Lamotrigine and Renal failure - from FDA reports


Summary

Renal failure is found among people who take Lamotrigine, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Phenytoin, and have Convulsion. This review analyzes which people have Renal failure with Lamotrigine. It is created by eHealthMe based on reports of 28,464 people who have side effects when taking Lamotrigine from FDA , and is updated regularly.

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On Sep, 24, 2017

28,464 people reported to have side effects when taking Lamotrigine.
Among them, 198 people (0.7%) have Renal failure


Number of reports submitted per year:

Could Lamotrigine cause Renal failure?

Time on Lamotrigine when people have Renal failure *:

  • < 1 month: 85.71 %
  • 1 - 6 months: 9.52 %
  • 6 - 12 months: 4.76 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Renal failure when taking Lamotrigine *:

  • female: 43.52 %
  • male: 56.48 %

Age of people who have Renal failure when taking Lamotrigine *:

  • 0-1: 0.0 %
  • 2-9: 1.2 %
  • 10-19: 17.47 %
  • 20-29: 5.42 %
  • 30-39: 8.43 %
  • 40-49: 20.48 %
  • 50-59: 14.46 %
  • 60+: 32.53 %

Top conditions involved for these people *:

  • Depression (16 people, 8.08%)
  • Convulsion (16 people, 8.08%)
  • High Blood Pressure (11 people, 5.56%)
  • Pain (10 people, 5.05%)
  • Stress And Anxiety (9 people, 4.55%)

Top co-used drugs for these people *:

  • Phenytoin (29 people, 14.65%)
  • Valproate Sodium (21 people, 10.61%)
  • Valproic Acid (18 people, 9.09%)
  • Topiramate (18 people, 9.09%)
  • Zofran (12 people, 6.06%)

Top other side effects for these people *:

  • Hypotension (39 people, 19.70%)
  • Disseminated Intravascular Coagulation (34 people, 17.17%)
  • Multi-Organ Failure (30 people, 15.15%)
  • Rhabdomyolysis (28 people, 14.14%)
  • Sepsis (27 people, 13.64%)

* Approximation only. Some reports may have incomplete information.

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Renal failure and Lamotrigine from FDA and eHealthMe reports

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