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Review: could Letrozole cause Osteoporosis?

Summary: Osteoporosis is found among people who take Letrozole, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years, also take medication Zometa, and have Breast cancer.

We study 1,765 people who have side effects while taking Letrozole from FDA and social media. Among them, 25 have Osteoporosis. Find out below who they are, when they have Osteoporosis and more.

You are not alone: join a mobile support group for people who take Letrozole and have Osteoporosis >>>

 

 

 

 

Letrozole

Letrozole has active ingredients of letrozole. It is often used in breast cancer. (latest outcomes from 1,841 Letrozole users)

Osteoporosis

Osteoporosis (bones weak and more likely to break) has been reported by people with osteopenia, high blood pressure, rheumatoid arthritis, pain, high blood cholesterol. (latest reports from 112,578 Osteoporosis patients)

On Dec, 31, 2014: 1,761 people reported to have side effects when taking Letrozole. Among them, 25 people (1.42%) have Osteoporosis.

Trend of Osteoporosis in Letrozole reports

Time on Letrozole when people have Osteoporosis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Osteoporosis0.00%25.00%25.00%25.00%0.00%25.00%0.00%

Age of people who have Osteoporosis when taking Letrozole * :

0-12-910-1920-2930-3940-4950-5960+
Osteoporosis0.00%0.00%0.00%0.00%0.00%20.69%34.48%44.83%

Severity of Osteoporosis when taking Letrozole ** :

leastmoderateseveremost severe
Osteoporosis50.00%50.00%0.00%0.00%

How people recovered from Osteoporosis ** :

n/a

Top conditions involved for these people * :

  1. Breast cancer (25 people, 100.00%)
  2. Anaemia (18 people, 72.00%)
  3. Hypertension (1 people, 4.00%)
  4. Hyperlipidaemia (1 people, 4.00%)
  5. Anxiety (1 people, 4.00%)

Top co-used drugs for these people * :

  1. Zometa (25 people, 100.00%)
  2. Morphine (24 people, 96.00%)
  3. Chemotherapeutics nos (24 people, 96.00%)
  4. Aloxi (24 people, 96.00%)
  5. Navelbine (24 people, 96.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Osteoporosis while taking Letrozole?

You are not alone! Join a mobile support group:
- support group for people who take Letrozole and have Osteoporosis
- support group for people who take Letrozole
- support group for people who have Osteoporosis

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    Anyone have anything or any experience that is remotely similar?

More questions for: Letrozole, Osteoporosis

You may be interested at these reviews (Write a review):

  • Bone pain whilst taking letrozole
    Before having breast cancer I walked 10 miles a week, and did a 40 min exercise
    routine. Having had a lumpectomy followed by 15 radiation treatments, and then
    prescribed letrozole for 10 years, I can no longer do my 40 min exercise routine, nor the power walking that I have done for so many years.
    I suffer severe bone pain and fatigue.
    I have come off the medication (3 wks now) after taking letrozole for 6mths.
    I can no longer tolerate the awful side affects, and Im just hoping the cancer
    does not come back.
  • Fosamax causes numerous problems (1 response)
    I took Fosamax for 7 years. In the last two years my bone decreased, where as it had been 28% loss in the spine it went to 31% loss. For the first 5 years it did stop any bone loss but later seemed to stop working. I was very lucky with this drug as others have numerous problems. one lady I know was developing sclerosis of the liver with this drug. There are numerous problems people can have.
  • Paxil cause osteoporosis?
    I had OCD since age 8. At 42 I was finally diagnosed and put on Paxil. When I reached 40 mgs and after 2 months on 40 mgs i was completely cured of OCD. I stayed on Paxil for the next 15 years. I no longer take any SSRI as they were causing severe lethargy that last few years of use. When I was around 47 I broke my wrist and then learned I was close to full blown osteoporosis. Five years ago I broke my humerus and then found that not only did I have osteoporosis but to a degree of a woman of 80. I had Prolia infusion 2 years ago and it reversed my bone loss. Last year my density test showed I was losing bone again and I had a Reclast infusion. I will not know if this has helped until next year. I am fairly sure that the Paxil had some fault in my osteoporosis although I know that my vitamin D levels are very low even after 50,000 units a week. I am not sure if is a combination effect of Paxil and low vitamin D that caused premature osteoporosis. No one in my family has had osteoporosis and no one that I am aware of has taken a SSRI.
  • Tinnitus with letrozole
    Sudden onset of ringing in the ears after two weeks on Letrozole 2.5mgs
  • Pain in the neck and arthritis after taking generic fosamax
    I started taking Generic Fosamax about six months ago and last week i had a terrible neck pain and spasm. I went to my accupunturist and he did accupunture and massage, but the pain did not go away. Later that week, I noticed that I had a lot of pain every time I flexed my left knee, and later that same day it started to sweell, like in people who have rheumatoid arthritis. I took my last dose of Generic Fosamax last Fryday, and I am wondering if it is the cause of my ailments. I am a healthy person, I exercise regularly and always eat healthy. I wwent again to my accupunturist yesterday and he ordered an Xray of my knee. I would like to know if somebody has had my problems while taking Fosamax and how they got cured. Excuse my English, it is not my main language. Thank you.

More reviews for: Letrozole, Osteoporosis

Comments from related studies:

  • From this study (4 years ago):

  • I am to start Alendronic acid after finishing treatment for returned breast cancer - with such a contradicory assortment of medication I wnat to know how to keep the right balance - what to look for?

    Reply

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