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Review: could Losartan cause Irritability?

Summary: Irritability is found among people who take Losartan, especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years, also take medication Losartan potassium, and have High blood pressure.

We study 13,003 people who have side effects while taking Losartan from FDA and social media. Among them, 37 have Irritability. Find out below who they are, when they have Irritability and more.

You are not alone: join a mobile support group for people who take Losartan and have Irritability >>>

 

 

 

 

Losartan

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. (latest outcomes from 14,091 Losartan users)

Irritability

Irritability has been reported by people with depression, quit smoking, pain, stress and anxiety, attention deficit hyperactivity disorder. (latest reports from 23,559 Irritability patients)

On Feb, 3, 2015: 12,974 people reported to have side effects when taking Losartan. Among them, 37 people (0.29%) have Irritability.

Trend of Irritability in Losartan reports

Time on Losartan when people have Irritability * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Irritability0.00%28.57%0.00%42.86%28.57%0.00%0.00%

Gender of people who have Irritability when taking Losartan * :

FemaleMale
Irritability69.44%30.56%

Age of people who have Irritability when taking Losartan * :

0-12-910-1920-2930-3940-4950-5960+
Irritability0.00%3.23%0.00%0.00%9.68%6.45%45.16%35.48%

Severity of Irritability when taking Losartan ** :

leastmoderateseveremost severe
Irritability0.00%100.00%0.00%0.00%

How people recovered from Irritability ** :

while on the drugafter off the drugnot yet
Irritability0.00%50.00%50.00%

Top conditions involved for these people * :

  1. Hypertension (10 people, 27.03%)
  2. Depression (5 people, 13.51%)
  3. Hepatitis c (5 people, 13.51%)
  4. Sleep disorder (4 people, 10.81%)
  5. Blood cholesterol (4 people, 10.81%)

Top co-used drugs for these people * :

  1. Losartan potassium (31 people, 83.78%)
  2. Aspirin (7 people, 18.92%)
  3. Omeprazole (6 people, 16.22%)
  4. Hydrochlorothiazide (6 people, 16.22%)
  5. Ribavirin (5 people, 13.51%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Irritability while taking Losartan?

You are not alone! Join a mobile support group:
- support group for people who take Losartan and have Irritability
- support group for people who take Losartan
- support group for people who have Irritability

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

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    I've been on Losartan for a year without any problem. Six weeks ago I started on 25mg of Zoloft for general anxiety. All of a sudden during cardio exercise I feel lightheadedness and a feeling like I could pass out! I stop for a moment and then I feel ok. Is this normal? I thought I'd be getting more used to it after 6 weeks, but this is something new so I figured that it is now in my body and fatigue is normal. Or perhaps taking bp meds and Zoloft might be the cause.
  • Which is the preferred blood pressure med. to protect a 60+ diabetic type i w/ hypoglycemia unawareness. note ramipril after many years of use caused coughing - switched to losartan potassium - more (1 answer)
    Recently switched from Ramipril to Losartan Potassium since Ramipril was causing me to cough more and had been on this med. for years.
    Recently, have had 3 bad episodes of hypoglycemia esp. during the night. I was wondering if the BP med Losartan Potassium 25mg could be causing these? The BS levels have been very low in the 30-40 ranges. I have read the recent article of the study done on Losartan that women (esp. those 60+) maybe should not be on this med.
    I don't have elevated BP unless I see a doctor!! (Hx. of white coat syndrome) but my practitioner and former doctors want to protect my kidneys although no labs show a problem w/them. Any suggestions of any other BP med. that I could take that will not affect my blood sugar levels or cause me to cough!! I do have a history of MVP.
    Thanks so much for information you can share!
  • Up to two degree decrease in body temperature makes plasma donation an impossibility unless i drink 40 ozs of very not water. any suggestion?
    I've been donating plasma twice a week for over six years. Unfortunately the plasma center no longer allows a beta blocker, so I've been switched to an ACE inhibitor, Losartan 50 mg. This affects my body temperature, dropping it to 96 degrees and I cannot donate unless I chart at 97 degrees. I'm forced to drink piping hot water prior to donating in order to be within range. Is there an alternate solution, or would an Rx for Lisinopril be preferred. My research for the latter shows no one reporting hypothermia from Lisinopril. Thanks in advance.

More questions for: Losartan, Irritability

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    I had taken Ortho Novum 777 from the age of 18 to 28 stopping in-between pregnancies. I had 3 children between the ages of 21 and 29.

    In my early 30's I decided to stop taking birth control pills simply because I 'thought' it would be a healthier thing to do for my body. I did know that unless I was taking Ortho Novum that my period were not the standard 28 day routine. They were irregular and would be anywhere from 28 to 38 days. The longer the time in between periods the worse the pms symptoms would be. My theory is most likely because of the extended time between when I perceived a period and when I actually got it. It could very well have been psychosomatic but when my period would finally arrive, irritability and bloating would subside within a day or two. It was like a reset button and relief. I was calmer, more rational, even Kiel and motivated.

    In addition to the irregular pattern of my periods when off if birth control pills I also experienced pms twice a month. It would happen mid month when I was ovulating. The ovulation would be uncomfortable, I'd feel bloated again, and the cramps were painful. I'd move from ovulation week of irritability to PMS week of even greater irritability. I'd be waiting and counting down til my period was suppose to happen in anticipation of relief.

    I remember age 32 being significant for some reason. Upon reflecting back over the years while seeking treatment for a solution out of the psyco cycle I remember referring to age 32 as the year that things were never the same as they were in my 20's.

    Mid 30's I had asked my ob/gyn if I could go back on the Ortho Novum 777. I was told that I was too old. This was early 2000's, 2003 or 2004. I was given a different birth control pill that he recommended and I tried that for a while but it wasn't making things better and I don't remember the exact details. I tried bio identical hormones... That wasn't really helpful either, it was more work and a long process that I stuck with for at least a year trying to get the formula right. I finally threw the towel in on that.

    Then a different ob/gyn suggested I try progesterone only. He prescribed a pink round ball of a pill. I was to take it the last 10 days of the month. I tried that for 3 or 4 months, it wasn't making things better... in fact I think it made it worse. Then I went cold turkey again for the better part of a year. At age 37, after not finding a doctor that was helping the situation I decided to find a doctor in AZ. I live full time in CA but had a vacation home in AZ so I thought I'd try that for a change.

    I did find a doctor and she prescribed yaz 24 day. She said it should help me as it has helped many other women. I took the yaz for a little better than a year and psychologically I thought I had a winner! This doctor sounded like she knew my problems and that this was the solution. Alas it was not. I remember feeling the most depressed is ever felt. I didn't think it had anything to do with the yaz, I figured it was just life. When I returned to that doctor after a year I explained my situation. She then recommended that I get an ablation!?! I was never a heavy bleeder and it makes no sense to have that done, but she sold me on the idea that it would help my problem. I realize now she was doing exactly that, selling. I'm sure it was a nice payment from the insurance company.

    None of my issues were solved. I had stopped taking the yaz or any birth control at that point. My period were non existent after boiling my uterus in boiling water, which is what the ablation is. And to this day my period is hardly worth talking about or being prepared for. It's spotting for a couple 3 days at best. With regard to my symptoms, the pms, pmdd, extreme irritability, depression all that stayed the same. I tried Seasonal for about 2 months and that was not good, it seemed to 'amp' the 'hot' - not physically hot but an irritable term I use to describe the upped level my nerves set at.

    I did exercise pretty regularly during all if this. The times I wasn't exercising were over the top as far as pmdd symptoms so that motivates you to get your rear to the gym. On the Yaz 24 day I knew something wasn't right. At day 14 I'd feel the symptoms if ovulation, not imagined but real. I was slightly irritable and had cramps for 2 to 3 days. At day 17, a Wednesday the irritability would ramp up and the depression would start to be present for the next 2 weeks.

    The following Wednesday was day 24, that was the last day of taking the pill. I did get a bit of relief after stopping the pill and 4 days later I resumed taking the next months pack on Sunday. The thing is I wouldn't get my period until Tuesday after I started the new pack? I know that my period should have happened between day 24 and 28 but it never did. It always started on day 31 or 32 and lasted 2 to 3 days. Then the whole cycle begins again with day 14.

    On Yaz 24

    Day 1 Sunday
    Day 3 or 4 Tuesday and my period would start.
    Day 5 or 6 my period ended
    Day 14 - Day 17 ovulation type cramping
    Day 17 irritability started ramping up into PMS, PMDD & Depression
    Symptoms were worse without exercise by at least 40%
    Day 24 Wednesday, last day of Yaz pack for the month
    Day 25 slight mood improvement
    Day 30-31 (same as Day 3/4above) period would start

    The ob/gyn expertise wasn't working, male or female. I went to my regular general practitioner for a check up and had done much research on the type of hormones in the Yaz, Yasmin and many others. I was convinced that I need to move over to Yasmin 21 day. It had a but more estrogen and it was only 21 instead of 24 days so worth a try.

    She asked me when the last time I felt 'normal' with regard to the hormones. I told her that as far as I can recall it was when I was in my 20's when I was taking the Ortho Novum 777. She said why don't we have you start taking that again! I was like, what? I explained I was told I could not take that because of my age and I thought some doctor had told me it had been discontinued years ago anyway. She said no, I can prescribe it to you, it's still available. I was a little excited about that. Maybe... just maybe that would be a solution for relief. My blood pressure is 100/70 always has been low, I don't smoke and I'm 5' 8", 150 pounds. She saw no reason for me not to try it again. We agreed that I would and if it didn't go well we'd try the Yasmin.

    I've been in the Ortho Novum, my package and brand saying Alyacen 7/7/7 for 3 weeks now. Today is Sunday and I stop taking active pills for 7 days now. At day 7 or so I noticed how much easier it was becoming to get out of bed in the morning. I began noticing I had an interest in getting something done. I didn't have a big heavy cloud urging me to just stay in bed. I started feeling alive again.

    The jury is still out and I have ordered a second months supply but I am deeply encouraged. During week 3 I have been crampier than on the yaz but in a very normal feeling way. Like my body is preparing for menstruation. I'm anticipating bleeding heavier than I'm used to, but in a good way. The cramping has been something I definitely notice much much more so but it's manageable. What I also notice is lack...... huge overwhelming lack of that horrible irritability. I'm more sensitive than weeks one and two but it's nothing by comparison. I've been more level headed, more 'normal'. Time will tell if this is my cure for the next 6 or so years but I'm extremely encouraged right now. I literally feel the best I have in years and there is some pretty crapy stressful things going on in my life. But I can handle them-

    Side note, I am a Type A personality. I am under a lot of stress running my own business often. I am a mother of 3 and a very capable woman. Watch out world if I'm back like my 20's nothing will stop me. I'm positive, excited and thankful for this moment.

    It stinks if this is this truly is the solution to my problem, as years of my life and those around me have been effected. But it does no good to look back I'm looking forward with great anticipation!

    Good Luck, I hope this monologue can help someone else just like me and I'll be saving a copy for future female generations of mine.

    God Bless

More reviews for: Losartan, Irritability

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