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Review: could Isoniazid cause Mental disorder?

Summary: Mental disorder is found among people who take Isoniazid, especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months, also take medication Pyrazinamide, and have Hiv infection.

We study 7,418 people who have side effects while taking Isoniazid from FDA and social media. Among them, 24 have Mental disorder. Find out below who they are, when they have Mental disorder and more.

You are not alone: join a mobile support group for people who take Isoniazid and have Mental disorder >>>






Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. (latest outcomes from 7,571 Isoniazid users)

Mental disorder

Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability) has been reported by people with quit smoking, depression, birth control, pain, stress and anxiety. (latest reports from 20,983 Mental disorder patients)

On Jan, 28, 2015: 7,418 people reported to have side effects when taking Isoniazid. Among them, 24 people (0.32%) have Mental Disorder.

Trend of Mental disorder in Isoniazid reports

Time on Isoniazid when people have Mental disorder * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Mental disorder14.29%57.14%0.00%0.00%28.57%0.00%0.00%

Gender of people who have Mental disorder when taking Isoniazid * :

Mental disorder73.91%26.09%

Age of people who have Mental disorder when taking Isoniazid * :

Mental disorder0.00%9.52%0.00%0.00%57.14%14.29%19.05%0.00%

Severity of Mental disorder when taking Isoniazid ** :


How people recovered from Mental disorder ** :


Top conditions involved for these people * :

  1. Hiv infection (16 people, 66.67%)
  2. Pulmonary tuberculosis (4 people, 16.67%)
  3. Tuberculosis (4 people, 16.67%)
  4. Prophylaxis (4 people, 16.67%)
  5. Hypertension (2 people, 8.33%)

Top co-used drugs for these people * :

  1. Pyrazinamide (17 people, 70.83%)
  2. Rifampicin (15 people, 62.50%)
  3. Lamivudine (11 people, 45.83%)
  4. Zidovudine (10 people, 41.67%)
  5. Nevirapine (9 people, 37.50%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Mental Disorder while taking Isoniazid?

You are not alone! Join a mobile support group:
- support group for people who take Isoniazid and have Mental Disorder
- support group for people who take Isoniazid
- support group for people who have Mental Disorder

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  • Isoniazid and deafness
    As a young girl I was put on Isoniazid, I didn't put 2 and 2 together but after taking the inh I started loosing my hearing to the point I'm completely deaf in my left ear. I have found a few people having report that they lost their hearing also. I'm just curious as to about how many people have had this problem.
  • Isoniazid: the downside continued
    I also have extreme fatigue. I can sleep 8 hours and then take a 4 hour nap. I have dizziness which seems to be increasing in the last few weeks. I have nausea on and off. I have diarrhea in the morning 45 minutes after taking it. Then I am mostly constipated for the rest of the day. It seems like my hair is thinning. My skin is drying out or becoming considerably less elastic.
  • Isoniazid--the downside
    Started taking Isonizaid approximately June 10. I am having fairly severe memory loss. I am having mental confusion. I am having depression. I have weight gain. I have liver pain, but it has lessened in the last month though it was severe in the first 3 months. I have digestive issues such as heartburn and constipation since I started it. I have very slow healing taking me nearly twice as long to heal. There's something else, but I can't remember it right now.

More reviews for: Isoniazid, Mental disorder

Comments from related studies:

  • From this study (3 weeks ago):

  • Ultrasound showed dilation of bile duct all liver functions elevated!!


  • From this study (8 months ago):

  • Got ulcerative colitis after taking isoniazid


  • From this study (10 months ago):

  • I have been taking Isoniazid for 6 months now and I have 3 more months to go. After a month 1 1/2 of taking this medication I began to have alot of palpitations and then to PVCs. I have been diagnosed with Paroxysmal A-Fib since 2000 but it is Sinus. I recently stopped the Flecainide because I thought that was causing me to have this problem. But I have been taking Flecainide since 2003.

    I don't have Tuberculosis. I will always be positive with TB test because of BCG Vaccine that they did in Asia.


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