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Review: could Melatonin cause Headaches?

Summary: Headaches could be caused by Melatonin, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take Ambien, and have Prophylaxis.

We study 2,128 people who have side effects while taking Melatonin from FDA and social media. Among them, 145 have Headaches. Find out below who they are, when they have Headaches and more.

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Melatonin

Melatonin (latest outcomes from 2,573 users) has active ingredients of melatonin. It is often used in insomnia.

Headaches

Headaches (pain in head) (latest reports from 1,202,963 patients) has been reported by people with multiple sclerosis, high blood pressure, depression, rheumatoid arthritis, osteoporosis.

On Apr, 10, 2014: 2,159 people reported to have side effects when taking Melatonin. Among them, 144 people (6.67%) have Headaches. They amount to 0.01% of all the 1,201,309 people who have Headaches on eHealthMe.

Trend of Headaches in Melatonin reports

Time on Melatonin when people have Headaches * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Headaches21.43%21.43%14.29%14.29%28.57%0.00%0.00%

Gender of people who have Headaches when taking Melatonin * :

FemaleMale
Headaches70.21%29.79%

Age of people who have Headaches when taking Melatonin * :

0-12-910-1920-2930-3940-4950-5960+
Headaches0.00%4.20%13.45%13.45%10.92%16.81%15.97%25.21%

Severity of Headaches when taking Melatonin ** :

leastmoderateseveremost severe
Headaches16.67%58.33%25.00%0.00%

How people recovered from Headaches ** :

while on the drugafter off the drugnot yet
Headaches12.50%25.00%62.50%

Top conditions involved for these people * :

  1. Prophylaxis (23 people, 15.97%)
  2. Pain (17 people, 11.81%)
  3. Insomnia (16 people, 11.11%)
  4. Depression (14 people, 9.72%)
  5. Gynaecomastia (12 people, 8.33%)

Top co-used drugs for these people * :

  1. Ambien (42 people, 29.17%)
  2. Zometa (31 people, 21.53%)
  3. Lorazepam (22 people, 15.28%)
  4. Aredia (22 people, 15.28%)
  5. Celebrex (22 people, 15.28%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Melatonin, Headaches

You can also:

On eHealthMe, Melatonin (melatonin) is often used for insomnia. Find out below the conditions Melatonin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Melatonin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

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  • I have Pityriasis and poor bood circulation.

    Reply

  • From this study (12 months ago):

  • The pill for insomnia called ambien I only take rarely, as is valium. Only when having anxiety attacks. One pill has all the herbs and supplements. It is calledPower to Sleep

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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