Review: could Lyrica cause Sexual dysfunction (Erection problems)?
Summary: Sexual dysfunction is found among people who take Lyrica, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take medication Neurontin, and have Pain.
We study 64,375 people who have side effects while taking Lyrica from FDA and social media. Among them, 321 have Sexual dysfunction. Find out below who they are, when they have Sexual dysfunction and more.
You are not alone: join a mobile support group for people who take Lyrica and have Sexual dysfunction >>>
Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from 66,581 Lyrica users)
Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity) has been reported by people with depression, high blood pressure, high blood cholesterol, pain, hair loss. (latest reports from 32,084 Sexual dysfunction patients)
On Jan, 12, 2015: 64,360 people reported to have side effects when taking Lyrica. Among them, 321 people (0.50%) have Sexual Dysfunction.
Time on Lyrica when people have Sexual dysfunction * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Sexual dysfunction||35.09%||15.79%||22.81%||17.54%||5.26%||3.51%||0.00% |
Gender of people who have Sexual dysfunction when taking Lyrica * :
|Sexual dysfunction||6.42%||93.58% |
Age of people who have Sexual dysfunction when taking Lyrica * :
|Sexual dysfunction||0.00%||0.00%||0.42%||1.27%||3.80%||14.35%||39.24%||40.93% |
Severity of Sexual dysfunction when taking Lyrica ** :
|least||moderate||severe||most severe |
|Sexual dysfunction||11.76%||5.88%||70.59%||11.76% |
How people recovered from Sexual dysfunction ** :
|while on the drug||after off the drug||not yet |
|Sexual dysfunction||0.00%||15.38%||84.62% |
Top conditions involved for these people * :
- Pain (57 people, 17.76%)
- Neuralgia (53 people, 16.51%)
- Multiple myeloma (31 people, 9.66%)
- Pain in extremity (30 people, 9.35%)
- Arthralgia (29 people, 9.03%)
Top co-used drugs for these people * :
- Neurontin (72 people, 22.43%)
- Zometa (67 people, 20.87%)
- Aspirin (58 people, 18.07%)
- Viagra (56 people, 17.45%)
- Aredia (54 people, 16.82%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Sexual Dysfunction while taking Lyrica?
You are not alone! Join a mobile support group:
- support group for people who take Lyrica and have Sexual Dysfunction
- support group for people who take Lyrica
- support group for people who have Sexual Dysfunction
Recent conversations of related support groups:
- Support group for people who take Lyrica
I have gained about 35 pounds, and I have the cognitive effects listed in the prescribing information--problems with thinking and concentration." I've been off Lyrica once, and the side effects went away, but I couldn't get out of bed in the morning
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Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.
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It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.
There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.
Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.
The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).
Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.
I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
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Comments from related studies:
From this study (2 years ago):
After 4 days taking 100 mg twice daily I am totally impotent. I can't get an erection no matter how hard I try. After this short of a period of time. Going to discuss further with doctor before going off of the medication.
This is a ridiculous side effect for men.
From this study (3 years ago):
I used to have sex every day some times twice when possible ,after about 2yrs on the meds testosrone level is .025 (none)Starting about june 2005 I lost all body hair including pubic and facial hair,in about 3 mnts went from daily shaving to once a month ,was started on testosrone therapy presently using 20 mgs a day.Still sex drive is very low I realy don't care if I have it but partner wants to. I am presently waiting to have both knees replaced . I also have 5 herneated discs in back 3in the neck that are inoperatal 2 in lower back are bad ,I can have them fused but am waiting as long as i can . The ones in neck make my hands swell and get very hot as high as 105 fairenhite this extremly painfull and i frequently end up sleeping in a chair.Ican give more info if required thankyou mc
Jim on May, 13, 2012:
I have chronic pain and degenerative disc disease. I have undergone 8 back surgeries. I am now 52 years old. I always loved sex and it was important part of my marriage. I can tell you from experience, your lack of sexual desire is partly from the drugs but in large measure it is simply the result of being in horrible pain all the time. My best advice is to make sure your testosterone levels are at top of the normal range. Second and most importantly, I can have super high testosterone but without sleep, it is as if it doesn't metabolize into my system. You MUST figure out how to sleep well. DO NOT wake yourself in the morning simply because you feel guilty being in bed so late. If you have a job and have to be there early, I have no advice. I am self employed so I have moved my schedule around. I only get good sleep between 5 am and 10am. I have no idea why but this seems to be a trend with individuals like you and me. I have taken methadone for pain for 10yrs. Follow my advice and it should help.
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