Review: could Isoniazid cause Headache?


Headache is found among people who take Isoniazid, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Pyrazinamide, and have Rheumatoid arthritis . We study 8,107 people who have side effects while taking Isoniazid from FDA and social media. Among them, 211 have Headache. Find out below who they are, when they have Headache and more.

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Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. (latest outcomes from Isoniazid 8,225 users)


Headache (pain in head) has been reported by people with breathing difficulty, pain, drug ineffective, chest pain, fatigue (latest reports from 191,732 Headache patients).

On Aug, 21, 2016

8,107 people reported to have side effects when taking Isoniazid.
Among them, 211 people (2.6%) have Headache

Number of reports submitted per year:

Could Isoniazid cause Headache?

Time on Isoniazid when people have Headache *:

  • < 1 month: 43.9 %
  • 1 - 6 months: 39.02 %
  • 6 - 12 months: 9.76 %
  • 1 - 2 years: 2.44 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 4.88 %
  • 10+ years: 0.0 %

Gender of people who have Headache when taking Isoniazid *:

  • female: 64.11 %
  • male: 35.89 %

Age of people who have Headache when taking Isoniazid *:

  • 0-1: 0.0 %
  • 2-9: 1.65 %
  • 10-19: 3.3 %
  • 20-29: 15.38 %
  • 30-39: 18.68 %
  • 40-49: 20.33 %
  • 50-59: 18.13 %
  • 60+: 22.53 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (64 people)
  • Tuberculosis (36 people)
  • Hiv Infection (22 people)
  • Prophylaxis (13 people)
  • Ankylosing Spondylitis (10 people)

Top co-used drugs for these people *:

  • Pyrazinamide (44 people)
  • Rifampicin (42 people)
  • Methotrexate (42 people)
  • Prednisolone (36 people)
  • Remicade (30 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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