Review: could Isoniazid cause Hepatotoxicity?
Summary: Hepatotoxicity is found among people who take Isoniazid, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Rifampicin, and have Tuberculosis.
We study 7,418 people who have side effects while taking Isoniazid from FDA and social media. Among them, 120 have Hepatotoxicity. Find out below who they are, when they have Hepatotoxicity and more.
You are not alone: join a mobile support group for people who take Isoniazid and have Hepatotoxicity >>>
Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. (latest outcomes from 7,571 Isoniazid users)
Hepatotoxicity (chemical-driven liver damage) has been reported by people with hiv infection, pain, depression, high blood pressure, rheumatoid arthritis. (latest reports from 7,111 Hepatotoxicity patients)
On Jan, 1, 2015: 7,417 people reported to have side effects when taking Isoniazid. Among them, 120 people (1.62%) have Hepatotoxicity.
Time on Isoniazid when people have Hepatotoxicity * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Gender of people who have Hepatotoxicity when taking Isoniazid * :
Age of people who have Hepatotoxicity when taking Isoniazid * :
Severity of Hepatotoxicity when taking Isoniazid ** :
How people recovered from Hepatotoxicity ** :
Top conditions involved for these people * :
- Tuberculosis (43 people, 35.83%)
- Hiv infection (31 people, 25.83%)
- Prophylaxis (15 people, 12.50%)
- Pulmonary tuberculosis (10 people, 8.33%)
- Renal transplant (6 people, 5.00%)
Top co-used drugs for these people * :
- Rifampicin (56 people, 46.67%)
- Pyrazinamide (55 people, 45.83%)
- Ethambutol hydrochloride (33 people, 27.50%)
- Rifampin (24 people, 20.00%)
- Cotrim (16 people, 13.33%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Hepatotoxicity while taking Isoniazid?
You are not alone! Join a mobile support group:
- support group for people who take Isoniazid and have Hepatotoxicity
- support group for people who take Isoniazid
- support group for people who have Hepatotoxicity
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More questions for: Isoniazid, Hepatotoxicity
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- Isoniazid: the downside continued
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- Isoniazid--the downside
Started taking Isonizaid approximately June 10. I am having fairly severe memory loss. I am having mental confusion. I am having depression. I have weight gain. I have liver pain, but it has lessened in the last month though it was severe in the first 3 months. I have digestive issues such as heartburn and constipation since I started it. I have very slow healing taking me nearly twice as long to heal. There's something else, but I can't remember it right now.
More reviews for: Isoniazid, Hepatotoxicity
Comments from related studies:
From this study (1 day ago):
Ultrasound showed dilation of bile duct all liver functions elevated!!
From this study (8 months ago):
Got ulcerative colitis after taking isoniazid
From this study (9 months ago):
I have been taking Isoniazid for 6 months now and I have 3 more months to go. After a month 1 1/2 of taking this medication I began to have alot of palpitations and then to PVCs. I have been diagnosed with Paroxysmal A-Fib since 2000 but it is Sinus. I recently stopped the Flecainide because I thought that was causing me to have this problem. But I have been taking Flecainide since 2003.
I don't have Tuberculosis. I will always be positive with TB test because of BCG Vaccine that they did in Asia.
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