Review: could Melatonin cause Serotonin syndrome?
(By eHealthMe on Mar, 6, 2014)
Severity ratings: 2.0/4
On a scale of 1 to 4: 1=least, 2=moderate, 3=severe, 4=most severe
We study 2,144 people who take Melatonin. Among them, 6 have Serotonin syndrome. See who they are, when they have Serotonin syndrome and more. This review is based on reports from FDA and social media, and is updated regularly.
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Melatonin (latest outcomes from 2,545 users) has active ingredients of melatonin. It is often used in insomnia, sleep disorder. Commonly reported side effects of Melatonin include fatigue, pain, pain exacerbated, fatigue aggravated, nausea aggravated.
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) (latest reports from 33,371 patients) has been reported by people with depression, pain, stress and anxiety, major depression, bipolar disorder.
On Mar, 6, 2014: 2,144 people reported to have side effects when taking Melatonin. Among them, 6 people (0.28%) have Serotonin Syndrome.
Time on Melatonin when people have Serotonin syndrome * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Serotonin syndrome||0.00||0.00||0.00||0.00||0.00||0.00||0.00 |
Gender of people who have Serotonin syndrome when taking Melatonin * :
|Serotonin syndrome||83.33%||16.67% |
Age of people who have Serotonin syndrome when taking Melatonin * :
|Serotonin syndrome||0.00%||0.00%||0.00%||16.67%||0.00%||33.33%||0.00%||50.00% |
Severity of Serotonin syndrome when taking Melatonin ** :
|least||moderate||severe||most severe |
|Serotonin syndrome||0.00%||100.00%||0.00%||0.00% |
How people recovered from Serotonin syndrome ** :
|while on the drug||after off the drug||not yet |
|Serotonin syndrome||0.00%||0.00%||100.00% |
Top conditions involved for these people * :
- Depression (4 people, 66.67%)
- Pain (2 people, 33.33%)
- Pneumonia (2 people, 33.33%)
- Hypertension (2 people, 33.33%)
- Pyrexia (2 people, 33.33%)
Top co-used drugs for these people * :
- Zyvox (3 people, 50.00%)
- Lopressor (3 people, 50.00%)
- Zoloft (3 people, 50.00%)
- Lisinopril (2 people, 33.33%)
- Mirapex (2 people, 33.33%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
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Related topic: Melatonin, Serotonin syndrome
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From this study (1 year ago):
Had it since Saturday. Having Anxiety attacks, then randomly in a good mood, my brain feels like it's going on overdrive, constantly feeling like I've been here before. Face muscles contract and relax spuriously, and have thoughts of death.
Julie on Oct, 14, 2012:
I ALSO have that happen to me, every single time I take a Tizanidine. I start thinking about death and become very afraid. It's a scary feeling; indescribable.
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