Isoniazid and Hepatotoxicity - from FDA reports


Summary

Hepatotoxicity is found among people who take Isoniazid, especially for people who are male, 60+ old , have been taking the drug for 1 - 6 months, also take medication Pyrazinamide, and have Tuberculosis. This review analyzes which people have Hepatotoxicity with Isoniazid. It is created by eHealthMe based on reports of 10,469 people who have side effects when taking Isoniazid from FDA, and is updated regularly.

What to expect?

If you take Isoniazid and have Hepatotoxicity, find out what symptoms you could have in 1 year or longer.

You are not alone!

Join a support group for people who take Isoniazid and have Hepatotoxicity

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA since 1977. Our tools are simple to use, anonymous and free. Start now >>>

On Apr, 18, 2017

10,469 people reported to have side effects when taking Isoniazid.
Among them, 225 people (2.15%) have Hepatotoxicity


Number of reports submitted per year:

Could Isoniazid cause Hepatotoxicity?

Time on Isoniazid when people have Hepatotoxicity *:

  • < 1 month: 17.95 %
  • 1 - 6 months: 74.36 %
  • 6 - 12 months: 5.13 %
  • 1 - 2 years: 2.56 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Hepatotoxicity when taking Isoniazid *:

  • female: 48.83 %
  • male: 51.17 %

Age of people who have Hepatotoxicity when taking Isoniazid *:

  • 0-1: 3.47 %
  • 2-9: 4.46 %
  • 10-19: 5.45 %
  • 20-29: 10.4 %
  • 30-39: 14.85 %
  • 40-49: 10.89 %
  • 50-59: 18.32 %
  • 60+: 32.18 %

Top conditions involved for these people *:

  • Tuberculosis (119 people, 52.89%)
  • Hiv Infection (35 people, 15.56%)
  • Pulmonary Tuberculosis (18 people, 8.00%)
  • Preventive Health Care (15 people, 6.67%)
  • Latent Tuberculosis (10 people, 4.44%)

Top co-used drugs for these people *:

  • Pyrazinamide (59 people, 26.22%)
  • Ethambutol Hydrochloride (31 people, 13.78%)
  • Rifampin (24 people, 10.67%)
  • Lamivudine (17 people, 7.56%)
  • Cotrim (16 people, 7.11%)

Top other side effects for these people *:

  • Jaundice - Yellow Skin (63 people, 28.00%)
  • Hepatic Failure (54 people, 24.00%)
  • Liver Function Test Abnormal (49 people, 21.78%)
  • Nausea And Vomiting (19 people, 8.44%)
  • Aspartate Aminotransferase Increased (18 people, 8.00%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Hepatotoxicity when taking Isoniazid?

Isoniazid

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. (latest outcomes from Isoniazid 10,770 users)

Hepatotoxicity

Hepatotoxicity (chemical-driven liver damage) has been reported by people with hiv infection, pain, high blood pressure, rheumatoid arthritis, preventive health care (latest reports from 8,678 Hepatotoxicity patients).

Browse all side effects of Isoniazid

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Hepatotoxicity

Hepatotoxicity

Could your condition cause Hepatotoxicity

Hepatotoxicity

Related studies

What would happen?

Forecast new side effects and undetected conditions when you take Isoniazid and have Hepatotoxicity.

Can you answer these questions?

More questions for: Isoniazid, Hepatotoxicity

You may be interested in these reviews

More reviews for: Isoniazid, Hepatotoxicity