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Review: could Keppra cause Depression?

Summary: Depression could be caused by Keppra, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Lamictal, and have Convulsion.

We study 19,626 people who have side effects while taking Keppra from FDA and social media. Among them, 613 have Depression. Find out below who they are, when they have Depression and more.

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Keppra

Keppra (latest outcomes from 21,127 users) has active ingredients of levetiracetam. It is often used in epilepsy, seizures. Commonly reported side effects of Keppra include convulsion, convulsion prophylaxis, fatigue, fatigue aggravated, weakness.

Depression

Depression (latest reports from 1,144,595 patients) has been reported by people with quit smoking, multiple sclerosis, pain, pain relief by acupuncture, acupuncture and pain.

On Apr, 16, 2014: 19,626 people reported to have side effects when taking Keppra. Among them, 665 people (3.39%) have Depression. They amount to 0.06% of all the 1,146,681 people who have Depression on eHealthMe.

Trend of Depression in Keppra reports

Time on Keppra when people have Depression * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Depression44.32%35.23%7.39%3.98%6.25%1.70%1.14%

Gender of people who have Depression when taking Keppra * :

FemaleMale
Depression61.85%38.15%

Age of people who have Depression when taking Keppra * :

0-12-910-1920-2930-3940-4950-5960+
Depression0.26%1.31%8.10%9.54%19.87%18.56%21.18%21.18%

Severity of Depression when taking Keppra ** :

leastmoderateseveremost severe
Depression18.18%45.45%27.27%9.09%

How people recovered from Depression ** :

while on the drugafter off the drugnot yet
Depression0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Convulsion (218 people, 32.78%)
  2. Epilepsy (214 people, 32.18%)
  3. Pain (52 people, 7.82%)
  4. Multiple sclerosis (49 people, 7.37%)
  5. Depression (43 people, 6.47%)

Top co-used drugs for these people * :

  1. Lamictal (143 people, 21.50%)
  2. Neurontin (108 people, 16.24%)
  3. Tegretol (94 people, 14.14%)
  4. Dilantin (81 people, 12.18%)
  5. Topamax (81 people, 12.18%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Keppra, Depression

You can also:

On eHealthMe, Keppra (levetiracetam) is often used for epilepsy. Find out below the conditions Keppra is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Keppra used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (1 year ago):

  • I've always had the Simian Crease and Epilepsy. Do they correlate to a specific diagnosis?

    Reply

  • From this study (1 year ago):

  • I was on Keppra since age 15 and I.took my self off of it (Keppra) 1) because I couldn't afford it and 2) because I was tired of the zombie like feeling . I haven't had a seizure. I exercise a lot eat healthy. My concern ha that I have suddenly been off of it for about two years now but I feel.that the agitation has worsen over the years and my headaches are worsening and more constant since being.off of it. Are there anystudies done bout what happens after one has gone off Leopard. I was taking 2000 mg a day

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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