Melatonin and Serotonin syndrome - from FDA reports


Summary

Serotonin syndrome is found among people who take Melatonin, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Cymbalta, and have Depression. This review analyzes which people have Serotonin syndrome with Melatonin. It is created by eHealthMe based on reports of 8,226 people who have side effects when taking Melatonin from FDA, and is updated regularly.

What to expect?

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On Mar, 23, 2017

8,226 people reported to have side effects when taking Melatonin.
Among them, 26 people (0.32%) have Serotonin Syndrome


Number of reports submitted per year:

Could Melatonin cause Serotonin syndrome?

Time on Melatonin when people have Serotonin Syndrome *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Serotonin Syndrome when taking Melatonin *:

  • female: 83.33 %
  • male: 16.67 %

Age of people who have Serotonin Syndrome when taking Melatonin *:

  • 0-1: 0.0 %
  • 2-9: 17.39 %
  • 10-19: 21.74 %
  • 20-29: 4.35 %
  • 30-39: 13.04 %
  • 40-49: 8.7 %
  • 50-59: 8.7 %
  • 60+: 26.09 %

Top conditions involved for these people *:

  • Stress And Anxiety (8 people, 30.77%)
  • Depression (8 people, 30.77%)
  • Rashes (5 people, 19.23%)
  • Pain (5 people, 19.23%)
  • Diarrhea (5 people, 19.23%)

Top co-used drugs for these people *:

  • Cymbalta (6 people, 23.08%)
  • Zoloft (5 people, 19.23%)
  • Promethazine (5 people, 19.23%)
  • Ondansetron (5 people, 19.23%)
  • Fluoxetine (5 people, 19.23%)

Top other side effects for these people *:

  • Hyperhidrosis (6 people, 23.08%)
  • Mydriasis (5 people, 19.23%)
  • Agitation (5 people, 19.23%)
  • Headache (4 people, 15.38%)
  • Dizziness (4 people, 15.38%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Serotonin syndrome when taking Melatonin?

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 9,347 users)

Serotonin Syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, insomnia (latest reports from 9,744 Serotonin syndrome patients).

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