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Review: could Melatonin cause Anxiety?

Summary: Anxiety could be caused by Melatonin, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take Zometa, and have Pain.

We study 2,128 people who have side effects while taking Melatonin from FDA and social media. Among them, 145 have Anxiety. Find out below who they are, when they have Anxiety and more.

On Apr, 11, 2014: 2,159 people reported to have side effects when taking Melatonin. Among them, 145 people (6.72%) have Anxiety. They amount to 0.01% of all the 1,276,157 people who have Anxiety on eHealthMe.

Trend of Anxiety in Melatonin reports

Time on Melatonin when people have Anxiety * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Anxiety12.50%37.50%12.50%0.00%25.00%0.00%12.50%

Gender of people who have Anxiety when taking Melatonin * :

FemaleMale
Anxiety64.75%35.25%

Age of people who have Anxiety when taking Melatonin * :

0-12-910-1920-2930-3940-4950-5960+
Anxiety0.00%0.75%3.73%2.99%3.73%24.63%26.87%37.31%

Severity of Anxiety when taking Melatonin ** :

leastmoderateseveremost severe
Anxiety0.00%62.50%12.50%25.00%

How people recovered from Anxiety ** :

while on the drugafter off the drugnot yet
Anxiety0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Pain (34 people, 23.45%)
  2. Anxiety (33 people, 22.76%)
  3. Depression (26 people, 17.93%)
  4. Sleep disorder (16 people, 11.03%)
  5. Prophylaxis (14 people, 9.66%)

Top co-used drugs for these people * :

  1. Zometa (72 people, 49.66%)
  2. Tamoxifen citrate (43 people, 29.66%)
  3. Zithromax (37 people, 25.52%)
  4. Celebrex (36 people, 24.83%)
  5. Ambien (35 people, 24.14%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Melatonin, Anxiety

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On eHealthMe, Melatonin (melatonin) is often used for insomnia. Find out below the conditions Melatonin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Melatonin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (6 months ago):

  • Anxiety especially noticeable while attempting to sleep.

    Reply

  • From this study (6 months ago):

  • Left side facial nerve pain due to enlarged cheekbone pressing on 5 th cranial nerve. Believed to have also trigeminal neuralgia type 2 due to procedures in attempts to alleviate cranial nerve pain.
    Diagnosed with pseudoporphyria 2 months ago. Believed to be brought on by nsaid medications. Auto immune diseases not tested for or ruled out.
    Severe anxiety correlates with timing of first symptoms of porphyria

    Reply

  • From this study (2 years ago):

  • Severe anxiety. Mother is lying about him being on the sleep aid.

    Reply

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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