Review: could Lexapro cause Serotonin Syndrome?


Serotonin syndrome is found among people who take Lexapro, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Ambien, and have Depression . We study 41,077 people who have side effects while taking Lexapro from FDA and social media. Among them, 166 have Serotonin syndrome. Find out below who they are, when they have Serotonin syndrome and more.

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Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. (latest outcomes from Lexapro 43,172 users)

Serotonin Syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with disease complication, insomnia, feeling jittery, vaginal discharge, bruxism (latest reports from 7,123 Serotonin syndrome patients).

On Aug, 23, 2016

41,077 people reported to have side effects when taking Lexapro.
Among them, 166 people (0.4%) have Serotonin Syndrome

Number of reports submitted per year:

Could Lexapro cause Serotonin syndrome?

Time on Lexapro when people have Serotonin Syndrome *:

  • < 1 month: 59.15 %
  • 1 - 6 months: 21.13 %
  • 6 - 12 months: 4.23 %
  • 1 - 2 years: 1.41 %
  • 2 - 5 years: 12.68 %
  • 5 - 10 years: 1.41 %
  • 10+ years: 0.0 %

Gender of people who have Serotonin Syndrome when taking Lexapro *:

  • female: 74.19 %
  • male: 25.81 %

Age of people who have Serotonin Syndrome when taking Lexapro *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.94 %
  • 20-29: 18.25 %
  • 30-39: 17.46 %
  • 40-49: 16.67 %
  • 50-59: 14.29 %
  • 60+: 25.4 %

Severity if Serotonin Syndrome when taking Lexapro **:

  • least: 0.0 %
  • moderate: 66.67 %
  • severe: 0.0 %
  • most severe: 33.33 %

How people recovered from Serotonin Syndrome **:

  • while on drug: 66.67 %
  • after off the drug: 0.0 %
  • not yet: 33.33 %

Top conditions involved for these people *:

  • Depression (69 people)
  • Anxiety (18 people)
  • Insomnia (14 people)
  • Seizures (6 people)
  • Bipolar Disorder (6 people)

Top co-used drugs for these people *:

  • Ambien (13 people)
  • Zoloft (12 people)
  • Zyvox (11 people)
  • Wellbutrin (11 people)
  • Geodon (9 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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