Review: could Keppra cause Withdrawal Syndrome?


Summary

Withdrawal syndrome is found among people who take Keppra, especially for people who are male, 50-59 old , have been taking the drug for 1 - 6 months, also take medication Seroquel, and have Epilepsy . We study 33,173 people who have side effects while taking Keppra from FDA and social media. Among them, 46 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.

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Keppra

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. (latest outcomes from Keppra 36,049 users)

Withdrawal Syndrome

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with irritability, drug withdrawal syndrome, agitation, insomnia, fatigue (latest reports from 13,189 Withdrawal syndrome patients).

On Sep, 15, 2016

33,173 people reported to have side effects when taking Keppra.
Among them, 46 people (0.14%) have Withdrawal Syndrome


Number of reports submitted per year:

Could Keppra cause Withdrawal syndrome?

Time on Keppra when people have Withdrawal Syndrome *:

  • < 1 month: 15.38 %
  • 1 - 6 months: 46.15 %
  • 6 - 12 months: 38.46 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Withdrawal Syndrome when taking Keppra *:

  • female: 40 %
  • male: 60 %

Age of people who have Withdrawal Syndrome when taking Keppra *:

  • 0-1: 15.62 %
  • 2-9: 3.12 %
  • 10-19: 3.12 %
  • 20-29: 21.88 %
  • 30-39: 3.12 %
  • 40-49: 21.88 %
  • 50-59: 28.12 %
  • 60+: 3.12 %

Top conditions involved for these people *:

  • Epilepsy (15 people, 32.61%)
  • Depression (6 people, 13.04%)
  • Hypothyroidism (5 people, 10.87%)
  • Convulsion (4 people, 8.70%)
  • Borderline Personality Disorder (4 people, 8.70%)

Top co-used drugs for these people *:

  • Seroquel (8 people, 17.39%)
  • Tegretol (7 people, 15.22%)
  • Rivotril (7 people, 15.22%)
  • Heroin (7 people, 15.22%)
  • Euthyrox (7 people, 15.22%)

Top other side effects for these people *:

  • Drug Ineffective (13 people, 28.26%)
  • Convulsion (12 people, 26.09%)
  • Anxiety (10 people, 21.74%)
  • Pyrexia (7 people, 15.22%)
  • Muscle Spasms (7 people, 15.22%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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