Review: could Lyrica cause Sleep disorder?
Summary: Sleep disorder is found among people who take Lyrica, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Neurontin, and have Pain.
We study 64,375 people who have side effects while taking Lyrica from FDA and social media. Among them, 498 have Sleep disorder. Find out below who they are, when they have Sleep disorder and more.
You are not alone: join a mobile support group for people who take Lyrica and have Sleep disorder >>>
Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from 66,581 Lyrica users)
Sleep disorder has been reported by people with depression, quit smoking, osteoporosis, pain, high blood pressure. (latest reports from 42,448 Sleep disorder patients)
On Jan, 11, 2015: 64,360 people reported to have side effects when taking Lyrica. Among them, 498 people (0.77%) have Sleep Disorder.
Time on Lyrica when people have Sleep disorder * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Sleep disorder||43.86%||26.32%||4.39%||11.40%||7.02%||7.02%||0.00% |
Gender of people who have Sleep disorder when taking Lyrica * :
|Sleep disorder||67.10%||32.90% |
Age of people who have Sleep disorder when taking Lyrica * :
|Sleep disorder||0.00%||0.00%||2.72%||3.40%||8.16%||16.55%||25.62%||43.54% |
Severity of Sleep disorder when taking Lyrica ** :
|least||moderate||severe||most severe |
|Sleep disorder||0.00%||0.00%||100.00%||0.00% |
How people recovered from Sleep disorder ** :
|while on the drug||after off the drug||not yet |
|Sleep disorder||0.00%||0.00%||100.00% |
Top conditions involved for these people * :
- Pain (121 people, 24.30%)
- Fibromyalgia (81 people, 16.27%)
- Neuralgia (72 people, 14.46%)
- Neuropathy peripheral (58 people, 11.65%)
- Multiple myeloma (43 people, 8.63%)
Top co-used drugs for these people * :
- Neurontin (72 people, 14.46%)
- Aspirin (69 people, 13.86%)
- Cymbalta (67 people, 13.45%)
- Ambien (62 people, 12.45%)
- Nexium (56 people, 11.24%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Sleep Disorder while taking Lyrica?
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- support group for people who take Lyrica and have Sleep Disorder
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- support group for people who have Sleep Disorder
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- Support group for people who take Lyrica
I have gained about 35 pounds, and I have the cognitive effects listed in the prescribing information--problems with thinking and concentration." I've been off Lyrica once, and the side effects went away, but I couldn't get out of bed in the morning
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- How much do i decrease at a time, and how long should the decrease last. lyrica, and symbalta
After the extreme weight gain. The dizziness. The exhaustion all the time. Nausea consistently before, during and after eating. Extreme lower back pain. Leg pain, cramping, and jerking. Now her oxygen levels are from 82-95 tops with the bi-pap. She finally wants to quit taking Lyrica, cymbalta, forteo, and all the prescription stomach meds she has to take because she's on them. I am figuring lowering 25 mgs at a time and staying there for 28 days with the Lyrica. She's been on Lyrica and cymbalta for 5-1/2 years. Any help would be greatly appreciated. I know with the severity of her problems she will not make it another three years. The confusion she's in approximately 70% of the time I'm going to lose her. She woke up and was totally confused while I was in the restroom for a couple minutes and I wound up rushing her to the hospital where she died in my arms before bringing her back three times because she took 17-15 mg oxycodone thinking they were her night pills. The reason I'm going into so much detail is to show the severity. Every doctor I've spoken with has said 25-50 mgs for two weeks is the norm. I told her doctor when he bumped her from 75 to 150 she wouldn't be able to take it. I am absolutely positive her body will go through major withdrawals and I can't have that happen. Thank you for taking the time to read everything I've written.
- Any information on deaths from taking lyica and high doses of alprazolam (1 answer)
My Mother was a healthy 89 yr old with no healt issues, she was put on anxiety medicine, which she took regularly. She was also taking Lyric and had just started her Macular degeneration shots. She was prone to bladder infections and we went to the dr. for that, labs showed high calcium, within one week I had to take her to the emergency room, within one day she was on oxygen, within three days she was in the ICU intubated and unresponsive. She remained in ICU for 4 days had renal failure and died two days later.
- Is pregabalin aggravate the symptoms of bph?
I am having BPH. for foot pain doctor prescribes Pregabalin. that night the symptoms of BPH worsens. Is it due to Pregabalin? pl.write.
- Can excessive consumption of marijuana cause sudden sleeping phobia which lasts longer (in days) ?
I have been taking marijuana since 2 years and sleep a lot. I always had sleeping disorder like, If someone is doing anything in my room, I can't sleep. I always think of something before sleeping and then I will have some random dream and sleep long if undisturbed. If someone wakes me up in the middle it takes time to go to sleep again. Generally I sleep around 2 AM and wake up at 12 PM. Four days ago I took marijuana for about 4 or five hours while watching movies (which I do very regularly) and went to bed. At 2:30 AM I felt kind of going in to darkness and highly afraid of the darkness, My heart rate was 142 and I was so afraid that I couldn't control my mind and got admitted to nearest hospital in ICU. They gave me sleeping pills and some drips (sodium chloride and some other injections). My blood report showed normal except 22.5 WBC which should be between 6 to 9. I didn't tell them that I have been smoking marijuana since I am a PhD student in my institute and they will simply throw me out if I do. Since that night I couldn't sleep without sleeping pills and whenever I try to, I feel the same terror and my heart bit starts increasing. During day time I feel highly anxious and uncomfortable. I want my old life back and I haven't smoked marijuana since that day and I promise not to. Please help me or I feel some night I will die while sleeping.
- Propranolo & pregabalin - do they produce heart troubles? my meds mix has
Being on zopiclone 75mg (sleep med) gave me terrible poly/firbomyalgia, which I was then prescrbed pregabalin to aleviate pains and anxiety, and the propranolo to help with the same. On day one of propranolo I had a medium heart attack like event, within 24hrs had a large attack and became hospitalised. But vital signs and chest xray, blood tests, then showed 'normal'. But since then have had several more (almost one or more a month) heart attacklike events, hospitalisation, etc, but still being told all 'normal'. But now I've met someone who has told me they had similar heart issues and were told professionally for years his vital signs were normal : he now has a tripple-heart-bypass. I keep being told the angina like symtoms I have are anxiety realted - "only". But when I look at the professional descriptions and illustrations of angina, and similar, I see I could have written and drawn those from my own experiences. Hellish! No where to turn to. So I'm stopping the meds now one by one in careful withdrawl - docs don't like it - but I'm convinced my meds are slowly degrading my overall health as they build up into a toxic soup in me. I started this withdrawly after I discovered that - officially - Pregabalin (a calcium ?minimiser) and Propranolol (a beta blocker) should not be taken together in case they cause heart malfunctions... shame my doctors didn't know that.... before they let me take them for 8 months!!!!!!
More questions for: Lyrica, Sleep disorder
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- Leg pain especially near knees after taking lyrica
Had to stop taking Lyrica due to joint pain in both legs. Difficult to get up from sitting position to stand. Ache in knee's can't relax to sleep. Motrin and vicodin not helping with pain. Also have applied muscle cream not working for pain. Have been off the lyrica for 3 months with no let up in pain. Did not have this pain before taking lyrica.
- 3 strong drugs together against neuropathic pain
Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.
The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.
The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.
It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.
There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.
Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.
The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).
Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.
I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
- Nexium improves my constipation
Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.
- Nightmare on lyrica st.
r.knee revision 3rd.and last time due from Mersa infection and blood clot left me 1 1/2 shorter on r. Leg. Lost a lot of nerves in foot lower r. Leg.bulging disc was from falling from knee revision and for 9 months had no knee and on crutches.had lots of falls and blew out lower back. Put me on lyrica 2 weeks ago now up to 120 mg.With perks 4 times a day. The title says it all when trying to sleep :( my dream hands down beat any horror movies and directors. 2 hours of sleep per night and overly beat down :(.the only 2 good things I have going,my since of silliness and the Lord :) I guess family also.so far not much help with meds but willingly and pos, that both will work, the Lord :) thanks and God bless
- Lyrica varied widely
I was prescribed Lyrica for treatment of chronic pain. It was ineffective, but it knocked out the symptoms of interstitial. However, it also caused rapid weight gain (I went from 110 to 130 lbs. in just a few weeks) and my ankles started to swell. The pain doctor advised me to discontinue the drug, but the urologist suggested lowering the dose. I did, and the swelling went down. I weighed myself daily and watched what I ate, and my weight returned to normal within a month. Subsequently, I continued taking the lower dose and had no further problems. Then I developed severe spinal stenosis, and my dosage of Lyrica was increased to six 75 capsules daily, in addition to 480 mg of morphine sulphate. I tolerated the Lyrica well. After surgery, however, my ankles began to swell again, and although I didn't have a problem with weight gain, I developed a bright red rash from ankles to knees. I dropped the dosage of Lyrica to 50 mg twice daily, and had no further side effects. The rash simply disappeared, with no damage to the skin. Following the surgery, I was able to titrate off morphine completely. I continue to take Lyrica twice daily. It doesn't seem to affect pain (I still ache a bit, as I have degenerative changes in all joints) but it does dampen peripheral neuropathy, which I experience both in my toes and balls of my feet. It also dampens the neuropathy in my forehead, where I had four surgeries to remove a malignant melanoma. I have had no side effects other than those mentioned, and find it interesting the I could tolerate a high dosage of Lyrica prior to surgery, but after surgery could not, and that adverse side effects varied not only with the dosage but with my own physical condition. I don't find it to be highly effective in treating neuropathy, but it does still the tingling enough to let me sleep and take my mind off the condition.
More reviews for: Lyrica, Sleep disorder
Comments from related studies:
From this study (4 months ago):
Sarcoidosis caused complete heart block. Pacemaker implanted in December 2009 but for the past two years I have had palpitations caused by around 3.7 million ectopic heartbeats per year.
Sarcoidosis also in lungs and eyes. Extended use of Pred Forte caused development of cataracts, one of which has been removed and I am awaiting the second operation.
Breathlessness is caused by lack of oxygen entering the bloodstream and my ongoing heart problems
Rarely able to sleep properly due to pain, sleeping for about 20 minutes at a time when I become so exhausted that the pain can't keep me awake
Muscle and joint pain have made me weak and clumsy.Pain is felt all over, from head to toes along with muscle cramps and intense burning sensation to skin on lower legs.
ACE levels fluctuate but average 110 - 150.
Blood pressure on average is 150 / 78 - no treatment given
I also take Nefopam Hydrochloride (Acupan) for pain but this drug is not on the list.
Immobility, fatigue and constant pain have left me very depressed ad harbouring thoughts of suicide. My 15 year old granddaughter has lived with me since the death of my daughter 11 years ago and it is my hope that I will live long enough to see her settled in college and independent after which the only thing I have to look forward to is to end my own suffering.
IchikireiLV on Sep, 5, 2014:
I was so sorry to read your comment, but glad I encountered it. PLEASE PLEASE don't ever think of taking your own life! I know what it is like to suffer. I injured myself 7 yrs ago, got a spinal implant that failed, compressed my spine, corroded and left me with heavy metal toxicity which caused adrenal failure, hypothyroid and many other serious health conditions. I have lived a life of chronic pain, fatigue and difficulty, so I know exactly where you are coming from! Some days I am so weak and have so much pain that I cannot get out of bed or care for myself. At times I try to puch myself to do the simplest things and my body is so frail I can barely catch my breath and feel like I gave to crawl back to my bed, dripping in sweat, dehydrated and defeated... but I still go on in hopes that there will be a better day. I ENCOURAGE YOU TO SEE A PAIN MANAGEMENT DR. MONTHLY FOR MEDICATIONS TO CONTROL YOUR PAIN! This alone will improve your daily life immensely! Pain will make you depressed! I also use Savella. It helps with Neuropathy pain AND DEPRESSION. Dont give up because doctors arent helping you enough. MAKE THEM! Its unacceptable that they are not following thru but I myself have experienced this many times.. Find another better, more compassionate Dr. Read Dr. reviews online, start with a primary care family dr, a pain dr and a rhuematologist for Sarcoidosis... make sure the Dr. is experienced with Sarcoidosis.. if not, find another one. I hope this helps you and gives you a direction to follow. Once your pain is controlled, things will be a lot better. Good luck and wishes of health and most of all HOPE and HAPPINESS 😄😄
Kath Nugent on Aug, 26, 2014:
I was diagnosed with Lymphatic Sarcoidosis 15 years ago. After massive weight loss, a node in my neck the size of a small egg, and at the same time an
area of my gum opened up were i had a tooth removed 20 years earlier, Sarcoid grew out of this opening !!it was like a piece of green string. My GP & Consultant tried to pull it out but failed,it was about an inch long. i was sent away with no further appointment, So i went to see my Dentist who seemed to know what it was and sent me to the Hospital Dentist who did a jaw bone Scraping and arranged for the node in neck to be removed for biopsy, both biopsy came back as Sarcoidosis. i was then x rayed and was found to have it in on my lungs as well. at this point i had active Sarcoidosis in my Lymphatic system, bone, lungs. However it as never been active in my lungs !!! it did however eat away the inside of my nose, it attacked my eyes i almost went blind, i lost my balance,it was in my brain.
i was so tired, and after so many steroids i was having a bad reaction to them in various organs and was taken of them. i did recover from this as the Sarcoid went dormant. i have recently been diagnosed with a brain tumor and raised platelets. given that Sarcoidosis is next door to Cancer and that i feel absolutely wasted and week!!! i am feeling anxious about the outcome of more tests. But we all have to go sometime and i know there are people out there worse than me !!! i send you all love & light and hope we can all have the strength to help each other through whatever is thrown at us!! not easy by any means. Happy to answer any questions if it will help anyone Take care Kath Nugent
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