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Review: could Lyrica cause Stevens-johnson syndrome?

Summary: Stevens-johnson syndrome could be caused by Lyrica, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Omeprazole, and have Neuralgia.

We study 64,173 people who have side effects while taking Lyrica from FDA and social media. Among them, 142 have Stevens-johnson syndrome. Find out below who they are, when they have Stevens-johnson syndrome and more.

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Lyrica

Lyrica (latest outcomes from 66,360 users) has active ingredients of pregabalin. It is often used in fibromyalgia, pain. Commonly reported side effects of Lyrica include pain exacerbated, pain, dizziness, dizziness aggravated, weight increased.

Stevens-johnson syndrome

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe) (latest reports from 134,802 patients) has been reported by people with convulsion, high blood pressure, epilepsy, ill-defined disorder, fever.

On Apr, 8, 2014: 64,116 people reported to have side effects when taking Lyrica. Among them, 142 people (0.22%) have Stevens-johnson Syndrome. They amount to 0.11% of all the 134,628 people who have Stevens-johnson Syndrome on eHealthMe.

Trend of Stevens-johnson syndrome in Lyrica reports

Time on Lyrica when people have Stevens-johnson syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Stevens-johnson syndrome81.16%13.04%1.45%4.35%0.00%0.00%0.00%

Gender of people who have Stevens-johnson syndrome when taking Lyrica * :

FemaleMale
Stevens-johnson syndrome53.38%46.62%

Age of people who have Stevens-johnson syndrome when taking Lyrica * :

0-12-910-1920-2930-3940-4950-5960+
Stevens-johnson syndrome0.00%0.81%0.00%0.00%8.87%12.10%33.87%44.35%

Severity of Stevens-johnson syndrome when taking Lyrica ** :

leastmoderateseveremost severe
Stevens-johnson syndrome0.00%0.00%0.00%100.00%

How people recovered from Stevens-johnson syndrome ** :

n/a

Top conditions involved for these people * :

  1. Neuralgia (28 people, 19.72%)
  2. Pain (24 people, 16.90%)
  3. Depression (22 people, 15.49%)
  4. Hypertension (19 people, 13.38%)
  5. Constipation (14 people, 9.86%)

Top co-used drugs for these people * :

  1. Omeprazole (15 people, 10.56%)
  2. Nexium (14 people, 9.86%)
  3. Lorazepam (14 people, 9.86%)
  4. Aspirin (13 people, 9.15%)
  5. Duragesic-100 (13 people, 9.15%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Lyrica, Stevens-johnson syndrome

You can also:

On eHealthMe, Lyrica (pregabalin) is often used for fibromyalgia. Find out below the conditions Lyrica is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Lyrica used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (1 week ago):

  • took lyrica for 10 days had allergic reaction plus Bilateral swelling of legs and hands with severe buring pain and numb hands. Did not have before lyrica now just diagnosed with sjogrens. Could lyrica have caused this? Also developed bilateral carpal tunnel hands slowing coming back after stopping lyrica.

    Reply

  • From this study (3 weeks ago):

  • Weakened immune system, still recovering from major surgery. Developed pneumonia. Began lyrica and found first large area on my chest that looked like it had been severely chemically burned. Doctor prescribed muciprin (sp?) developed many more sores on face, arms, back, and chest over the next month. Went back to doctor. Prescribed am-trak orally 5 days. Great improvement while on it, day after ending the antibiotic all the sores opened back up. Began to look less burn-like and more crater like. Not overly red or swollen. Would go from nothing to big something within 24 hours. Back to doctor after I tried tons of home remedies like essential oils, tea tree oil, and apple cidar vinegar. Next he prescribed bactrim orally for 7 days. No improvement first few days. Then I dropped my lyrica from 300 mg/day to 100 mg/day, while continuing antibiotic. Great improvement. Dried up and smaller ones healed. Finished antibiotic and all sores that weren't totally healed reopened, as well as the new sores forming. I do not pick at them. No doctor has cultured them. I have been going to physical therapy 2 days a week for 5 months now. I have not actually been diagnosed with mrsa, but that is what it looks like it has turned into to me. It did not start off this way. 5 months ago it began with some burns & blisters on my chest and face. Now they look like sores.

    Reply

  • From this study (3 weeks ago):

  • I am going to discontinue today to see if subsides.

    Reply

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