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Review: could Lamotrigine cause Renal failure?

Summary: Renal failure could be caused by Lamotrigine, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take Phenytoin, and have Epilepsy.

We study 14,660 people who have side effects while taking Lamotrigine from FDA and social media. Among them, 118 have Renal failure. Find out below who they are, when they have Renal failure and more.

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On Apr, 12, 2014: 14,599 people reported to have side effects when taking Lamotrigine. Among them, 128 people (0.88%) have Renal Failure. They amount to 0.03% of all the 430,639 people who have Renal Failure on eHealthMe.

Trend of Renal failure in Lamotrigine reports

Time on Lamotrigine when people have Renal failure * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Renal failure75.00%12.50%12.50%0.00%0.00%0.00%0.00%

Gender of people who have Renal failure when taking Lamotrigine * :

FemaleMale
Renal failure42.96%57.04%

Age of people who have Renal failure when taking Lamotrigine * :

0-12-910-1920-2930-3940-4950-5960+
Renal failure0.00%0.00%21.01%6.72%3.36%28.57%6.72%33.61%

Severity of Renal failure when taking Lamotrigine ** :

n/a

How people recovered from Renal failure ** :

n/a

Top conditions involved for these people * :

  1. Epilepsy (35 people, 27.34%)
  2. Bipolar disorder (17 people, 13.28%)
  3. Convulsion (16 people, 12.50%)
  4. Grand mal convulsion (10 people, 7.81%)
  5. Peritoneal dialysis (8 people, 6.25%)

Top co-used drugs for these people * :

  1. Phenytoin (26 people, 20.31%)
  2. Valproate sodium (21 people, 16.41%)
  3. Topiramate (18 people, 14.06%)
  4. Valproic acid (18 people, 14.06%)
  5. Zofran (15 people, 11.72%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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Related topic: Lamotrigine, Renal failure

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On eHealthMe, Lamotrigine (lamotrigine) is often used for bipolar disorder. Find out below the conditions Lamotrigine is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Lamotrigine used for and how effective is it:

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Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (7 hours ago):

  • Should I take electrolyte supplements?

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  • From this study (2 days ago):

  • was taken off the efexor XR, trazedone, and sertraline when diagnosed with serotonin toxity

    Reply

  • From this study (2 days ago):

  • Before this medication I was taking 300mg of Effexor, 300mg of trazedone, 15 mg of diazepam, and 100mg of Zoloft. Was diagnosed with serotonin toxicity and removed from all but the diazepam and given 5mg of Sonata, starting dose of 25mg of lamotrigine (upped 2x- 1st to 50mg and then to 100mg) and 20 mg of diazepam.

    Reply

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