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Review: could Lisinopril cause Angioedema?

We study 93,588 people who have side effects while taking Lisinopril from FDA and social media. Among them, 1,663 have Angioedema. Find out below who they are, when they have Angioedema and more.

Get connected: join a mobile support group for people who take Lisinopril and have Angioedema >>>


Lisinopril (latest outcomes from 99,013 users) has active ingredients of lisinopril. It is often used in high blood pressure.


Angioedema (rapid swelling of the dermis) (latest reports from 59,101 patients) has been reported by people with high blood pressure, pain, diabetes, high blood cholesterol, type 2 diabetes.

On Oct, 13, 2014: 93,588 people reported to have side effects when taking Lisinopril. Among them, 1,663 people (1.78%) have Angioedema.

Trend of Angioedema in Lisinopril reports

Time on Lisinopril when people have Angioedema * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Gender of people who have Angioedema when taking Lisinopril * :


Age of people who have Angioedema when taking Lisinopril * :


Severity of Angioedema when taking Lisinopril ** :

leastmoderateseveremost severe

How people recovered from Angioedema ** :

while on the drugafter off the drugnot yet

Top conditions involved for these people * :

  1. Hypertension (1,160 people, 69.75%)
  2. Diabetes mellitus (48 people, 2.89%)
  3. Pain (41 people, 2.47%)
  4. Cardiac failure congestive (18 people, 1.08%)
  5. Prophylaxis (16 people, 0.96%)

Top co-used drugs for these people * :

  1. Aspirin (127 people, 7.64%)
  2. Hydrochlorothiazide (89 people, 5.35%)
  3. Simvastatin (77 people, 4.63%)
  4. Atenolol (43 people, 2.59%)
  5. Amlodipine (40 people, 2.41%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

Comments for this study:

Rjs (4 years ago):

Your statistics are not
corrected for frequency of use and are therefore misleading.
Reply the comment

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Angioedema while taking Lisinopril?

Get connected! Join a mobile support group:
- support group for people who take Lisinopril and have Angioedema
- support group for people who take Lisinopril
- support group for people who have Angioedema

Comments from related studies:

  • From this study (1 year ago):



  • From this study (3 years ago):

  • I'm a stage IV Lupus Nephritis patient, currently trying to rescue my kidneys from end stage renal failure. Within 2 weeks of being on lisinopril for my elevated blood-pressure and hypertension, I started having this frightening allergic reaction where my entire face would swell up to the point where I looked like the offspring of an alien and a cabbage patch doll. Eyes, cheeks, lips, chin so swollen I didn't recognize myself in the mirror. We thought perhaps it was a reaction to the anemia shots I was going in for but when checked out, my doc immediately knew it was angioedema..something which I'd never heard of...and lisinopril was his immediate suspect. The warnings say this is a very uncommon thing, however, the statistics I've found on lisinopril put angioedema at the top of the side effect list. Moreover, it's hard on the kidneys and can actually cause kidney damage, which is why I'm in this boat to begin with. Anyway, at my doc's approval I've stopped the lisinopril and 2 days later I'm already noticing the swelling is less severe and this crap is leaving my system hopefully before it can do more damage. Idiots...


  • From this study (3 years ago):

  • on med for only 3 months, lips, tongue and throat swelled, Could not swallow or speak from swellingm of the throast, could only get out whispers. Started having trouble breathing, called 911 and was given IV in ambulance and drugs to help me breathe. Taken to hospital and kept overnight and given more meds to help ease the swelling. Was released the next day with prescriptions for steroids, pepcid and an epi pen. Was a severe and horrible experience. The doctor told me to immediately stop the lisinipril 10 mg, that it was known to cause this allergic reaction even after taking it for long periods of time.


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More reviews for: Lisinopril, Angioedema

On eHealthMe, Lisinopril (lisinopril) is often used for high blood pressure. Find out below the conditions Lisinopril is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Lisinopril used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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