eHealthMe - Personalized health information & community eHealthMe - Personalized health information & community

Personalized health information & community

  Tools   Community
All drugs: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
All conditions: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Check symptoms       Compare drugs       Ask question       Write review       Answered/ Unanswered       Reviews

Review: could Isoniazid cause Hepatotoxicity?

Summary: Hepatotoxicity is found among people who take Isoniazid, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Rifampicin, and have Tuberculosis.

We study 7,418 people who have side effects while taking Isoniazid from FDA and social media. Among them, 120 have Hepatotoxicity. Find out below who they are, when they have Hepatotoxicity and more.

You are not alone: join a mobile support group for people who take Isoniazid and have Hepatotoxicity >>>






Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. (latest outcomes from 7,571 Isoniazid users)


Hepatotoxicity (chemical-driven liver damage) has been reported by people with hiv infection, pain, depression, high blood pressure, rheumatoid arthritis. (latest reports from 7,111 Hepatotoxicity patients)

On Mar, 4, 2015: 7,418 people reported to have side effects when taking Isoniazid. Among them, 120 people (1.62%) have Hepatotoxicity.

Trend of Hepatotoxicity in Isoniazid reports

Time on Isoniazid when people have Hepatotoxicity * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Gender of people who have Hepatotoxicity when taking Isoniazid * :


Age of people who have Hepatotoxicity when taking Isoniazid * :


Severity of Hepatotoxicity when taking Isoniazid ** :


How people recovered from Hepatotoxicity ** :


Top conditions involved for these people * :

  1. Tuberculosis (43 people, 35.83%)
  2. Hiv infection (31 people, 25.83%)
  3. Prophylaxis (15 people, 12.50%)
  4. Pulmonary tuberculosis (10 people, 8.33%)
  5. Renal transplant (6 people, 5.00%)

Top co-used drugs for these people * :

  1. Rifampicin (56 people, 46.67%)
  2. Pyrazinamide (55 people, 45.83%)
  3. Ethambutol hydrochloride (33 people, 27.50%)
  4. Rifampin (24 people, 20.00%)
  5. Cotrim (16 people, 13.33%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Hepatotoxicity while taking Isoniazid?

You are not alone! Join a mobile support group:
- support group for people who take Isoniazid and have Hepatotoxicity
- support group for people who take Isoniazid
- support group for people who have Hepatotoxicity

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

More questions for: Isoniazid, Hepatotoxicity

You may be interested at these reviews (Write a review):

  • Isoniazid and deafness
    As a young girl I was put on Isoniazid, I didn't put 2 and 2 together but after taking the inh I started loosing my hearing to the point I'm completely deaf in my left ear. I have found a few people having report that they lost their hearing also. I'm just curious as to about how many people have had this problem.
  • Isoniazid: the downside continued
    I also have extreme fatigue. I can sleep 8 hours and then take a 4 hour nap. I have dizziness which seems to be increasing in the last few weeks. I have nausea on and off. I have diarrhea in the morning 45 minutes after taking it. Then I am mostly constipated for the rest of the day. It seems like my hair is thinning. My skin is drying out or becoming considerably less elastic.
  • Isoniazid--the downside
    Started taking Isonizaid approximately June 10. I am having fairly severe memory loss. I am having mental confusion. I am having depression. I have weight gain. I have liver pain, but it has lessened in the last month though it was severe in the first 3 months. I have digestive issues such as heartburn and constipation since I started it. I have very slow healing taking me nearly twice as long to heal. There's something else, but I can't remember it right now.

More reviews for: Isoniazid, Hepatotoxicity

Comments from related studies:

  • From this study (1 month ago):

  • Ultrasound showed dilation of bile duct all liver functions elevated!!


  • From this study (9 months ago):

  • Got ulcerative colitis after taking isoniazid


  • From this study (10 months ago):

  • I have been taking Isoniazid for 6 months now and I have 3 more months to go. After a month 1 1/2 of taking this medication I began to have alot of palpitations and then to PVCs. I have been diagnosed with Paroxysmal A-Fib since 2000 but it is Sinus. I recently stopped the Flecainide because I thought that was causing me to have this problem. But I have been taking Flecainide since 2003.

    I don't have Tuberculosis. I will always be positive with TB test because of BCG Vaccine that they did in Asia.


Post a new comment    OR    Read more comments

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


About - Terms of service - Privacy policy - Press - Testimonials - Contact us

© 2015 All rights reserved. Use of this site constitutes acceptance of's terms of service and privacy policy.