless legs syndrome when taking Hydroxyzine ** :

leastmoderateseveremost severe
Restless legs syndrome0.00%50.00%50.00%0.00%

How people recovered from Restless legs syndrome ** :

while on the drugafter off the drugnot yet
Restless legs syndrome33.33%0.00%66.67%

Top conditions involved for these people * :

  1. Restless legs syndrome (9 people, 30.00%)
  2. General anaesthesia (6 people, 20.00%)
  3. Gastrooesophageal reflux disease (4 people, 13.33%)
  4. Insomnia (3 people, 10.00%)
  5. Anxiety (2 people, 6.67%)

Top co-used drugs for these people * :

  1. Hydroxyzine hcl (11 people, 36.67%)
  2. Propofol (9 people, 30.00%)
  3. Sufentanil (8 people, 26.67%)
  4. Pramipexole (8 people, 26.67%)
  5. Droperidol (8 people, 26.67%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Hydroxyzine and have Restless Legs Syndrome
- group for people who take Hydroxyzine
- group for people who have Restless Legs Syndrome

Comments from related studies:

  • From this study (1 day ago):

  • This drug does not help a person with social anxiety and or panic disorder. I was tired for the first couple of days but couldn't sleep due to restless leg. Now, after three weeks of taking it, I'm up til 2am. Does not help me sleep. I feel restless and tired/awake.

    Reply

    Thomas Mofield on Sep, 1, 2014:

    The FDA has approved Ambien (Zolpidem) as an off label treatment for restless leg syndrome. Ambien is a sedative and is used to help you sleep.

    A word of caution: Although zolpidem is used as an off label treatment for restless leg, sometimes it will make little difference, and sometimes it can make it worse (this is rare though). Give it a shot. Hope you get some restful sleep.

    I sometimes get restless leg, the only thing that helps me (oddly enough) is to sleep with my feet uncovered. I don't know why this works, but it does for me.

    Reply

  • From this study (1 year ago):

  • Frustrated with weight gain, fatigue and overall pain. I want to know which is causing weight gain. I also feel horrible most of the time.

    Reply

  • From this study (1 year ago):

  • I'm miserable with this and I don't even know where to start as the symptom has developed into something incredibly disruptive to my life, especially sleep

    Reply

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On eHealthMe, Hydroxyzine (hydroxyzine hydrochloride) is often used for stress and anxiety. Find out below the conditions Hydroxyzine is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Hydroxyzine used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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