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Review: could Ibuprofen cause Withdrawal syndrome?

Summary: Withdrawal syndrome is found among people who take Ibuprofen, especially for people who are female, 50-59 old, have been taking the drug for < 1 month, also take medication Lyrica, and have Depression.

We study 58,026 people who have side effects while taking Ibuprofen from FDA and social media. Among them, 139 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.

You are not alone: join a support group for people who take Ibuprofen and have Withdrawal syndrome >>>

 

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from 61,653 Ibuprofen users)

Withdrawal syndrome

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, muscle spasticity, back pain. (latest reports from 9,229 Withdrawal syndrome patients)

On Apr, 12, 2015: 58,026 people reported to have side effects when taking Ibuprofen. Among them, 139 people (0.24%) have Withdrawal Syndrome.

Trend of Withdrawal syndrome in Ibuprofen reports

Time on Ibuprofen when people have Withdrawal syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Withdrawal syndrome50.00%50.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Withdrawal syndrome when taking Ibuprofen * :

FemaleMale
Withdrawal syndrome68.55%31.45%

Age of people who have Withdrawal syndrome when taking Ibuprofen * :

0-12-910-1920-2930-3940-4950-5960+
Withdrawal syndrome0.00%0.00%1.82%11.82%19.09%14.55%40.91%11.82%

Severity of Withdrawal syndrome when taking Ibuprofen ** :

leastmoderateseveremost severe
Withdrawal syndrome0.00%100.00%0.00%0.00%

How people recovered from Withdrawal syndrome ** :

while on the drugafter off the drugnot yet
Withdrawal syndrome0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Depression (41 people, 29.50%)
  2. Pain (28 people, 20.14%)
  3. Bone pain (24 people, 17.27%)
  4. Diabetes mellitus (21 people, 15.11%)
  5. Hypertension (21 people, 15.11%)

Top co-used drugs for these people * :

  1. Lyrica (37 people, 26.62%)
  2. Vicodin (31 people, 22.30%)
  3. Xanax (31 people, 22.30%)
  4. Neurontin (29 people, 20.86%)
  5. Temazepam (27 people, 19.42%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

Comments for this study:

motoboy (3 months ago):

I've recently stopped taking ibuprofen after many years of taking it daily. I take between 800 to 1500 mg a day, mostly before bed to sleep. I have had a lot of sport injuries do it was for joint pain. It's been about a week since taking any and I'm getting really bad headaches. Can't seem to find this as a withdrawal issue... any one else experience this? Thanks!
Reply the comment

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of ibuprofen and withdrawal syndrome on

Do you have Withdrawal Syndrome while taking Ibuprofen?

 

 

 

You are not alone! Join a support group on :
- support group for people who take Ibuprofen and have Withdrawal Syndrome
- support group for people who take Ibuprofen
- support group for people who have Withdrawal Syndrome

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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