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Review: could Lomotil cause Anxiety?

Summary: Anxiety could be caused by Lomotil, especially for people who are female, 60+ old, also take Zometa, and have Osteoporosis.

We study 5,734 people who have side effects while taking Lomotil from FDA and social media. Among them, 332 have Anxiety. Find out below who they are, when they have Anxiety and more.

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Lomotil (latest outcomes from 5,893 users) has active ingredients of atropine sulfate; diphenoxylate hydrochloride. It is often used in diarrhea, irritable bowel syndrome. Commonly reported side effects of Lomotil include diarrhea, diarrhoea aggravated, nausea, dehydration, fatigue.


Anxiety (latest reports from 1,274,338 patients) has been reported by people with depression, stress and anxiety, quit smoking, multiple sclerosis, pain.

On Apr, 12, 2014: 5,734 people reported to have side effects when taking Lomotil. Among them, 348 people (6.07%) have Anxiety. They amount to 0.03% of all the 1,290,794 people who have Anxiety on eHealthMe.

Trend of Anxiety in Lomotil reports

Time on Lomotil when people have Anxiety * :


Gender of people who have Anxiety when taking Lomotil * :


Age of people who have Anxiety when taking Lomotil * :


Severity of Anxiety when taking Lomotil ** :


How people recovered from Anxiety ** :


Top conditions involved for these people * :

  1. Osteoporosis (38 people, 10.92%)
  2. Pain (36 people, 10.34%)
  3. Multiple myeloma (33 people, 9.48%)
  4. Anxiety (31 people, 8.91%)
  5. Diarrhoea (31 people, 8.91%)

Top co-used drugs for these people * :

  1. Zometa (165 people, 47.41%)
  2. Zofran (132 people, 37.93%)
  3. Ambien (128 people, 36.78%)
  4. Prilosec (125 people, 35.92%)
  5. Lasix (123 people, 35.34%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Lomotil, Anxiety

You can also:

On eHealthMe, Lomotil (atropine sulfate; diphenoxylate hydrochloride) is often used for diarrhea. Find out below the conditions Lomotil is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Lomotil used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (4 days ago):

  • had stent put in about 2 months ago, have been on several medicines, they have been changed several times since, wore nicotine patch for about a month but removed it


  • From this study (4 days ago):

  • This is a new med, given in place of keppra xl


  • From this study (1 week ago):

  • I have been off zoladex for 8 months now, after having it for 2 years. I got my periods back, but not a normal cycle. i still get hot flushes at times. I am currently suffering from anxiety and fatigue. Can they be due to zoladex withdrawal? thanks


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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Related study

- Lomotil side effects


Related symptom

- Anxiety



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