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Review: could Janumet cause Headaches (Headache)?

Summary: Headaches is found among people who take Janumet, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Glyburide, and have Diabetes.

We study 3,184 people who have side effects while taking Janumet from FDA and social media. Among them, 86 have Headaches. Find out below who they are, when they have Headaches and more.

You are not alone: join a mobile support group for people who take Janumet and have Headaches >>>






Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. (latest outcomes from 3,394 Janumet users)


Headaches (pain in head) has been reported by people with multiple sclerosis, depression, high blood pressure, rheumatoid arthritis, osteoporosis. (latest reports from 168,758 Headaches patients)

On Jan, 23, 2015: 3,182 people reported to have side effects when taking Janumet. Among them, 86 people (2.70%) have Headaches.

Trend of Headaches in Janumet reports

Time on Janumet when people have Headaches * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Gender of people who have Headaches when taking Janumet * :


Age of people who have Headaches when taking Janumet * :


Severity of Headaches when taking Janumet ** :

leastmoderateseveremost severe

How people recovered from Headaches ** :

while on the drugafter off the drugnot yet

Top conditions involved for these people * :

  1. Diabetes mellitus (30 people, 34.88%)
  2. Type 2 diabetes mellitus (25 people, 29.07%)
  3. Hypertension (16 people, 18.60%)
  4. Blood cholesterol increased (11 people, 12.79%)
  5. Atrial fibrillation (6 people, 6.98%)

Top co-used drugs for these people * :

  1. Glyburide (15 people, 17.44%)
  2. Nexium (13 people, 15.12%)
  3. Aspirin (12 people, 13.95%)
  4. Metformin (12 people, 13.95%)
  5. Ramipril (11 people, 12.79%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Headaches while taking Janumet?

You are not alone! Join a mobile support group:
- support group for people who take Janumet and have Headaches
- support group for people who take Janumet

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More questions for: Janumet, Headaches

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More reviews for: Janumet, Headaches

Comments from related studies:

  • From this study (2 years ago):

  • Strokes symptoms came and went in a week's time, but never were treated or really diagnosed with anything but pacymeningitis a year ago. Still insomnia, headaches, shoulder and neck pain persist. Wondering if sleep medicine and other medicine intereactions from diabetes. could be a cause. Still looking for treatment


    beccadoggie on Nov, 28, 2012:

    Are your sleep problems caused by your mattress? Many mattresses since 2000 are made with synthetic chemicals. Example: Memory foam comes from polyurethane which is made from extremely toxic 2,4-Toluene diisocyanate. It was also stuffed in my upper level leather recliner and I coughed a dry hacking cough all night, every night.

    A new mattress from organic materials, latex from trees, wool from sheep wrapped around some of the latex layers, and the whole encased in certified organic cotton is heavenly. You'll be sleeping on a cloud. Check out Organic Mattress Inc. or SavvyRest.

    I rarely use sleeping aids, but if I do, I use Valerian root according to the label on the bottle (buy at health food stores). Instead, I make certain I eat enough calcium rich foods and always add vitamin D3 with my fattiest meals.

    Kale, bok choy, collard greens, broccoli, figs, certified organic tofu (MoriNu), and organic yogurt like Stonyfield Farms can help your body get the calcium it needs for a restful sleep, not to mention to build bones.


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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