Review: could Macrobid cause Clostridium Difficile Colitis?


Clostridium difficile colitis is found among people who take Macrobid, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Lisinopril, and have Urinary tract infection . We study 4,326 people who have side effects while taking Macrobid from FDA and social media. Among them, 14 have Clostridium difficile colitis. Find out below who they are, when they have Clostridium difficile colitis and more.

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Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. (latest outcomes from Macrobid 4,894 users)

Clostridium Difficile Colitis

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) has been reported by people with multiple myeloma, high blood pressure, osteoporosis, pain, multiple sclerosis (latest reports from 6,129 Clostridium difficile colitis patients).

On Oct, 20, 2016

4,326 people reported to have side effects when taking Macrobid.
Among them, 14 people (0.32%) have Clostridium Difficile Colitis

Number of reports submitted per year:

Could Macrobid cause Clostridium difficile colitis?

Time on Macrobid when people have Clostridium Difficile Colitis *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Clostridium Difficile Colitis when taking Macrobid *:

  • female: 85.71 %
  • male: 14.29 %

Age of people who have Clostridium Difficile Colitis when taking Macrobid *:

  • 0-1: 0.0 %
  • 2-9: 7.69 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 7.69 %
  • 50-59: 38.46 %
  • 60+: 46.15 %

Top conditions involved for these people *:

  • Urinary Tract Infection (7 people, 50.00%)
  • Multiple Sclerosis (5 people, 35.71%)
  • Depression (5 people, 35.71%)
  • Hypertension (4 people, 28.57%)
  • Fatigue (4 people, 28.57%)

Top co-used drugs for these people *:

  • Lisinopril (5 people, 35.71%)
  • Uroxatral (4 people, 28.57%)
  • Provigil (4 people, 28.57%)
  • Phenergan (4 people, 28.57%)
  • Lexapro (4 people, 28.57%)

Top other side effects for these people *:

  • Urinary Tract Infection (4 people, 28.57%)
  • Rectal Ulcer (3 people, 21.43%)
  • Pain (3 people, 21.43%)
  • Muscle Spasms (2 people, 14.29%)
  • Fatigue (2 people, 14.29%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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