Review: could Lyrica cause Memory loss?
Summary: Memory loss is found among people who take Lyrica, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Neurontin, and have Fibromyalgia.
We study 64,375 people who have side effects while taking Lyrica from FDA and social media. Among them, 2,155 have Memory loss. Find out below who they are, when they have Memory loss and more.
You are not alone: join a mobile support group for people who take Lyrica and have Memory loss >>>
Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from 66,581 Lyrica users)
Memory loss has been reported by people with multiple sclerosis, depression, pain, high blood pressure, high blood cholesterol. (latest reports from 63,324 Memory loss patients)
On Jan, 27, 2015: 64,375 people reported to have side effects when taking Lyrica. Among them, 2,155 people (3.35%) have Memory Loss.
Time on Lyrica when people have Memory loss * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Memory loss||44.98%||24.88%||10.54%||11.70%||6.59%||0.82%||0.49% |
Gender of people who have Memory loss when taking Lyrica * :
|Memory loss||73.99%||26.01% |
Age of people who have Memory loss when taking Lyrica * :
|Memory loss||0.00%||0.00%||0.42%||2.47%||8.43%||23.12%||27.12%||38.44% |
Severity of Memory loss when taking Lyrica ** :
|least||moderate||severe||most severe |
|Memory loss||7.27%||50.91%||34.55%||7.27% |
How people recovered from Memory loss ** :
|while on the drug||after off the drug||not yet |
|Memory loss||12.00%||0.00%||88.00% |
Top conditions involved for these people * :
- Fibromyalgia (660 people, 30.63%)
- Pain (485 people, 22.51%)
- Neuralgia (376 people, 17.45%)
- Neuropathy peripheral (196 people, 9.10%)
- Hypertension (192 people, 8.91%)
Top co-used drugs for these people * :
- Neurontin (326 people, 15.13%)
- Cymbalta (255 people, 11.83%)
- Ambien (197 people, 9.14%)
- Xanax (182 people, 8.45%)
- Nexium (180 people, 8.35%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Memory Loss while taking Lyrica?
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- support group for people who take Lyrica and have Memory Loss
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- support group for people who have Memory Loss
Recent conversations of related support groups:
- Support group for people who take Lyrica
I have gained about 35 pounds, and I have the cognitive effects listed in the prescribing information--problems with thinking and concentration." I've been off Lyrica once, and the side effects went away, but I couldn't get out of bed in the morning
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After the extreme weight gain. The dizziness. The exhaustion all the time. Nausea consistently before, during and after eating. Extreme lower back pain. Leg pain, cramping, and jerking. Now her oxygen levels are from 82-95 tops with the bi-pap. She finally wants to quit taking Lyrica, cymbalta, forteo, and all the prescription stomach meds she has to take because she's on them. I am figuring lowering 25 mgs at a time and staying there for 28 days with the Lyrica. She's been on Lyrica and cymbalta for 5-1/2 years. Any help would be greatly appreciated. I know with the severity of her problems she will not make it another three years. The confusion she's in approximately 70% of the time I'm going to lose her. She woke up and was totally confused while I was in the restroom for a couple minutes and I wound up rushing her to the hospital where she died in my arms before bringing her back three times because she took 17-15 mg oxycodone thinking they were her night pills. The reason I'm going into so much detail is to show the severity. Every doctor I've spoken with has said 25-50 mgs for two weeks is the norm. I told her doctor when he bumped her from 75 to 150 she wouldn't be able to take it. I am absolutely positive her body will go through major withdrawals and I can't have that happen. Thank you for taking the time to read everything I've written.
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More questions for: Lyrica, Memory loss
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- Percocet and memory loss
A close friend of mine has been using prescription Percocet for 5 to 6 years. Her MD first prescribed the lowest dosage possible to be taken 3 to 4 times daily for pain. I am aware that this medication frequently needs to be increased because it will become less effective. I don't know how many times he has increased the dosage but it has been many times. I believe now she is taking the highest dosage of it up to four to six times daily and six tablets at a time. I have made several attempts to tell her the information I know about Percocet and to have her to ask her MD about her now short and long term memory problems. Her response is to shout at me, telling me she needs that much for pain and to mind my own business when I tell her about the negative side effects I see, especially her daily and hourly memory problems. She has also said she has no reason to speak to her doctor about memory problems. I think that is because she fears he might lower the dosage. My concern about her poor memory only causes her to tell me I am the one with a bad memory, even though the only pain meds I infrequently take are OTC ones. According to my MD, I have been told my memory for my age of 63 is perfectly fine and better than most for my age. Also I take no medications with the side effects that cause memory problems. In addition when my MD prescribes new medication I always read the info that accompanies them, do research online and pay attention to all warnings and side effect info. The few times I have had side effects they have only been GI problems and I have consulted my MD regarding those and work with my MD for an alternative medication. My friend NEVER EVER reads any of the accompanying material that comes with her prescriptions. Also she never looks up her medications online to get additional information, including possible side effects. I worry about her very much and fear she now has an addiction to Percocet. Several years ago she asked her MD for Chantix to stop smoking, never reading the info supplied with the prescription. I urged to read the info and side effects. She declined, telling me she knew what she was doing. After two weeks of using Chantix she had a mental break down and ended up on the psych ward of our local hospital for 3 weeks. That medication was the first that began to cause her to have memory problems. She accepted that fact for about a month then dismissed it claiming her memory problems were over. They weren't because she was still taking Percocet. I understand no one wants to be told by a friend they suspect that person has memory problems, but I haven't done so to be mean or cruel, but only out of great love and concern. At this point with all the Percocet she takes daily she really is at a level to be considered an addict and I fear soon she will convince her MD to increase the dosage because it no longer controls her pain. I've written this review as a cautionary tale to inform others to be vigilant with their family, friends and loved ones as Percocet can and does cause short and long term memory loss. Although all my efforts to assist and speak to my friend have failed, please don't give up on those in your life who you notice are experiencing memory loss signs that take Percocet. If possible speak to them or their MD. Oh, and be prepared to be yelled at that you are the one with memory problems or to be told to mind your own business. And please, please read the information that accompanies all of your medications.
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Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.
The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.
The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.
It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.
There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.
Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.
The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).
Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.
I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
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Comments from related studies:
From this study (2 months ago):
ALTHOUGH SOMEWHAT NOTICING SOME SMALL LOSS OF MEMORY, COMMON TO 82 YEARS OF AGE, HE RAPIDLY DECLINED ON FIRST TAKING LYRICA. DOCTOR SAYS THAT A YEAR OLD MRI SHOWED SOME SMALL BRAIN CHANGES, BUT FAMILY WAS TOLD THAT RESULTS WERE ok
From this study (6 months ago):
Dizzy, depression, feelings of worthlessness
From this study (8 months ago):
Started Lyrica in mid-February 2014 for anxiety. Suffered stroke from vertebral artery dissection causing Lateral Medullary Syndrome in March 2014. Two months after stroke, memory impairment is growing. It is suspected that this impairment is a result of side-effect from Lyrica use and not caused by recent stroke or syndrome. Is memory impairment a typical side-effect of Lyrica? Was taking 50mg twice daily and was told by my doctor to reduce to 25mg twice daily to see if memory issues improve over the next couple of weeks. Will be re-assessed by neurologist in early June 2014.
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