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Review: could Ibuprofen cause Leg swelling (Foot, leg, and ankle swelling)?

Summary: Leg swelling is found among people who take Ibuprofen, especially for people who are female, 30-39 old, also take medication Aspirin, and have Pain.

We study 58,018 people who have side effects while taking Ibuprofen from FDA and social media. Among them, 12 have Leg swelling. Find out below who they are, when they have Leg swelling and more.

You are not alone: join a mobile support group for people who take Ibuprofen and have Leg swelling >>>

 

 

 

 

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from 61,637 Ibuprofen users)

Leg swelling

Leg swelling has been reported by people with high blood pressure, depression, high blood cholesterol, gastroesophageal reflux disease, hypothyroidism. (latest reports from 1,420 Leg swelling patients)

On Feb, 4, 2015: 58,005 people reported to have side effects when taking Ibuprofen. Among them, 12 people (0.02%) have Leg Swelling.

Trend of Leg swelling in Ibuprofen reports

Time on Ibuprofen when people have Leg swelling * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Leg swelling18.18%9.09%0.00%27.27%18.18%0.00%27.27%

Gender of people who have Leg swelling when taking Ibuprofen * :

FemaleMale
Leg swelling75.00%25.00%

Age of people who have Leg swelling when taking Ibuprofen * :

0-12-910-1920-2930-3940-4950-5960+
Leg swelling0.00%8.33%0.00%0.00%25.00%25.00%16.67%25.00%

Severity of Leg swelling when taking Ibuprofen ** :

leastmoderateseveremost severe
Leg swelling8.33%41.67%41.67%8.33%

How people recovered from Leg swelling ** :

while on the drugafter off the drugnot yet
Leg swelling10.00%10.00%80.00%

Top conditions involved for these people * :

  1. Pain (5 people, 41.67%)
  2. Anxiety (2 people, 16.67%)
  3. Inflammation (2 people, 16.67%)
  4. Headache (2 people, 16.67%)
  5. Iron deficiency anaemia (1 people, 8.33%)

Top co-used drugs for these people * :

  1. Aspirin (2 people, 16.67%)
  2. Cetirizine hydrochloride allergy (1 people, 8.33%)
  3. Lisinopril (1 people, 8.33%)
  4. Ferrous fumarate (1 people, 8.33%)
  5. Furosemide (1 people, 8.33%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of ibuprofen and leg swelling on

Do you have Leg Swelling while taking Ibuprofen?

You are not alone! Join a mobile support group:
- support group for people who take Ibuprofen and have Leg Swelling
- support group for people who take Ibuprofen
- support group for people who have Leg Swelling

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • Does toviaz interact negatively with ibuproffen
    Male, 62 years old. Had a prostatectomy months ago (cancerous, 7 rating). One month after surgery, I started taking one 4 mg pill of Toviaz. Worked like magic with no side effects.
    Three weeks ago, I lost control again. The leakage was so bad in frequency that I had to go back to using pads. This lasted for 5 days before things gradually went back to "almost normal".
    The only difference in medication, food and drinks that I had in those 5 days is I used to take 2 ibuprofen pills (200 mg each) in the morning & 2 at night to deal with headache.
    Once I stopped taking the ibuprofen, things improved.
    Could what happened with me be the result of of interaction between Toviaz & Ibuproffen? I called Pfizer and the lady siad she does not have any information on this
  • 8 year old boy has erratic heartbeat. started tamiflu last week. do i need to quit tamiflu? he had a 104.1 temp when we started treatments.
    Shortly after being dosed with Tamiflu this morning, he had a very erratic heartbeat. He is positive for influenza last Thursday and has been on Tamiflu since and Ibuprofen to manage fever (was up to 104.1 last week). Local clinic wants to see him. I don't feel like taking him there will solve anything. Its returned to normal within an hour of dosing with Tamiflu.
  • Can combo of subutex and carfate cause joint pain (1 answer)
    I am taking Carafate and Nexium for the treatment of several stomach ulcers. In addition I am on Subutex for maintenance of opiate dependence. I am having severe joint pain with this combination. Has anyone else had this situation or reaction?
  • I tested positive for methadone, i have never taken this drug (1 answer)
    I tested positive for methadone, I have never taken this drug. My Dr said I had to have taken it because it was there and that a false positive is out of the question. Could my meds cause methadone to show up on a urine drug test
  • I have been on amlodipine for approximately 3 months and have had terrible swelling in my legs and ankles along with pain and itching. should i be taken off this medication?
    I was previously taking Propranolol for blood pressure which didn't bother me at all, but last year I developed a breathing problem and was given Symbicort to help get rid of wheezing. The Symbicort and Propranolol don't mesh well so I was then put on Amlodipine. The swelling, pain and itching occurred right away. I asked the pharmacist about it and also my doctor and they both said a small percentage of people have this problem on this medication. I have tried many times to get my doctor to take me off of this medication but he insists it is best for me, but I disagree. I really don't want to have this problem for the rest of my life and I also won't have any skin left on my legs from the scratching, not to mention the pain that accompanies the swelling which seem to creep up to my knees and thighs and sometimes is so painful I just go to bed to lay down and hopefully the hydroclorithiazide will remove some of this water so that pain will go away. The doctor also doubled my dose of Losartin and Hydroclorithiazide. I'm up about 4-6 times a night going to the bathroom so it also interrupts my sleep. Is anyone else having this problem. I would prefer to go back on the Propranolol and get something other than Symbicort that won't interact with each other. Then I won't have pain and itching all the time. Does anyone have any input on this. I would really appreciate it.

    Thanks. Debbie CB

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  • Ibuprofen and esophageal stricture
    After taking relatively high-doses of ibuprofen for many years, I developed an esophageal pain when swallowing large pills and experienced two unexplained events of esophageal spasm. A barium esophagram showed a stricture near the lower sphincter with a pencil-sized opening. Confirmed benign with a endoscopy and biopsy, it showed no gastric or duodenal ulcers from the ibuprofen, the stricture was expanded and I experience no discomfort now.
    I believe scarring of the esophagus was the result of taking ibuprofen often during the night with only a sip of water and then going back to bed. The ibuprofen dissolved in the water and by lying down immediately, the concentrated solution did not pass into my stomach but stayed in and irritated the lower esophagus for the rest of the night.
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    This is December and the swelling is worse.

More reviews for: Ibuprofen, Leg swelling

Comments from related studies:

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  • OVARIAN CYCTE 10*7 CM RT SIDED
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  • From this study (6 months ago):

  • I'm having oral surgery in a couple of days & dentist gave me xanax to take for the anxiety. I tried one pill Friday night to see how it would affect me & noticed the swelling Saturday

    Reply

  • From this study (1 year ago):

  • This was administered Post abdominal surgery (hysterectomy)
    Result Severe edema from hips to toes
    Legs burn and itch from edema
    Administered 2,400 mg x three days before discontinued.
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