Review: could Lisinopril cause Withdrawal Syndrome?


Withdrawal syndrome is found among people who take Lisinopril, especially for people who are female, 60+ old also take medication Lyrica, and have Hypertension . We study 117,180 people who have side effects while taking Lisinopril from FDA and social media. Among them, 229 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. (latest outcomes from Lisinopril 170,811 users)

Withdrawal Syndrome

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, back pain, muscle spasticity (latest reports from 13,480 Withdrawal syndrome patients).

On Oct, 26, 2016

117,180 people reported to have side effects when taking Lisinopril.
Among them, 229 people (0.2%) have Withdrawal Syndrome

Number of reports submitted per year:

Could Lisinopril cause Withdrawal syndrome?

Gender of people who have Withdrawal Syndrome when taking Lisinopril *:

  • female: 55.41 %
  • male: 44.59 %

Age of people who have Withdrawal Syndrome when taking Lisinopril *:

  • 0-1: 0.0 %
  • 2-9: 0.54 %
  • 10-19: 0.54 %
  • 20-29: 1.08 %
  • 30-39: 5.38 %
  • 40-49: 19.35 %
  • 50-59: 29.57 %
  • 60+: 43.55 %

Top conditions involved for these people *:

  • Hypertension (100 people, 43.67%)
  • Pain (56 people, 24.45%)
  • Depression (55 people, 24.02%)
  • Anxiety (44 people, 19.21%)
  • Diabetes Mellitus (26 people, 11.35%)

Top co-used drugs for these people *:

  • Lyrica (53 people, 23.14%)
  • Xanax (42 people, 18.34%)
  • Cymbalta (39 people, 17.03%)
  • Hydrochlorothiazide (30 people, 13.10%)
  • Seroquel (29 people, 12.66%)

Top other side effects for these people *:

  • Pain (42 people, 18.34%)
  • Headache (37 people, 16.16%)
  • Insomnia (35 people, 15.28%)
  • Anxiety (34 people, 14.85%)
  • Feeling Abnormal (33 people, 14.41%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Withdrawal syndrome when taking Lisinopril?

Browse all side effects of Lisinopril

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Withdrawal syndrome

Withdrawal syndrome

Could your condition cause Withdrawal syndrome

Withdrawal syndrome

Related studies

Can you answer these questions?

More questions for: Lisinopril, Withdrawal syndrome

You may be interested in these reviews

More reviews for: Lisinopril, Withdrawal syndrome

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.