Review: could Lamictal cause Depression?


Summary

Depression is found among people who take Lamictal, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Seroquel, and have Bipolar disorder . We study 38,205 people who have side effects while taking Lamictal from FDA and social media. Among them, 1,455 have Depression. Find out below who they are, when they have Depression and more.

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Lamictal

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. (latest outcomes from Lamictal 40,259 users)

Depression

Depression has been reported by people with suicidal ideation, drug ineffective, drug exposure during pregnancy, insomnia, fatigue (latest reports from 245,188 Depression patients).

On Jul, 21, 2016

38,205 people reported to have side effects when taking Lamictal.
Among them, 1,455 people (3.81%) have Depression


Number of reports submitted per year:

Could Lamictal cause Depression?

Time on Lamictal when people have Depression *:

  • < 1 month: 29.11 %
  • 1 - 6 months: 25.74 %
  • 6 - 12 months: 8.02 %
  • 1 - 2 years: 10.13 %
  • 2 - 5 years: 14.35 %
  • 5 - 10 years: 9.7 %
  • 10+ years: 2.95 %

Gender of people who have Depression when taking Lamictal *:

  • female: 74.96 %
  • male: 25.04 %

Age of people who have Depression when taking Lamictal *:

  • 0-1: 0.0 %
  • 2-9: 0.17 %
  • 10-19: 8.37 %
  • 20-29: 15.13 %
  • 30-39: 15.47 %
  • 40-49: 22.82 %
  • 50-59: 24.85 %
  • 60+: 13.19 %

Severity if Depression when taking Lamictal **:

  • least: 2.99 %
  • moderate: 37.31 %
  • severe: 37.31 %
  • most severe: 22.39 %

How people recovered from Depression **:

  • while on drug: 2.63 %
  • after off the drug: 31.58 %
  • not yet: 65.79 %

Top conditions involved for these people *:

  • Bipolar Disorder (383 people)
  • Depression (337 people)
  • Anxiety (117 people)
  • Smoking Cessation Therapy (104 people)
  • Epilepsy (98 people)

Top co-used drugs for these people *:

  • Seroquel (217 people)
  • Klonopin (161 people)
  • Cymbalta (155 people)
  • Lexapro (133 people)
  • Neurontin (127 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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