Could Lamictal cause Depression - from FDA reports


Summary

Depression is found among people who take Lamictal, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Seroquel, and have Bipolar disorder . We study 50,143 people who have side effects while taking Lamictal from FDA. Among them, 1,921 have Depression. Find out below who they are, when they have Depression and more.

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Lamictal

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. (latest outcomes from Lamictal 54,727 users)

Depression

Depression has been reported by people with depression, multiple sclerosis, quit smoking, pain (latest reports from 364,690 Depression patients).

On Nov, 22, 2016

50,143 people reported to have side effects when taking Lamictal.
Among them, 1,921 people (3.83%) have Depression


Number of reports submitted per year:

Could Lamictal cause Depression?

Time on Lamictal when people have Depression *:

  • < 1 month: 28.99 %
  • 1 - 6 months: 25.72 %
  • 6 - 12 months: 7.25 %
  • 1 - 2 years: 10.51 %
  • 2 - 5 years: 14.49 %
  • 5 - 10 years: 9.78 %
  • 10+ years: 3.26 %

Gender of people who have Depression when taking Lamictal *:

  • female: 74.56 %
  • male: 25.44 %

Age of people who have Depression when taking Lamictal *:

  • 0-1: 0.0 %
  • 2-9: 0.14 %
  • 10-19: 8.07 %
  • 20-29: 13.08 %
  • 30-39: 16.01 %
  • 40-49: 23.03 %
  • 50-59: 24.22 %
  • 60+: 15.45 %

Severity of Depression **:

  • least: 3.17 %
  • moderate: 38.1 %
  • severe: 38.1 %
  • most severe: 20.63 %

Top conditions involved for these people *:

  • Bipolar Disorder (503 people, 26.18%)
  • Stress And Anxiety (163 people, 8.49%)
  • Epilepsy (148 people, 7.70%)
  • Pain (113 people, 5.88%)
  • Quit Smoking (110 people, 5.73%)

Top co-used drugs for these people *:

  • Seroquel (313 people, 16.29%)
  • Klonopin (215 people, 11.19%)
  • Cymbalta (211 people, 10.98%)
  • Abilify (185 people, 9.63%)
  • Lexapro (176 people, 9.16%)

Top other side effects for these people *:

  • Stress And Anxiety (534 people, 27.80%)
  • Suicidal Ideation (341 people, 17.75%)
  • Fatigue (308 people, 16.03%)
  • Insomnia (259 people, 13.48%)
  • Drug Ineffective (256 people, 13.33%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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