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Review: could Lyrica cause Restless legs syndrome?

Summary: Restless legs syndrome could be caused by Lyrica, especially for people who are female, 50-59 old, have been taking the drug for < 1 month, also take Neurontin, and have Pain.

We study 64,173 people who have side effects while taking Lyrica from FDA and social media. Among them, 189 have Restless legs syndrome. Find out below who they are, when they have Restless legs syndrome and more.

On Apr, 11, 2014: 64,173 people reported to have side effects when taking Lyrica. Among them, 189 people (0.29%) have Restless Legs Syndrome. They amount to 0.28% of all the 67,332 people who have Restless Legs Syndrome on eHealthMe.

Trend of Restless legs syndrome in Lyrica reports

Time on Lyrica when people have Restless legs syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Restless legs syndrome37.93%31.03%6.90%0.00%13.79%6.90%3.45%

Gender of people who have Restless legs syndrome when taking Lyrica * :

FemaleMale
Restless legs syndrome72.56%27.44%

Age of people who have Restless legs syndrome when taking Lyrica * :

0-12-910-1920-2930-3940-4950-5960+
Restless legs syndrome0.00%0.00%0.00%0.71%11.43%26.43%33.57%27.86%

Severity of Restless legs syndrome when taking Lyrica ** :

leastmoderateseveremost severe
Restless legs syndrome0.00%20.00%80.00%0.00%

How people recovered from Restless legs syndrome ** :

while on the drugafter off the drugnot yet
Restless legs syndrome0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Pain (45 people, 23.81%)
  2. Fibromyalgia (43 people, 22.75%)
  3. Osteoporosis (22 people, 11.64%)
  4. Depression (21 people, 11.11%)
  5. Neuropathy peripheral (17 people, 8.99%)

Top co-used drugs for these people * :

  1. Neurontin (42 people, 22.22%)
  2. Amitriptyline hcl (34 people, 17.99%)
  3. Aredia (34 people, 17.99%)
  4. Acyclovir (33 people, 17.46%)
  5. Cymbalta (32 people, 16.93%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Lyrica, Restless legs syndrome

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Comments from related studies:

  • From this study (5 days ago):

  • I have chiari (decompressed), Syringomyelia, Intracranial hypertension, Tethered cord (surgery), CranioCervical Instability, Ehlers Danlos with mixed connective tissue disorder, crohns, afib, superventricular tachycardia and mast cell activation disorder

    Reply

  • From this study (1 week ago):

  • took lyrica for 10 days had allergic reaction plus Bilateral swelling of legs and hands with severe buring pain and numb hands. Did not have before lyrica now just diagnosed with sjogrens. Could lyrica have caused this? Also developed bilateral carpal tunnel hands slowing coming back after stopping lyrica.

    Reply

  • From this study (3 weeks ago):

  • Weakened immune system, still recovering from major surgery. Developed pneumonia. Began lyrica and found first large area on my chest that looked like it had been severely chemically burned. Doctor prescribed muciprin (sp?) developed many more sores on face, arms, back, and chest over the next month. Went back to doctor. Prescribed am-trak orally 5 days. Great improvement while on it, day after ending the antibiotic all the sores opened back up. Began to look less burn-like and more crater like. Not overly red or swollen. Would go from nothing to big something within 24 hours. Back to doctor after I tried tons of home remedies like essential oils, tea tree oil, and apple cidar vinegar. Next he prescribed bactrim orally for 7 days. No improvement first few days. Then I dropped my lyrica from 300 mg/day to 100 mg/day, while continuing antibiotic. Great improvement. Dried up and smaller ones healed. Finished antibiotic and all sores that weren't totally healed reopened, as well as the new sores forming. I do not pick at them. No doctor has cultured them. I have been going to physical therapy 2 days a week for 5 months now. I have not actually been diagnosed with mrsa, but that is what it looks like it has turned into to me. It did not start off this way. 5 months ago it began with some burns & blisters on my chest and face. Now they look like sores.

    Reply

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