Review: could Mercaptopurine cause Hypoglycaemia?


Summary

Hypoglycaemia is found among people who take Mercaptopurine, especially for people who are male, 2-9 old , have been taking the drug for 1 - 2 years, also take medication Methotrexate, and have Acute lymphocytic leukaemia . We study 6,286 people who have side effects while taking Mercaptopurine from FDA and social media. Among them, 23 have Hypoglycaemia. Find out below who they are, when they have Hypoglycaemia and more.

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Mercaptopurine

Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. (latest outcomes from Mercaptopurine 6,762 users)

Hypoglycaemia

Hypoglycaemia (deficiency of glucose in the bloodstream) has been reported by people with breathing difficulty, hypotension, ards (acute respiratory distress syndrome), drowsiness, diarrhea (latest reports from 23,539 Hypoglycaemia patients).

On Aug, 30, 2016

6,286 people reported to have side effects when taking Mercaptopurine.
Among them, 23 people (0.37%) have Hypoglycaemia


Number of reports submitted per year:

Could Mercaptopurine cause Hypoglycaemia?

Time on Mercaptopurine when people have Hypoglycaemia *:

  • < 1 month: 25 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Hypoglycaemia when taking Mercaptopurine *:

  • female: 43.48 %
  • male: 56.52 %

Age of people who have Hypoglycaemia when taking Mercaptopurine *:

  • 0-1: 0.0 %
  • 2-9: 57.14 %
  • 10-19: 28.57 %
  • 20-29: 4.76 %
  • 30-39: 0.0 %
  • 40-49: 4.76 %
  • 50-59: 0.0 %
  • 60+: 4.76 %

Severity if Hypoglycaemia when taking Mercaptopurine **:

  • least: 0.0 %
  • moderate: 66.67 %
  • severe: 33.33 %
  • most severe: 0.0 %

How people recovered from Hypoglycaemia **:

  • while on drug: 50 %
  • after off the drug: 50 %
  • not yet: 0.0 %

Top conditions involved for these people *:

  • Acute Lymphocytic Leukaemia (9 people, 39.13%)
  • Crohn's Disease (2 people, 8.70%)
  • Acute Lymphoblastic Leukemia (2 people, 8.70%)
  • Rectal Lesion (1 person, 4.35%)
  • Pyoderma Gangrenosum (1 person, 4.35%)

Top co-used drugs for these people *:

  • Methotrexate (16 people, 69.57%)
  • Vincristine (7 people, 30.43%)
  • Prednisone (7 people, 30.43%)
  • Dexamethasone (5 people, 21.74%)
  • Vincristine Sulfate (4 people, 17.39%)

Top other side effects for these people *:

  • Sepsis (3 people, 13.04%)
  • Nausea (3 people, 13.04%)
  • Hypotension (3 people, 13.04%)
  • Dehydration (3 people, 13.04%)
  • Asthenia (3 people, 13.04%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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