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Review: could Lyrica cause Restless legs syndrome (Restless leg syndrome)?

We study 64,287 people who have side effects while taking Lyrica from FDA and social media. Among them, 190 have Restless legs syndrome. Find out below who they are, when they have Restless legs syndrome and more.

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Lyrica

Lyrica (latest outcomes from 66,494 users) has active ingredients of pregabalin. It is often used in fibromyalgia.

Restless legs syndrome

Restless legs syndrome (a powerful urge to move your legs) (latest reports from 68,722 patients) has been reported by people with restless leg syndrome, osteoporosis, depression, high blood pressure, pain.

On Sep, 14, 2014: 64,287 people reported to have side effects when taking Lyrica. Among them, 190 people (0.30%) have Restless Legs Syndrome.

Trend of Restless legs syndrome in Lyrica reports

Time on Lyrica when people have Restless legs syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Restless legs syndrome40.00%30.00%6.67%0.00%13.33%6.67%3.33%

Gender of people who have Restless legs syndrome when taking Lyrica * :

FemaleMale
Restless legs syndrome72.69%27.31%

Age of people who have Restless legs syndrome when taking Lyrica * :

0-12-910-1920-2930-3940-4950-5960+
Restless legs syndrome0.00%0.00%0.00%0.71%11.35%26.24%34.04%27.66%

Severity of Restless legs syndrome when taking Lyrica ** :

leastmoderateseveremost severe
Restless legs syndrome0.00%33.33%66.67%0.00%

How people recovered from Restless legs syndrome ** :

while on the drugafter off the drugnot yet
Restless legs syndrome0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Pain (45 people, 23.68%)
  2. Fibromyalgia (44 people, 23.16%)
  3. Osteoporosis (22 people, 11.58%)
  4. Depression (21 people, 11.05%)
  5. Neuropathy peripheral (17 people, 8.95%)

Top co-used drugs for these people * :

  1. Neurontin (42 people, 22.11%)
  2. Aredia (34 people, 17.89%)
  3. Amitriptyline hcl (34 people, 17.89%)
  4. Acyclovir (33 people, 17.37%)
  5. Cymbalta (32 people, 16.84%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Restless Legs Syndrome while taking Lyrica?

Get connected! Join a mobile support group:
- group for people who take Lyrica and have Restless Legs Syndrome
- group for people who take Lyrica
- group for people who have Restless Legs Syndrome

Comments from related studies:

  • From this study (1 day ago):

  • This drug does not help a person with social anxiety and or panic disorder. I was tired for the first couple of days but couldn't sleep due to restless leg. Now, after three weeks of taking it, I'm up til 2am. Does not help me sleep. I feel restless and tired/awake.

    Reply

    Thomas Mofield on Sep, 1, 2014:

    The FDA has approved Ambien (Zolpidem) as an off label treatment for restless leg syndrome. Ambien is a sedative and is used to help you sleep.

    A word of caution: Although zolpidem is used as an off label treatment for restless leg, sometimes it will make little difference, and sometimes it can make it worse (this is rare though). Give it a shot. Hope you get some restful sleep.

    I sometimes get restless leg, the only thing that helps me (oddly enough) is to sleep with my feet uncovered. I don't know why this works, but it does for me.

    Reply

  • From this study (1 day ago):

  • I have the crest variation of scleroderma. Since developing this illness in 2004 I have developed bone spurs on both feet, as well as my right hip and my right shoulder. I am just curious if Scleroderma and or any of the above medications induce bone spurs. Thank you. Shirley

    Reply

  • From this study (3 days ago):

  • Elavil, 25mg @ night stopped an 11 month chronic headache after a head injury, I sustained 1 1/2 years ago.
    Additionally, Neurologist prescribed 100 mg Lyrica for chronic back/nerve pain from moderate/severe spinal injuries, sustained 20+ years earlier. (Crushed/cracked verabrae and 3 intervertebral disc bulges)
    I had been using Ibuprofen daily in moderate to heavy dosage for the last 20+ years. (800+ mg daily B/4 and then continually after recent head injury)
    I was advised to stop/reduce use of Motrin to 1/2 month or less. It is still the best pain relief but have reduced to PRN, perhaps 200 mg alternate days.
    Since treatment with Lyrica I've noticed reduced nerve pain and stopped using Elavil for sake of not feeling so "wrecked" in the mornings. I have also developed a severe sleep apnoea, treated unsuccessfully via CPAP device which is unbearable to use. I have subsequently suffered with depression/mood disorder for 20+ years and am currently un-treated for this long-standing vulnerability which came back with a vengence after the head-injury. I feel irregularity to my heart beat by the end of the day. I feel suicidal and violently angry.

    Reply

    dutchgirlsamm on Aug, 30, 2014:

    Lyrics is known to cause suicidal thoughts and aggression...its called an adverse reaction.

    Reply

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